Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Dongrong Yi"'
Autor:
Dongrong Yi, Ni An, Quanjie Li, Qian Liu, Huihan Shao, Rui Zhou, Jing Wang, Yongxin Zhang, Ling Ma, Fei Guo, Xiaoyu Li, Zhenlong Liu, Shan Cen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 6, Pp 2520-2536 (2024)
Type I interferon (IFN) inhibits a wide spectrum of viruses through stimulating the expression of antiviral proteins. As an IFN-induced protein, myxovirus resistance B (MXB) protein was reported to inhibit multiple highly pathogenic human viruses. It
Externí odkaz:
https://doaj.org/article/83310836f69e477fba2ba64d410f6ae6
Autor:
Jiwei Ding, Shujie Wang, Qipeng Liu, Yuqing Duan, Tingting Cheng, Zhongjie Ye, Zhanding Cui, Ao Zhang, Qiuyu Liu, Zixiong Zhang, Ning Zhang, Qian Liu, Ni An, Jianyuan Zhao, Dongrong Yi, Quanjie Li, Jing Wang, Yongxin Zhang, Ling Ma, Saisai Guo, Jinhui Wang, Chen Liang, Jinming Zhou, Shan Cen, Xiaoyu Li
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107968- (2023)
Summary: Long interspersed element 1 (LINE-1) is the only currently known active autonomous transposon in humans, and its retrotransposition may cause deleterious effects on the structure and function of host cell genomes and result in sporadic genet
Externí odkaz:
https://doaj.org/article/a874c567f5d344b7b3f7258a95bf08e8
Autor:
Saisai Guo, Xiaobo Lei, Yan Chang, Jianyuan Zhao, Jing Wang, Xiaojing Dong, Qian Liu, Zixiong Zhang, Lidan Wang, Dongrong Yi, Ling Ma, Quanjie Li, Yongxin Zhang, Jiwei Ding, Chen Liang, Xiaoyu Li, Fei Guo, Jianwei Wang, Shan Cen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract The coronavirus disease 2019 (COVID-19) pandemic has devastated global health. Identifying key host factors essential for SARS-CoV-2 RNA replication is expected to unravel cellular targets for the development of broad-spectrum antiviral drug
Externí odkaz:
https://doaj.org/article/ffbcda39b3154046b3276edad622a296
Autor:
Dongrong Yi, Quanjie Li, Han Wang, Kai Lv, Ling Ma, Yujia Wang, Jing Wang, Yongxin Zhang, Mingliang Liu, Xiaoyu Li, Jianxun Qi, Yi Shi, George F. Gao, Shan Cen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 12, Pp 4378-4389 (2022)
Ebola virus (EBOV) infection leads to staggeringly high mortality rate. Effective and low-cost treatments are urgently needed to control frequent EBOV outbreaks in Africa. In this study, we report that a natural compound called berbamine hydrochlorid
Externí odkaz:
https://doaj.org/article/6584f2d9c9894167abc340200ae813b4
Autor:
Jianyuan Zhao, Jing Wang, Xu Pang, Zhenlong Liu, Quanjie Li, Dongrong Yi, Yongxin Zhang, Xiaomei Fang, Tao Zhang, Rui Zhou, Zhe Guo, Wancang Liu, Xiaoyu Li, Chen Liang, Tao Deng, Fei Guo, Liyan Yu, Shan Cen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Abstract The emergence of new highly pathogenic and drug-resistant influenza strains urges the development of novel therapeutics for influenza A virus (IAV). Here, we report the discovery of an anti-IAV microbial metabolite called APL-16-5 that was o
Externí odkaz:
https://doaj.org/article/484ba5477ebd45ccab2bc587cc1ab036
Autor:
Jianyuan Zhao, Jing Wang, Xu Pang, Zhenlong Liu, Quanjie Li, Dongrong Yi, Yongxin Zhang, Xiaomei Fang, Tao Zhang, Rui Zhou, Zhe Guo, Wancang Liu, Xiaoyu Li, Chen Liang, Tao Deng, Fei Guo, Liyan Yu, Shan Cen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/7a5bb60f3e18467489a2b3ee36ac44eb
Autor:
Ni An, Qinghua Ge, Huihan Shao, Quanjie Li, Fei Guo, Chen Liang, Xiaoyu Li, Dongrong Yi, Long Yang, Shan Cen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundType I interferon (IFN) inhibits virus infection through multiple processes. Recent evidence indicates that IFN carries out its antiviral activity through readjusting of the cellular metabolism. The sterile alpha motif and histidine-asparta
Externí odkaz:
https://doaj.org/article/7c2a73cd4a1e4e08a495d645b56a3765
Autor:
Zixiong Zhang, Ning Zhang, Saisai Guo, Qian Liu, Shujie Wang, Ao Zhang, Dongrong Yi, Jianyuan Zhao, Quanjie Li, Jing Wang, Yongxin Zhang, Ling Ma, Jiwei Ding, Shan Cen, Xiaoyu Li
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Long-interspersed element 1 (LINE-1) is an autonomous non-LTR retrotransposon. Its replication can cause mutation and rearrangement of host genomic DNA, which may result in serious genetic diseases. Host cells therefore developed defense strategies t
Externí odkaz:
https://doaj.org/article/483c79c1cfe9430ba22dcb9d992d3c53
Autor:
Quanjie Li, Dongrong Yi, Xiaobo Lei, Jianyuan Zhao, Yongxin Zhang, Xiangling Cui, Xia Xiao, Tao Jiao, Xiaojing Dong, Xuesen Zhao, Hui Zeng, Chen Liang, Lili Ren, Fei Guo, Xiaoyu Li, Jianwei Wang, Shan Cen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1555-1567 (2021)
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become one major threat to human population health. The RNA-dependent RNA polymerase (RdRp) presents an ideal target of antivirals, whereas nucleoside analogs inhibitor is hindered by t
Externí odkaz:
https://doaj.org/article/89b3e8c0b280419b976515324f07ba97
Autor:
Yanni Kou, Shujie Wang, Yanjie Ma, Ning Zhang, Zixiong Zhang, Qian Liu, Yang Mao, Rui Zhou, Dongrong Yi, Ling Ma, Yongxin Zhang, Quanjie Li, Jing Wang, Jinhui Wang, Xile Zhou, Chunnian He, Jiwei Ding, Shan Cen, Xiaoyu Li
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Long interspersed nuclear element 1 (LINE-1) is a dominant autonomous retrotransposon in human genomes which plays a role in affecting the structure and function of somatic genomes, resulting in human disorders including genetic disease and cancer. L
Externí odkaz:
https://doaj.org/article/f921cc61a54747e2bc63936a128672c7