Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Dongrong Chen"'
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background The aminoglycosides are established antibiotics that inhibit bacterial protein synthesis by binding to ribosomal RNA. Additional non-antibiotic aminoglycoside cellular functions have also been identified through aminoglycoside int
Externí odkaz:
https://doaj.org/article/46b8b277c7054196b174da37f43454f5
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Aminoglycosides are not only antibiotics but also have wider and diverse non-antibiotic cellular functions. To elucidate the understanding of non-antibiotic cellular functions, here we report transcriptome-profiling analysis of Escherichia coli in th
Externí odkaz:
https://doaj.org/article/53ee050a32b34c26ba04571368dc4413
Autor:
Jun Zhang, Getong Liu, Xuhui Zhang, Yaowen Chang, Shasha Wang, Weizhi He, Wenxia Sun, Dongrong Chen, Alastair I.H. Murchie
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 1432-1442 (2020)
The proliferation of antibiotic resistance has its origins in horizontal gene transfer. The class 1 integrons mediate gene transfer by assimilating antibiotic-resistance genes through site-specific recombination. For the class 1 integrons the first a
Externí odkaz:
https://doaj.org/article/ff16ce90bb8a4f588f08c269fbee32b0
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122972 (2015)
The proliferation of antibiotic resistant pathogens is an increasing threat to the general public. Resistance may be conferred by a number of mechanisms including covalent or mutational modification of the antibiotic binding site, covalent modificati
Externí odkaz:
https://doaj.org/article/fed8c96bc23048f3a547c19d4e309631
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28275 (2011)
BACKGROUND: Hydrogen sulfide (H(2)S) is a newly identified member of the small family of gasotransmitters that are endogenous gaseous signaling molecules that have a fundamental role in human biology and disease. Although it is a relatively recent di
Externí odkaz:
https://doaj.org/article/797865b10b41495ca06cd60c27559ff6
Autor:
Xingchen Huang, Qinqiang Sun, Dongrong Chen, Weihan Yang, Junjun Zhang, Runfeng Liu, Pengfei Zhang, Liangfeng Huang, Ming Zhang, Qiang Fu
Publikováno v:
Reproduction in Domestic Animals. 57:481-488
Maternal-effect genes (MEGs) accumulate in oocytes during oogenesis and mediate the pre-implantation embryo developmental programme until activation of the zygote genome. Nlrp5 and Tle6 are required for normal pre-implantation and embryonic developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9ce4166496acb655f6305d66025611
https://doi.org/10.1111/rda.14084
https://doi.org/10.1111/rda.14084
Publikováno v:
Nature Catalysis. 4:872-881
RNA methylations contribute to a wide range of cellular functions. Cellular RNAs are usually methylated by protein methyltransferases using S-adenosyl-l-methionine (SAM) as a cofactor. Here we report the in vitro selection of a 33-nucleotide SAM-depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f51f10ba3d7c8feb4af12a1a5a5071ca
https://doi.org/10.1038/s41929-021-00685-z
https://doi.org/10.1038/s41929-021-00685-z
Publikováno v:
The FEBS Journal. 288:1586-1598
Interactions between aminoglycoside antibiotics and the twister ribozyme were investigated in this study. An initial screen of 17 RNA-binding antibiotics showed that a number of aminoglycosides inhibit the ribozyme, while a subset of aminoglycosides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b4c60439c36c0d179005ab0d55d518
https://doi.org/10.1111/febs.15517
https://doi.org/10.1111/febs.15517
Publikováno v:
RNA. 26:137-149
The 5′ untranslated regions (5′ UTR) of mRNAs play an important role in the eukaryotic translation initiation process. Additional levels of translational regulation may be mediated through interactions between structured mRNAs that can adopt inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4004515511df4bb4a33bb8e323c6af5
https://doi.org/10.1261/rna.072975.119
https://doi.org/10.1261/rna.072975.119
Background: Aminoglycosides are not only antibiotics but also have wider and diverse non-antibiotic cellular functions. No genome-wide study focusing on the changes of gene expression by aminoglycosides in E.coli has been reported. Here, we report tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d0e33f07b5865602b487af1236171e6
https://doi.org/10.21203/rs.3.rs-1066022/v1
https://doi.org/10.21203/rs.3.rs-1066022/v1
