Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Dongqing Huang"'
Autor:
Jeffrey R. Whiteaker, Lei Zhao, Regine M. Schoenherr, Dongqing Huang, Jacob J. Kennedy, Richard G. Ivey, Chenwei Lin, Travis D. Lorentzen, Simona Colantonio, Tessa W. Caceres, Rhonda R. Roberts, Joseph G. Knotts, Joshua J. Reading, Candice D. Perry, Sandra S. Garcia-Buntley, William Bocik, Stephen M. Hewitt, Amanda G. Paulovich
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-13 (2024)
Abstract Immunotherapies are revolutionizing cancer care, but many patients do not achieve durable responses and immune-related adverse events are difficult to predict. Quantifying the hundreds of proteins involved in cancer immunity has the potentia
Externí odkaz:
https://doaj.org/article/2899dcf47f47466f938dcdf8b51eceb7
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/f9efb04fafce45cfb9bc82a4d4c35b3a
Autor:
Jeffrey R. Whiteaker, Lei Zhao, Regine M. Schoenherr, Dongqing Huang, Rachel A. Lundeen, Ulianna Voytovich, Jacob J. Kennedy, Richard G. Ivey, Chenwei Lin, Oscar D. Murillo, Travis D. Lorentzen, Simona Colantonio, Tessa W. Caceres, Rhonda R. Roberts, Joseph G. Knotts, Joshua J. Reading, Candice D. Perry, Christopher W. Richardson, Sandra S. Garcia-Buntley, William Bocik, Stephen M. Hewitt, Shrabanti Chowdhury, Jackie Vandermeer, Stephen D. Smith, Ajay K. Gopal, Nirasha Ramchurren, Steven P. Fling, Pei Wang, Amanda G. Paulovich
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionImmunotherapy is an effective treatment for a subset of cancer patients, and expanding the benefits of immunotherapy to all cancer patients will require predictive biomarkers of response and immune-related adverse events (irAEs). To suppo
Externí odkaz:
https://doaj.org/article/f412d3d737e448d4a0f5abc24df6f60b
Autor:
Yuxin Zheng, Shijuan Lang, Junjie Liang, Yongchun Jiang, Biyi Zhao, Hongxin Chen, Dongqing Huang, Qinyi Li, Huijin Liu, Shudi Chen, Anniwaer Yilifate, Fangqiu Xu, Haining Ou, Qiang Lin
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
BackgroundMild cognitive impairment (MCI) is considered a transitional stage between cognitive normality and dementia among the elderly, and its associated risk of developing Alzheimer’s disease (AD) is 10–15 times higher than that of the general
Externí odkaz:
https://doaj.org/article/e292886b781f4dbe8f04d9cb8a357bd0
Publikováno v:
International Journal of Infectious Diseases, Vol 106, Iss , Pp 386-394 (2021)
Objectives: From 2013 to 2017, the avian influenza A (H7N9) virus frequently infected people in China, which seriously affected the public health of society. This study aimed to analyze the spatial characteristics of human infection with the H7N9 vir
Externí odkaz:
https://doaj.org/article/157e1648aae34ca3b6c3a4468844e675
Publikováno v:
International Journal of Infectious Diseases, Vol 105, Iss , Pp 675-685 (2021)
Objectives: The purpose of this study was to explore the temporal and spatial characteristics of COVID-19 transmission and its influencing factors in China, from January to October 2020. Methods: About 81,000 COVID-19 confirmed case data, Baidu migra
Externí odkaz:
https://doaj.org/article/d35a132f9c8b4687a38d85f4d5cd828d
Autor:
Jing Yuan, Hua Lan, Dongqing Huang, Xiaohui Guo, Chu Liu, Shuping Liu, Peng Zhang, Yan Cheng, Songshu Xiao
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Minichromosome maintenance 2 (MCM2) is a member of the minichromosomal maintenance family of proteins that mainly regulates DNA replication and the cell cycle and is involved in regulating cancer cell proliferation in various cancers. Previous studie
Externí odkaz:
https://doaj.org/article/2f77ffdc83d14b3b976e4d9283b62110
Autor:
Jeffrey R. Whiteaker, Rachel A. Lundeen, Lei Zhao, Regine M. Schoenherr, Aura Burian, Dongqing Huang, Ulianna Voytovich, Tao Wang, Jacob J. Kennedy, Richard G. Ivey, Chenwei Lin, Oscar D. Murillo, Travis D. Lorentzen, Mathangi Thiagarajan, Simona Colantonio, Tessa W. Caceres, Rhonda R. Roberts, Joseph G. Knotts, Joshua J. Reading, Jan A. Kaczmarczyk, Christopher W. Richardson, Sandra S. Garcia-Buntley, William Bocik, Stephen M. Hewitt, Karen E. Murray, Nhan Do, Mary Brophy, Stephen W. Wilz, Hongbo Yu, Samuel Ajjarapu, Emily Boja, Tara Hiltke, Henry Rodriguez, Amanda G. Paulovich
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Immunotherapies are revolutionizing cancer care, producing durable responses and potentially cures in a subset of patients. However, response rates are low for most tumors, grade 3/4 toxicities are not uncommon, and our current understanding of tumor
Externí odkaz:
https://doaj.org/article/2231b7f4bf4c4dfdac9a7d21bf8f78b2
Autor:
Jeffrey R. Whiteaker, Tao Wang, Lei Zhao, Regine M. Schoenherr, Jacob J. Kennedy, Ulianna Voytovich, Richard G. Ivey, Dongqing Huang, Chenwei Lin, Simona Colantonio, Tessa W. Caceres, Rhonda R. Roberts, Joseph G. Knotts, Jan A. Kaczmarczyk, Josip Blonder, Joshua J. Reading, Christopher W. Richardson, Stephen M. Hewitt, Sandra S. Garcia-Buntley, William Bocik, Tara Hiltke, Henry Rodriguez, Elizabeth A. Harrington, J. Carl Barrett, Benedetta Lombardi, Paola Marco-Casanova, Andrew J. Pierce, Amanda G. Paulovich
Publikováno v:
Cancers, Vol 13, Iss 15, p 3843 (2021)
The ATM serine/threonine kinase (HGNC: ATM) is involved in initiation of repair of DNA double-stranded breaks, and ATM inhibitors are currently being tested as anti-cancer agents in clinical trials, where pharmacodynamic (PD) assays are crucial to he
Externí odkaz:
https://doaj.org/article/3167630f139d43ff8d13d8fc3f1237df
Autor:
Dongqing Huang, Supipi Kaluarachchi, Dewald van Dyk, Helena Friesen, Richelle Sopko, Wei Ye, Nazareth Bastajian, Jason Moffat, Holly Sassi, Michael Costanzo, Brenda J Andrews
Publikováno v:
PLoS Biology, Vol 7, Iss 9, p e1000188 (2009)
START-dependent transcription in Saccharomyces cerevisiae is regulated by two transcription factors SBF and MBF, whose activity is controlled by the binding of the repressor Whi5. Phosphorylation and removal of Whi5 by the cyclin-dependent kinase (CD
Externí odkaz:
https://doaj.org/article/c012ef67db6845d185e3cb64673b38bf