Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Dongqin Yu"'
Autor:
Zhenqi Liu, Dongqin Yu, Hualong Song, Miles L. Postings, Peter Scott, Zhao Wang, Jinsong Ren, Xiaogang Qu
Publikováno v:
ACS Nano. 17:8141-8152
Publikováno v:
Chemical Communications. 57:2641-2644
An amphiphilic taurocholic acid (TCA) doped polypyrrole (PPy) film (PPy/TCA) was used as a dynamic mimic membrane model to explore how switchable surface wettability influences amyloid aggregation. Our results indicate that the hydrophobic surface, n
Publikováno v:
Angewandte Chemie International Edition. 61
Post-translational modification (PTM) of protein can significantly change protein conformation and function. Inspired by the natural PTM, we present a new approach to inhibit amyloid aggregation by chemical PTM modification. Polyoxometalates (POMs) w
Publikováno v:
Angewandte Chemie (International ed. in English). 61(28)
Herein we present a new way to encapsulate neural stem cells (NSCs) by using hydrogen-bonded organic frameworks (HOFs) to overcome the common causes of low therapeutic efficacy during NSC transplantation: 1) loss of fundamental stem cell properties,
Publikováno v:
Chemical Science
Photo-oxygenation of β-amyloid (Aβ) has been considered an efficient way to inhibit Aβ aggregation in Alzheimer's disease (AD). However, current photosensitizers cannot simultaneously achieve enhanced blood–brain barrier (BBB) permeability and s
Publikováno v:
ACS Nano. 13:9206-9217
Nanoscale porphyrinic metal-organic frameworks (NMOFs) have emerged as promising therapeutic platforms for the photodynamic therapy (PDT) of cancer in recent years. However, the relatively large sizes of current NMOFs ranging from tens to hundreds of
Publikováno v:
Angewandte Chemie (International ed. in English). 61(2)
Phototherapy has emerged as a powerful approach for interrupting β-amyloid (Aβ) self-assembly. However, deeper tissue penetration and safer photosensitizers are urgent to be exploited for avoiding damaging nearby normal tissues and improving therap
Publikováno v:
Chemical Science
Oligomeric and fibrillar amyloid-β (Aβ) are principally internalized via receptor-mediated endocytosis (RME) by microglia, the main scavenger of Aβ in the brain. Nevertheless, the inflammatory cascade will be evoked after vast Aβ aggregate bindin
Publikováno v:
Chemical Science
Acute kidney injury (AKI) is a syndrome characterized by rapid loss of renal excretory function with high in-hospital mortality. The excess generation of reactive oxygen species (ROS) in the kidneys during AKI has been considered a major cause of ren
Publikováno v:
Chemical Communications. 55:9833-9836
Herein, through using electropolymerized pyrrole (PPy) to coat near-infrared upconversion nanoparticles (UCNPs) on an indium tin oxide (ITO) electrode, the as-prepared PPy/UCNPs photoelectrode could generate an interfacial electric field, release rar