Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Dongna Zhang"'
Autor:
Mei Li, Zhu-Chun Bei, Yongtian Yuan, Baogang Wang, Dongna Zhang, Likun Xu, Liangliang Zhao, Qin Xu, Yabin Song
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
Papain-like protease (PLpro) is an attractive anti-coronavirus target. The development of PLpro inhibitors, however, is hampered by the limitations of the existing PLpro assay and the scarcity of validated active compounds. We developed a novel in-ce
Externí odkaz:
https://doaj.org/article/5a01b9e861734741bbb82b9fba6c65f7
Autor:
Ruotong Liu, Guoming Li, Mei Li, Baogang Wang, Dongna Zhang, Likun Xu, Liangliang Zhao, Ruhe Liao, Qin Xu, Zhu-Chun Bei, Yabin Song
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 7 (2024)
ABSTRACT Naphthoquine is a promising candidate for antimalarial combination therapy. Its combination with artemisinin has demonstrated excellent efficacy in clinical trials conducted across various malaria-endemic areas. A co-formulated combination o
Externí odkaz:
https://doaj.org/article/96a54aa90e314be9a031f5d890a34312
Autor:
Zhu-Chun Bei, Huanhuan Yu, Hong Wang, Qingyun Li, Baogang Wang, Dongna Zhang, Likun Xu, Liangliang Zhao, Shuwei Dong, Yabin Song
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTThe main protease (3-chymotrypsin-like protease, 3CLpro) of SARS-CoV-2 has become a focus of anti-coronavirus research. Despite efforts, drug development targeting 3CLpro has been hampered by limitations in the currently available activity as
Externí odkaz:
https://doaj.org/article/25113ab9400d4eaa9989cb77deafb417
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
Vaccines are essential to create a more resilient economic growth model. Ending the COVID-19 pandemic requires a more coordinated, effective, and equitable distribution of vaccines across the countries. Therefore, governments are in a race to increas
Externí odkaz:
https://doaj.org/article/cb2a25b30c2c43f79bb91438a6c18ad0
Publikováno v:
Molecules, Vol 28, Iss 4, p 1579 (2023)
The Lassa virus (LASV) causes Lassa fever, a highly infectious and lethal agent of acute viral hemorrhagic fever. At present, there are still no effective treatments available, creating an urgent need to develop novel therapeutics. Some benzimidazole
Externí odkaz:
https://doaj.org/article/7dfb92f697054a98aa29414fb822dc45
Autor:
Menghuan Zhu, Dongna Zhang, Lili Zhang, Liangliang Zhao, Likun Xu, Baogang Wang, Xinyu Zhang, Jinwei Chen, Zhuchun Bei, Hong Wang, Dongsheng Zhou, Wenhui Yang, Yabin Song
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2646 (2022)
Infection with Yersinia pestis (Y. pestis) may cause pneumonic plague, which is inevitably fatal without treatment. Gentamicin (GM), an aminoglycoside antibiotic, is a drug commonly used in the treatment of plague. However, it requires repeated intra
Externí odkaz:
https://doaj.org/article/d903cb8599754be49e6513f1e03c7de4
Publikováno v:
Results in Chemistry, Vol 3, Iss , Pp 100191- (2021)
We report a one-step method for the synthesis of alkoxy substituted pyrazine derivatives. The process makes use of an improved acid-mediated coupling reaction to afford the products in good yields (70–90%). This method expands the scope to alkoxy s
Externí odkaz:
https://doaj.org/article/30f91e79c0c54ed48287b96cdd07810e
Autor:
Yabin Song, Yongqiang Deng, Huiqiang Wang, Zhuchun Bei, Hongjing Gu, Hui Zhao, Hong Wang, Dongna Zhang, Likun Xu, Baogang Wang, Yuhuan Li, Hongquan Wang
Publikováno v:
Molecules, Vol 27, Iss 3, p 712 (2022)
COVID-19 has spread around the world and caused serious public health and social problems. Although several vaccines have been authorized for emergency use, new effective antiviral drugs are still needed. Some repurposed drugs including Chloroquine,
Externí odkaz:
https://doaj.org/article/517110766a4c44adbe05db97c77ddb95
Publikováno v:
Atmosphere, Vol 11, Iss 1, p 93 (2020)
The trend of tropical-cyclone (TC) translation speed is a hot topic recently. Changes in TC translation speed during 1949−2017 over the western North Pacific are analyzed using two best-track datasets here. The TC translation speed decreased during
Externí odkaz:
https://doaj.org/article/31eda596d2194effbc79dafcdd223ef2
Publikováno v:
Journal of Testing & Evaluation; Jul2024, Vol. 52 Issue 4, p1-12, 12p