Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Dongmei Cun"'
Autor:
Haoyu Lu, Xulu Liu, Mengjun Zhang, Hriday Bera, Wenwen Xu, Huiyang Jiang, Xing Zhao, Lan Wu, Dongmei Cun, Mingshi Yang
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 19, Iss 4, Pp 100929- (2024)
Idiopathic pulmonary fibrosis (IPF) is a progressive pulmonary disease that leads to interstitial inflammation, lung damage, and eventually life-threatening complications. Among various pathologic factors, Smad4 is a pivotal molecule involved in the
Externí odkaz:
https://doaj.org/article/322b2553a7044654b032a098c27231b1
Publikováno v:
Acta Materia Medica, Vol 2, Iss 2, Pp 142-156 (2023)
The current study focused on the formulation, physicochemical characterization, and antibacterial susceptibility testing of inhalable spray dried powders containing ciprofloxacin (CIP) and polymyxin B sulfate (PMB). CIP nanosuspensions with an averag
Externí odkaz:
https://doaj.org/article/2a80f44489d944d680721d9f8b68baed
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 429 (2024)
Alveolar macrophages play a vital role in a variety of lung diseases, including tuberculosis. Thus, alveolar macrophage targeted anti-tubercular drug delivery through nanocarriers could improve its therapeutic response against tuberculosis. The curre
Externí odkaz:
https://doaj.org/article/c4cc6a4dd93040f3b2f0d5671b1d0152
Autor:
Liangwei Si, Xiong Guo, Hriday Bera, Yang Chen, Fangfang Xiu, Peixin Liu, Chunwei Zhao, Yasir Faraz Abbasi, Xing Tang, Vito Foderà, Dongmei Cun, Mingshi Yang
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 18, Iss 6, Pp 100856- (2023)
Burn injury is a serious public health problem and scientists are continuously aiming to develop promising biomimetic dressings for effective burn wound management. In this study, a greater efficacy in burn wound healing and the associated mechanisms
Externí odkaz:
https://doaj.org/article/414fe62f4d744bab9afd06fdd70f23c5
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2287 (2023)
Respiratory antibiotics delivery has been appreciated for its high local concentration at the infection sites. Certain formulation strategies are required to improve pulmonary drug exposure and to achieve effective antimicrobial activity, especially
Externí odkaz:
https://doaj.org/article/6042943fe3f44a09ac4b1c99ed9c8255
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2565-2584 (2021)
Pulmonary administration route has been extensively exploited for the treatment of local lung diseases such as asthma, chronic obstructive pulmonary diseases and respiratory infections, and systemic diseases such as diabetes. Most inhaled medicines c
Externí odkaz:
https://doaj.org/article/be9d375a852741dca8285c732a25a77b
Autor:
Changzhi Shi, Jelisaveta Ignjatović, Tingting Liu, Meihua Han, Dongmei Cun, Jelena Đuriš, Mingshi Yang, Sandra Cvijić
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 16, Iss 3, Pp 350-362 (2021)
This study aims to understand the absorption patterns of three different kinds of inhaled formulations via in silico modeling using budesonide (BUD) as a model drug. The formulations investigated in this study are: (i) commercially available microniz
Externí odkaz:
https://doaj.org/article/5b6a4605693e409fa775b852e5033a50
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 14, Iss 2, Pp 183-192 (2019)
The aim of this study was to develop a palatable donepezil (DP) orodispersible film (ODF) to facilitate the swallowing process and investigate the effect of cyclodextrin on taste-masking based on dynamic process and in vivo drug absorption. Complexat
Externí odkaz:
https://doaj.org/article/406662aaea9348209dda5180e316206b
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 14, Iss 1, Pp 78-85 (2019)
Co-delivery of anti-cancer drugs is promising to improve the efficacy of cancer treatment. This study was aiming to investigate the potential of concurrent delivery of resveratrol (RES) and docetaxel (DTX) via polymeric nanocarriers to treat breast c
Externí odkaz:
https://doaj.org/article/492b8b9e1aa842c3a0b2195c5c7c3459
Autor:
Mengjun Zhang, Huiyang Jiang, Lan Wu, Haoyu Lu, Hriday Bera, Xing Zhao, Xiong Guo, Xulu Liu, Dongmei Cun, Mingshi Yang
Publikováno v:
Journal of Controlled Release. 352:422-437
With specific and inherent mRNA cleaving activity, small interfering RNA (siRNA) has been deemed promising therapeutics to reduce the exacerbation rate of asthma by inhibiting the expression and release of proinflammatory cytokines from airway epithe