Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Donglu Wu"'
Autor:
Shiwei Zhuang, Zhimei Liu, Jinyao Wu, Yudan Yao, Zongyang Li, Yanxiang Shen, Bin Yu, Donglu Wu
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 664 (2024)
The circulatory system is a closed conduit system throughout the body and consists of two parts as follows: the cardiovascular system and the lymphatic system. Hematological malignancies usually grow and multiply in the circulatory system, directly o
Externí odkaz:
https://doaj.org/article/b357fb8ddfcf4db29e3eec331b271e02
Autor:
Meiling Fan, Xintian Lan, Qunling Wang, Mengyao Shan, Xiaoxue Fang, Yegang Zhang, Donglu Wu, Haoming Luo, Wenyi Gao, Difu Zhu
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Nephropathy is a general term for kidney diseases, which refers to changes in the structure and function of the kidney caused by various factors, resulting in pathological damage to the kidney, abnormal blood or urine components, and other diseases.
Externí odkaz:
https://doaj.org/article/e867ce613998467997f7547f474b6e0e
Autor:
Lihan Mi, Meiling Fan, Tianjia Liu, Donglu Wu, Yang Wang, Fuqiang Li, Yong Cai, Zhidong Qiu, Da Liu, Lingling Cao
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Alzheimer’s disease (AD) is a serious public health issue but few drugs are currently available for the disease, and these only target the symptoms. It is well established that oxidative stress plays a crucial role in AD, and there is compelling ev
Externí odkaz:
https://doaj.org/article/cc80e74e16f6455ca24dd2c4d2e4e22c
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Breast cancer (BC) is one of the most common malignant tumor, the incidence of which has increased worldwide in recent years. Ginsenosides are the main active components of Panax ginseng C. A. Mey., in vitro and in vivo studies have confirmed that gi
Externí odkaz:
https://doaj.org/article/591e1ffe439c4b5bb1b56736cb4f8c7e
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
MicroRNAs are small non-coding RNAs that play important roles in gene regulation by influencing the translation and longevity of various target mRNAs and the expression of various target genes as well as by modifying histones and DNA methylation of p
Externí odkaz:
https://doaj.org/article/4f0d1f5da21e4bce8a40383ba594d77b
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Evidence for research over the past decade shows that epigenetic regulation mechanisms run through the development and prognosis of tumors. Therefore, small molecular compounds targeting epigenetic regulation have become a research hotspot in the dev
Externí odkaz:
https://doaj.org/article/fd3fb685ed1b4599973713e7b7dd37bf
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
One common and reversible type of post-translational modification (PTM) is the addition of O-linked β-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation), and its dynamic balance is controlled by O-GlcNAc transferase (OGT) and glycoside hy
Externí odkaz:
https://doaj.org/article/38425bee0ca44adaa628709620e2745f
Publikováno v:
Protein & Cell, Vol 8, Iss 10, Pp 713-723 (2017)
Abstract Dynamic changes of the post-translational O-GlcNAc modification (O-GlcNAcylation) are controlled by O-linked β-N-acetylglucosamine (O-GlcNAc) transferase (OGT) and the glycoside hydrolase O-GlcNAcase (OGA) in cells. O-GlcNAcylation often oc
Externí odkaz:
https://doaj.org/article/5caca5c104a94285a02274904dec74fb
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Coptis, a traditional medicinal plant, has been used widely in the field of traditional Chinese medicine for many years. More recently, the chemical composition and bioactivity of Coptis have been studied worldwide. Berberine is a main component of R
Externí odkaz:
https://doaj.org/article/1f6838f254d447e39b6f177bdf1f6d6e
Autor:
Da Liu, Donglu Wu, Linhong Zhao, Yang Yang, Jian Ding, Liguo Dong, Lianghai Hu, Fei Wang, Xiaoming Zhao, Yong Cai, Jingji Jin
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141014 (2015)
Histone post-translational modification heritably regulates gene expression involved in most cellular biological processes. Experimental studies suggest that alteration of histone modifications affects gene expression by changing chromatin structure,
Externí odkaz:
https://doaj.org/article/fdf92154138a4c3ca8480fb6f38d7415