Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Dongkyoo Park"'
Autor:
Ke Xu, Dongkyoo Park, Andrew T. Magis, Jun Zhang, Wei Zhou, Gabriel L. Sica, Suresh S. Ramalingam, Walter J. Curran, Xingming Deng
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-16 (2019)
Abstract Background Lung cancer patients with KRAS mutation(s) have a poor prognosis due in part to the development of resistance to currently available therapeutic interventions. Development of a new class of anticancer agents that directly targets
Externí odkaz:
https://doaj.org/article/3f768d5575f04b929f12a8fef492e1de
Autor:
Ke Xu, Dongkyoo Park, Andrew T. Magis, Jun Zhang, Wei Zhou, Gabriel L. Sica, Suresh S. Ramalingam, Walter J. Curran, Xingming Deng
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/f371963b104a416b8665cfeb2193aa6b
Publikováno v:
Bio-Protocol, Vol 6, Iss 22 (2016)
Patient-derived xenograft (PDX) models for cancer research have recently attracted considerable attention in both the academy and industry (Hidalgo et al., 2014; Wilding and Bodmer, 2014). PDX models have been developed from different tumor types inc
Externí odkaz:
https://doaj.org/article/f4a4758b33bc4053865623b3d2468f40
Publikováno v:
Genes, Vol 7, Iss 8, p 51 (2016)
The human cellular genome is under constant stress from extrinsic and intrinsic factors, which can lead to DNA damage and defective replication. In normal cells, DNA damage response (DDR) mediated by various checkpoints will either activate the DNA r
Externí odkaz:
https://doaj.org/article/0498c801d06f4538b555140ca1277d15
Autor:
Xingming Deng, Zhi-Qiang Xiao, Ya Cao, Gabriel L. Sica, Maohua Xie, Dongkyoo Park, Rui Li, Shuo You
PDF file - 218K, Ionizing radiation (IR) induces activation of the JAK2/STAT3/Bcl2/Bcl-XL survival signaling pathway in various human lung cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05beb452e95508abedf5c4f12d765674
https://doi.org/10.1158/1535-7163.22500037.v1
https://doi.org/10.1158/1535-7163.22500037.v1
Autor:
Xingming Deng, Zhi-Qiang Xiao, Ya Cao, Gabriel L. Sica, Maohua Xie, Dongkyoo Park, Rui Li, Shuo You
A major challenge affecting the outcomes of patients with lung cancer is the development of acquired radioresistance. However, the mechanisms underlying the development of resistance to therapy are not fully understood. Here, we discovered that ioniz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2336cd391f39fe839413d713044a7d
https://doi.org/10.1158/1535-7163.c.6536332.v1
https://doi.org/10.1158/1535-7163.c.6536332.v1
Autor:
Xingming Deng, Zhi-Qiang Xiao, Ya Cao, Gabriel L. Sica, Maohua Xie, Dongkyoo Park, Rui Li, Shuo You
PDF file - 74K, Niclosamide (Niclo) reduces STAT3 nuclear localization in radioresistant human lung cancer A549-IRR cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25581dbd94ec7ed360fe2756f6affe6c
https://doi.org/10.1158/1535-7163.22500034
https://doi.org/10.1158/1535-7163.22500034
Autor:
Xingming Deng, Zhi-Qiang Xiao, Ya Cao, Gabriel L. Sica, Maohua Xie, Dongkyoo Park, Rui Li, Shuo You
PDF file - 190K, Niclosamide increases the proportion of the cell population in the G0/G1 phase in A549 parental and radioresistant A549 (A549-IRR) cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851d9d7d14bd577ccb066ee3db2e18ce
https://doi.org/10.1158/1535-7163.22500031
https://doi.org/10.1158/1535-7163.22500031
Autor:
Xingming Deng, Zhi-Qiang Xiao, Ya Cao, Gabriel L. Sica, Maohua Xie, Dongkyoo Park, Rui Li, Shuo You
PDF file - 109K, Niclosamide-induced growth inhibition is diminished after specific knockdown of STAT3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694b265e6e15031c8292f5396c594969
https://doi.org/10.1158/1535-7163.22500028
https://doi.org/10.1158/1535-7163.22500028
Autor:
Xingming Deng, Zhi-Qiang Xiao, Ya Cao, Gabriel L. Sica, Maohua Xie, Dongkyoo Park, Rui Li, Shuo You
PDF file - 142K, Niclosamide or in combination with IR inhibits cell proliferation in tumor tissues.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1e38b9790302e98ef78c8c742d3b1a
https://doi.org/10.1158/1535-7163.22500025
https://doi.org/10.1158/1535-7163.22500025