Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dongkyeong Kim"'
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background Although genome-wide association studies (GWAS) have identified multiple regions conferring genetic risk for juvenile idiopathic arthritis (JIA), we are still faced with the task of identifying the single nucleotide polymorphisms
Externí odkaz:
https://doaj.org/article/098fccfca55a417aaff71d5905676db1
Publikováno v:
Human Molecular Genetics. 32:835-846
Olig2 is a basic helix–loop–helix transcription factor that plays a critical role in the central nervous system. It directs the specification of motor neurons and oligodendrocyte precursor cells (OPCs) from neural progenitors and the subsequent m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6413d879d00e7896326beac50e5b42
https://doi.org/10.1093/hmg/ddac249
https://doi.org/10.1093/hmg/ddac249
IntroductionAlthough genome-wide association studies (GWAS) multiple regions conferring genetic risk for juvenile idiopathic arthritis (JIA), we are still faced with the task of identifying the single nucleotide polymorphisms (SNPs) on the disease ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19d7b439e983881e5b6dec741ed74911
https://doi.org/10.1101/2022.03.07.483040
https://doi.org/10.1101/2022.03.07.483040
Publikováno v:
Life Science Alliance
Murine neural stem cell exosomes/microvesicles can work to reduce SARS-CoV-2, an effect that can be adaptively enhanced via viral RNA fragment stimulation, which requires the PIWI-piRNA system.
Murine neural stem cells (NSCs) were recently shown
Murine neural stem cells (NSCs) were recently shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7104bbcc65327fbc80b5961320b28489
https://pubmed.ncbi.nlm.nih.gov/34862272
https://pubmed.ncbi.nlm.nih.gov/34862272
Autor:
Hongjoo An, Randall S. Shearer, Dongkyeong Kim, Jin-ok Choi, Mohamed Sharif, Yungki Park, Sun Ryu, Chuandong Fan
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Mapping enhancers to genes is a fundamental goal of modern biology. We have developed an innovative strategy that maps enhancers to genes in a principled manner. We illustrate its power by applying it to Myrf. Despite being a master regulator of olig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07239240d0a0105b5bcbd672f837026
http://link.springer.com/article/10.1038/s41598-019-47521-w
http://link.springer.com/article/10.1038/s41598-019-47521-w
Publikováno v:
Hum Mol Genet
Oligodendrocytes (OLs) produce myelin in the central nervous system (CNS), which accelerates the propagation of action potentials and supports axonal integrity. As a major component of CNS myelin, proteolipid protein 1 (Plp1) is indispensable for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6756919d56ab67b5ce9bd02c0751e5b4
https://pubmed.ncbi.nlm.nih.gov/34230963
https://pubmed.ncbi.nlm.nih.gov/34230963
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Myrf is a membrane-bound transcription factor that plays a key role in various biological processes. The Intramolecular Chaperone Auto-processing (ICA) domain of Myrf forms a homo-trimer, which carries out the auto-cleavage of Myrf. The ICA homo-trim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655a21431ed57f53c0e8ad0de0e05557
https://doi.org/10.1038/s41598-020-57593-8
https://doi.org/10.1038/s41598-020-57593-8
Exosomes/microvesicles target SARS-CoV-2 via innate and RNA-induced immunity with PIWI-piRNA system.
Publikováno v:
Life Science Alliance; Mar2022, Vol. 5 Issue 3, p1-14, 14p
Autor:
Randall S. Shearer, Mohamed Sharif, Chuandong Fan, Patrick Busch, Yungki Park, Dongkyeong Kim, Jin-ok Choi
Publikováno v:
Nucleic Acids Research
Myrf is a key transcription factor for oligodendrocyte differentiation and central nervous system myelination. We and others have previously shown that Myrf is generated as a membrane protein in the endoplasmic reticulum (ER), and that it undergoes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0b7d406c693881faa45b1ace7d8779
https://doi.org/10.1093/nar/gkx080
https://doi.org/10.1093/nar/gkx080
Autor:
Yungki Park, Dongkyeong Kim
Publikováno v:
Human Molecular Genetics
Multiple sclerosis (MS) is known as an autoimmune demyelinating disease of the central nervous system. However, its cause remains elusive. Given previous studies suggesting that dysfunctional oligodendrocytes (OLs) may trigger MS, we tested whether s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6989b95941a875d789cd6f3067be2959
https://pubmed.ncbi.nlm.nih.gov/31509193
https://pubmed.ncbi.nlm.nih.gov/31509193