Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Dongkui Xu"'
Publikováno v:
Cancer Pathogenesis and Therapy, Vol 1, Iss 2, Pp 98-110 (2023)
Background: Colorectal cancer (CRC) is the third most common malignancy and the second deadliest cancer worldwide. Metastasis to the liver, the most common metastatic site in CRC, is the leading cause of death in patients with CRC. Hyperlipidemia, wh
Externí odkaz:
https://doaj.org/article/1fcc91aa14aa496aa276163e5471b1bb
Autor:
Ting Wang, Fangzhou Sun, Chunxiao Li, Peng Nan, Yan Song, Xuhao Wan, Hongnan Mo, Jinsong Wang, Yantong Zhou, Yuzheng Guo, Aya Ei Helali, Dongkui Xu, Qimin Zhan, Fei Ma, Haili Qian
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Liver metastasis is the most fatal event of colon cancer patients. Warburg effect has been long challenged by the fact of upregulated oxidative phosphorylation (OXPHOS), while its mechanism remains unclear. Here, metastasis‐associated anti
Externí odkaz:
https://doaj.org/article/bdf2ecd8f92847e89863a5ed9dd51dd1
Publikováno v:
BMJ Open, Vol 12, Iss 9 (2022)
Objectives Synergism between the metabolic syndrome (MetSyn) components and cancer incidence still remains inconclusive. We aimed to investigate the unique or joint role of MetSyn components in cancer onset.Design We conducted a prospective nested ca
Externí odkaz:
https://doaj.org/article/49406f6c05a64987a9236126f13278f8
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Nowadays, colorectal cancer (CRC) is one of the most commonly diagnosed malignant tumors worldwide, the incidence rate of which is still increasing year by year. Herein, the objective of this study is to investigate whether CDC42E
Externí odkaz:
https://doaj.org/article/146847cea94b4352bc3a52e6121c30df
Autor:
Yantong Zhou, Peng Nan, Chunxiao Li, Hongnan Mo, Ying Zhang, Haijuan Wang, Dongkui Xu, Fei Ma, Haili Qian
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundThe MTA1 protein encoded by metastasis-associated protein 1 (MTA1) is a key component of the ATP-dependent nucleosome remodeling and deacetylase (NuRD) complex, which is widely upregulated in cancers. MTA1 extensively affects downstream gen
Externí odkaz:
https://doaj.org/article/60f8e1d6ed8542928d452cb3acdbc6a8
Autor:
Jian Liu, Chunxiao Li, Jinsong Wang, Dongkui Xu, Haijuan Wang, Ting Wang, Lina Li, Hui Li, Peng Nan, Jingyao Zhang, Yang Wang, Changzhi Huang, Dong Chen, Yi Zhang, Tao Wen, Qimin Zhan, Fei Ma, Haili Qian
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Dsyregulation of mitosis-related alternative splicing in cancer cells is not well understood. Here, the authors show that cancer metastasis-associated antigen 1 (MTA1), an oncogenic chromatin associated protein, is an RNA-binding protein that regulat
Externí odkaz:
https://doaj.org/article/bb67f8189e5f4ff28d476b2b1f343150
Publikováno v:
Journal of International Medical Research, Vol 49 (2021)
Poorly differentiated gastric adenocarcinoma is commonly associated with lymph node metastasis, peritoneal spread, and liver metastasis but rarely with intraintestinal metastasis. Most patients with metastatic gastric carcinoma are unable to undergo
Externí odkaz:
https://doaj.org/article/032fd5987edf417a967fd3558041aae5
Publikováno v:
Clinical and Experimental Obstetrics & Gynecology, Vol 49, Iss 5, p 119 (2022)
Background: TNF-α has a wide range of functions in processes within the ovaries, including follicular development, ovarian hormones synthesis, ovulation, granulosa cell necroptosis, and follicular atresia. Innate immune response in the ovaries is th
Externí odkaz:
https://doaj.org/article/e69f7a5b259f4a77886f0da4bdb25bcb
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 115, Iss , Pp - (2019)
The current study was undertaken to investigate the potential influence of methylation on miR-362-5p/3p expression and further analyzed their independent prognostic value in cervical adenocarcinoma (ADC) and squamous cell carcinoma (SCC) respectively
Externí odkaz:
https://doaj.org/article/ddf8c7985ca945c2bddd7a9cc7f65e71
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163460 (2016)
Epigenetic modulation is an important mechanism of miRNA dysregulation in cervical cancer. In this study, we firstly studied how this mechanism contributes to miR-375 downregulation in cervical cancer cells. Then, we further studied the association b
Externí odkaz:
https://doaj.org/article/890666f8f2794273980a27f0228db86a