Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Dongjun Lin"'
Publikováno v:
Stem Cell Research, Vol 73, Iss , Pp 103230- (2023)
We have generated an iPSCs line (IPS-AML2-C3, SYSUSHi002-A) from AML cells of a 71-year-old male Acute Myeloid Leukaemia patient with TP53 gene mutation (TP53: c.824G > A, p.Cys275Tyr) using episomal plasmids encoding the factors OCT4, SOX2, KLF4, L-
Externí odkaz:
https://doaj.org/article/b6470a8b4f0a431ca73132cdfb9d20ff
Autor:
Hua Jin, Yu Zhang, Sijian Yu, Xin Du, Na Xu, Ruoyang Shao, Dongjun Lin, Yanqiu Chen, Jie Xiao, Zhiqiang Sun, Lan Deng, Xinquan Liang, Hongyu Zhang, Ziwen Guo, Min Dai, Pengcheng Shi, Fen Huang, Zhiping Fan, Zhao Yin, Li Xuan, Ren Lin, Xuejie Jiang, Guopan Yu, Qifa Liu
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Background Relapsed or refractory acute myeloid leukemia (R/R AML) has a dismal prognosis. The aim of this study was to investigate the activity and tolerability of venetoclax combined with azacitidine plus homoharringtonine (VAH) regimen fo
Externí odkaz:
https://doaj.org/article/82cc1f95a37248199c82f54e44313b2d
Autor:
Hongzhou Wang, Xiaodong Li, Cheng Tong, Yongkang Xu, Dongjun Lin, Jiazhi Wang, Fei Yao, Pengxuan Zhu, Guixia Yan
Publikováno v:
Frontiers in Environmental Science, Vol 11 (2023)
The wide application of the evapotranspiration (ET) products has deepened our understanding of the water, energy and carbon cycles, driving increased interest in regional and global assessments of their performance. However, evaluating ET products at
Externí odkaz:
https://doaj.org/article/c97f2388b5084cd1a2c1f9108ace2187
Autor:
Menglin Fan, Yu Wang, Ren Lin, Tong Lin, Fen Huang, Zhiping Fan, Yajing Xu, Ting Yang, Na Xu, Pengcheng Shi, Danian Nie, Dongjun Lin, Zujun Jiang, Shunqing Wang, Jing Sun, Xiaojun Huang, Qifa Liu, Li Xuan, Peng Lyu
Publikováno v:
Chinese Medical Journal, Vol 135, Iss 8, Pp 930-939 (2022)
Abstract. Background:. Compared with human leukocyte antigen (HLA)-matched sibling donor (MSD) transplantation, it remains unclear whether haploidentical donor (HID) transplantation has a superior graft-versus-leukemia (GVL) effect for Philadelphia-n
Externí odkaz:
https://doaj.org/article/bb7666c5bb1e4f5a98abd6c88d62c74b
Autor:
Ke Zhao, Ren Lin, Zhiping Fan, Xiaoyong Chen, Yu Wang, Fen Huang, Na Xu, Xi Zhang, Xin Zhang, Li Xuan, Shunqing Wang, Dongjun Lin, Lan Deng, Danian Nie, Jianyu Weng, Yonghua Li, Xiaohui Zhang, Yuhua Li, A. P. Xiang, Qifa Liu
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-13 (2022)
Abstract Background Steroid-resistant (SR) acute graft-versus-host disease (aGVHD) lacks standard second-line treatment. Mesenchymal stromal cells (MSCs) have potential efficacy in SR aGVHD. We aimed to assess the efficacy and safety of MSCs combined
Externí odkaz:
https://doaj.org/article/877e9012162b4a58bfaa69ce75747681
Autor:
Yunxin Zeng, Xinyu Zhang, Dongjun Lin, Xiaohui Feng, Yuye Liu, Zhengwen Fang, Weijian Zhang, Yu Chen, Meng Zhao, Jun Wu, Linjia Jiang
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-6 (2021)
Abstract The hypoxic microenvironment is presumed to be a sanctuary for myeloid leukemia cells that causes relapse following chemotherapy, but the underlying mechanism remains elusive. Using a zebrafish xenograft model, we observed that the hypoxic h
Externí odkaz:
https://doaj.org/article/396da4126a384433b841fd512a89988f
Autor:
Zhitao Ye, Yishan Li, Xiaobin Tian, Yan Wei, Yanhui Yu, Kaibin Lai, Keyue Yang, Zixuan Qiu, Jianqing Lin, Meng Zhao, Dongjun Lin, Xiaojun Xu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundCell metabolic reprogramming is a hallmark of tumor prognosis, and fatty acid metabolism (FAM) plays a crucial role in the tumor microenvironment (TME). However, the relationship between FAM, TME, and prognosis of acute myeloid leukemia (AM
Externí odkaz:
https://doaj.org/article/cb526dd4d19a4246ba232eee015dd7c9
Autor:
Sijian Yu, Fen Huang, Zhiping Fan, Li Xuan, Danian Nie, Yajing Xu, Ting Yang, Shunqing Wang, Zujun Jiang, Na Xu, Ren Lin, Jieyu Ye, Dongjun Lin, Jing Sun, Xiaojun Huang, Yu Wang, Qifa Liu
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-11 (2020)
Abstract Background Compared with HLA-matched sibling donor (MSD) transplant, the outcomes of haploidentical donor (HID) transplant for refractory acute leukemia need to be further explored. In this study, we compared the outcomes of HID with MSD for
Externí odkaz:
https://doaj.org/article/b7eb3fb6ab4e4baa9296638c969260d7
Publikováno v:
Atmosphere, Vol 14, Iss 2, p 302 (2023)
The surface soil moisture over the Qinghai–Tibet Plateau (QTP) has an important impact on the weather and climate of East Asia. Under climate warming, the imbalance of solid–liquid water of QTP has become a research hotspot, but the surface soil
Externí odkaz:
https://doaj.org/article/f1f25ab5e1a1438198998b3e28b01234
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Acute myeloid leukemia (AML) is an aggressive hematological malignancy with high relapse/refractory rate. Genetic and epigenetic abnormalities are driving factors for leukemogenesis. RUNX1 and RUNX2 from the Runt-related transcription factor (RUNX) f
Externí odkaz:
https://doaj.org/article/44c8a7269fe34e789e83d0698239d5a6