Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Donghyun Ka"'
Publikováno v:
Applied Biological Chemistry, Vol 66, Iss 1, Pp 1-9 (2023)
Abstract In bacteria and archaea, CRISPRs and Cas proteins constitute an adaptive immune system against invading foreign genetic materials, such as bacteriophages and plasmids. To counteract CRISPR-mediated immunity, bacteriophages encode anti-CRISPR
Externí odkaz:
https://doaj.org/article/a7e2d3468b82459086cc17ade3ed9d48
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
The Thoeris defense system is a recently discovered bacterial defense system that protects bacteria against phage infection and consists of the two genes thsA and thsB. Here, the authors present the crystal structures of Bacillus cereus ThsA and ThsB
Externí odkaz:
https://doaj.org/article/f8b6653fb2e144b0a1e0302ac32e58fb
Autor:
Donghyun Ka, Suji Hong, Ugeene Jeong, Migyeong Jeong, Nayoung Suh, Jeong-Yong Suh, Euiyoung Bae
Publikováno v:
Structural Dynamics, Vol 4, Iss 5, Pp 054701-054701-14 (2017)
Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins constitute a microbial, adaptive immune system countering invading nucleic acids. Cas2 is a universal Cas protein found in all types of CRISPR-Ca
Externí odkaz:
https://doaj.org/article/b735bc0dab6846c19f71546d8f73b3bd
Autor:
So Young An, Suji Hong, Euiyoung Bae, Donghyun Ka, Jasung Koo, Iktae Kim, Eun-Hee Kim, Jeong-Yong Suh
Publikováno v:
Nucleic Acids Research
The CRISPR–Cas system provides adaptive immunity for bacteria and archaea to combat invading phages and plasmids. Phages evolved anti-CRISPR (Acr) proteins to neutralize the host CRISPR–Cas immune system as a counter-defense mechanism. AcrIF7 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1154c052b563feb7938c52fac6a337f1
http://europepmc.org/articles/PMC7515697
http://europepmc.org/articles/PMC7515697
Autor:
Nak-Kyoon Kim, Jeong-Yong Suh, Euiyoung Bae, Donghyun Ka, Eun-Hee Kim, So Young An, Iktae Kim
Publikováno v:
Nucleic Acids Research
Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins provide adaptive immunity to prokaryotes against invading phages and plasmids. As a countermeasure, phages have evolved anti-CRISPR (Acr) protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cea8de274eb5184319401ffa3220cf7
http://europepmc.org/articles/PMC7367191
http://europepmc.org/articles/PMC7367191
Publikováno v:
Applied Sciences, Vol 14, Iss 21, p 9717 (2024)
Today, energy and performance efficiency have become a crucial factor in modern computing environments, such as high-end mobile devices, desktops, and enterprise servers, because data volumes in cloud datacenters increase exponentially. Unfortunately
Externí odkaz:
https://doaj.org/article/5b8306ab680141628223ff283c57ac00
Publikováno v:
Applied Sciences, Vol 14, Iss 19, p 8848 (2024)
In deep learning (DL) frameworks, a checkpoint operation is widely used to store intermediate variable values (e.g., weights, biases, and gradients) on storage media. This operation helps to reduce the recovery time of running a machine learning (ML)
Externí odkaz:
https://doaj.org/article/16c057c348a049c895bfb3cfb39149cb
Publikováno v:
Nucleic Acids Research
Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins provide microbial adaptive immunity against invading foreign nucleic acids. In type II-A CRISPR–Cas systems, the Cas1–Cas2 integrase complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d00a4e24654f669c4f15f150b70ea7a
https://doi.org/10.1093/nar/gky702
https://doi.org/10.1093/nar/gky702
Autor:
GoWoon Kim, Nak-Kyoon Kim, Jeong-Yong Suh, Kyoung-Seok Ryu, Euiyoung Bae, Migyeong Jeong, Donghyun Ka, Iktae Kim
Publikováno v:
FEBS Letters. 592:147-155
Cas2 protein in the CRISPR-Cas system functions as a scaffold for the acquisition of foreign DNA fragments, and as a nuclease against DNA and RNA substrates. Crystal structures of Cas2 have shown catalytically inactive conformational states that do n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e98b0fdbcf7ce0c77f65a642333281b
https://doi.org/10.1002/1873-3468.12942
https://doi.org/10.1002/1873-3468.12942
Publikováno v:
Nucleic Acids Research
Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins provide bacteria with RNA-based adaptive immunity against phage infection. To counteract this defense mechanism, phages evolved anti-CRISPR (Acr)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e8f8aef7528a114387a3e94bd48d33
http://europepmc.org/articles/PMC5758886
http://europepmc.org/articles/PMC5758886