Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Donghui Choe"'
Autor:
Donghui Choe, Connor A. Olson, Richard Szubin, Hannah Yang, Jaemin Sung, Adam M. Feist, Bernhard O. Palsson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Machine learning applied to large compendia of transcriptomic data has enabled the decomposition of bacterial transcriptomes to identify independently modulated sets of genes, such iModulons represent specific cellular functions. The identif
Externí odkaz:
https://doaj.org/article/29c8b485be004400aeb5b72816934259
Autor:
Jongoh Shin, Jung-Ran Noh, Donghui Choe, Namil Lee, Yoseb Song, Suhyung Cho, Eun-Jung Kang, Min-Jeong Go, Seok Kyun Ha, Jae-Hoon Kim, Yong-Hoon Kim, Kyoung-Shim Kim, Byoung-Chan Kim, Chul-Ho Lee, Byung-Kwan Cho
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-7 (2022)
Measurement(s) Microbiome Technology Type(s) Metagenome • Bacterial 16 S RNA Factor Type(s) Ageing • Co-housing • Parabiosis • Serum-injection • Akkermansia (AK) treatment Sample Characteristic - Organism Mus musculus Sample Characteristic
Externí odkaz:
https://doaj.org/article/09d67d58db4540abbfa8c39199f730f8
Autor:
Donghui Choe, Uigi Kim, Soonkyu Hwang, Sang Woo Seo, Donghyuk Kim, Suhyung Cho, Bernhard Palsson, Byung-Kwan Cho
Publikováno v:
mSystems, Vol 8, Iss 1 (2023)
ABSTRACT The massive sequencing of transposon insertion mutant libraries (Tn-Seq) represents a commonly used method to determine essential genes in bacteria. Using a hypersaturated transposon mutant library consisting of 400,096 unique Tn insertions,
Externí odkaz:
https://doaj.org/article/9b007b60c3e64bee9e5c517bb36f3e2a
Autor:
Jongoh Shin, Jung-Ran Noh, Donghui Choe, Namil Lee, Yoseb Song, Suhyung Cho, Eun-Jung Kang, Min-Jeong Go, Seok Kyun Ha, Dong-Ho Chang, Jae-Hoon Kim, Yong-Hoon Kim, Kyoung-Shim Kim, Haiyoung Jung, Myung Hee Kim, Bong-Hyun Sung, Seung-Goo Lee, Dae-Hee Lee, Byoung-Chan Kim, Chul-Ho Lee, Byung-Kwan Cho
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-19 (2021)
Abstract Background The gut microbiota is associated with diverse age-related disorders. Several rejuvenation methods, such as probiotic administration and faecal microbiota transplantation, have been applied to alter the gut microbiome and promote h
Externí odkaz:
https://doaj.org/article/e100ea10a9854f0aa228d02acc37e0b9
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2468-2476 (2021)
The market for using and storing digital data is growing, with DNA synthesis emerging as an efficient way to store massive amounts of data. Storing information in DNA mainly consists of two steps: data writing and reading. The writing step requires e
Externí odkaz:
https://doaj.org/article/e8f1adb0309d4cb5bee51cae2efe0e74
Autor:
Soonkyu Hwang, Namil Lee, Donghui Choe, Yongjae Lee, Woori Kim, Ji Hun Kim, Gahyeon Kim, Hyeseong Kim, Neung-Ho Ahn, Byoung-Hee Lee, Bernhard O. Palsson, Byung-Kwan Cho
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Bacteria belonging to Streptomyces have the ability to produce a wide range of secondary metabolites through a shift from primary to secondary metabolism regulated by complex networks activated after vegetative growth terminates. Despite considerable
Externí odkaz:
https://doaj.org/article/10b545a213614b2295b7c03234bae1f8
Autor:
Donghui Choe, Richard Szubin, Saugat Poudel, Anand Sastry, Yoseb Song, Yongjae Lee, Suhyung Cho, Bernhard Palsson, Byung-Kwan Cho
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009821 (2021)
RNA sequencing techniques have enabled the systematic elucidation of gene expression (RNA-Seq), transcription start sites (differential RNA-Seq), transcript 3' ends (Term-Seq), and post-transcriptional processes (ribosome profiling). The main challen
Externí odkaz:
https://doaj.org/article/0b37f4265fd34603afb9aa90ebbc369b
Autor:
Soonkyu Hwang, Namil Lee, Donghui Choe, Yongjae Lee, Woori Kim, Yujin Jeong, Suhyung Cho, Bernhard O. Palsson, Byung-Kwan Cho
Publikováno v:
mSystems, Vol 6, Iss 3 (2021)
Streptomyces
Externí odkaz:
https://doaj.org/article/8b587bfaddc543d2809c3bf3e3cd4d13
Autor:
Donghui Choe, Jun Hyoung Lee, Minseob Yoo, Soonkyu Hwang, Bong Hyun Sung, Suhyung Cho, Bernhard Palsson, Sun Chang Kim, Byung-Kwan Cho
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Genome-reduced bacteria often show impaired growth under laboratory conditions. Here the authors use adaptive laboratory evolution to optimise growth performance and show transcriptome and translatome-wide remodeling of the organism.
Externí odkaz:
https://doaj.org/article/5767dc044b0944219925d7b9428faa08
Autor:
Minjeong Kang, Kangsan Kim, Donghui Choe, Suhyung Cho, Sun Chang Kim, Bernhard Palsson, Byung-Kwan Cho
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Adaptive laboratory evolution (ALE) is used to find causal mutations that underlie improved strain performance under the applied selection pressure. ALE studies have revealed that mutator populations tend to outcompete their non-mutator counterparts
Externí odkaz:
https://doaj.org/article/3be3c6703abb4da997610be4bc680799