Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Donghuai Xiao"'
Autor:
Yingxin Lu, Danwen Sun, Donghuai Xiao, Yingying Shao, Mingbo Su, Yubo Zhou, Jia Li, Shulei Zhu, Wei Lu
Publikováno v:
Molecules, Vol 26, Iss 23, p 7241 (2021)
Histone deacetylases (HDACs) play important roles in cell growth, cell differentiation, cell apoptosis, and many other cellular processes. The inhibition of different classes of HDACs has been shown to be closely related to the therapy of cancers and
Externí odkaz:
https://doaj.org/article/d5e449ebe29b473cabf25b6033573f4f
Autor:
Shulei Zhu, Donghuai Xiao, Mingbo Su, Danwen Sun, Jia Li, Yingxin Lu, Wei Lu, Yubo Zhou, Ying-Ying Shao
Publikováno v:
Molecules, Vol 26, Iss 7241, p 7241 (2021)
Molecules
Molecules; Volume 26; Issue 23; Pages: 7241
Molecules
Molecules; Volume 26; Issue 23; Pages: 7241
Histone deacetylases (HDACs) play important roles in cell growth, cell differentiation, cell apoptosis, and many other cellular processes. The inhibition of different classes of HDACs has been shown to be closely related to the therapy of cancers and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852231fe1c0a861dc68cac26b58ccc50
https://www.mdpi.com/1420-3049/26/23/7241
https://www.mdpi.com/1420-3049/26/23/7241
Autor:
Shulei Zhu, Jieyu Liu, Donghuai Xiao, Peipei Wang, Jingkun Ma, Xiaobei Hu, Jingfeng Fu, Yubo Zhou, Jia Li, Wei Lu
Publikováno v:
European Journal of Medicinal Chemistry. 243:114786
Proteolysis targeting chimera (PROTAC) technology has received widespread attention in recent years as a promising strategy for drug development. Herein, we report a series of novel Wee1 degraders, which were designed and synthesized based on PROTAC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3df7e44688c4190231d6dd8f1bf725
https://doi.org/10.1016/j.ejmech.2022.114786
https://doi.org/10.1016/j.ejmech.2022.114786
Autor:
Yubo Zhou, Donghuai Xiao, Kan Weijuan, Wang Yujie, Wei Lu, Hu Xiaobei, Xuefeng Jiang, Qiumeng Zhang, Jia Li
Publikováno v:
European journal of medicinal chemistry. 176
Lenalidomide and its analogs have exhibited extensive anti-tumor, anti-inflammatory and immunomodulatory properties in pharmaceutical research. In this work, a series of novel thioether-containing lenalidomide analogs were designed and synthesized fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c14a100f8d1794cef7dcb31a004e2c1
https://pubmed.ncbi.nlm.nih.gov/31125896
https://pubmed.ncbi.nlm.nih.gov/31125896
Publikováno v:
Archiv der Pharmazie. 353:1900376
Lenalidomide is a cereblon modulator known for its antitumor, anti-inflammatory, and immunomodulatory properties in clinical applications. Recently, some reported lenalidomide analogs could exhibit a significant bioactivity through various modificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb4e9add81ae72c11720980f0fd18b0
https://doi.org/10.1002/ardp.201900376
https://doi.org/10.1002/ardp.201900376