Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Donghan M. Yang"'
Autor:
Jingwei Huang, Donghan M. Yang, Ruichen Rong, Kuroush Nezafati, Colin Treager, Zhikai Chi, Shidan Wang, Xian Cheng, Yujia Guo, Laura J. Klesse, Guanghua Xiao, Eric D. Peterson, Xiaowei Zhan, Yang Xie
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Existing natural language processing (NLP) methods to convert free-text clinical notes into structured data often require problem-specific annotations and model training. This study aims to evaluate ChatGPT’s capacity to extract informatio
Externí odkaz:
https://doaj.org/article/e549ab435ab1449ba0936dca3ae52846
Deep learning of cell spatial organizations identifies clinically relevant insights in tissue images
Autor:
Shidan Wang, Ruichen Rong, Qin Zhou, Donghan M. Yang, Xinyi Zhang, Xiaowei Zhan, Justin Bishop, Zhikai Chi, Clare J. Wilhelm, Siyuan Zhang, Curtis R. Pickering, Mark G. Kris, John Minna, Yang Xie, Guanghua Xiao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Recent advancements in tissue imaging techniques have facilitated the visualization and identification of various cell types within physiological and pathological contexts. Despite the emergence of cell-cell interaction studies, there is a l
Externí odkaz:
https://doaj.org/article/961e40ca5e004fd7933cd040aeea0ee3
Autor:
Ruichen Rong, Kristin Denton, Kevin W. Jin, Peiran Quan, Zhuoyu Wen, Julia Kozlitina, Stephen Lyon, Aileen Wang, Carol A. Wise, Bruce Beutler, Donghan M. Yang, Qiwei Li, Jonathan J. Rios, Guanghua Xiao
Publikováno v:
Bioengineering, Vol 11, Iss 7, p 670 (2024)
Genetic mouse models of skeletal abnormalities have demonstrated promise in the identification of phenotypes relevant to human skeletal diseases. Traditionally, phenotypes are assessed by manually examining radiographs, a tedious and potentially erro
Externí odkaz:
https://doaj.org/article/a8a5d6b9406040a982c0f988404ae091
Autor:
Anna Rogojina, Laura J. Klesse, Erin Butler, Jiwoong Kim, He Zhang, Xue Xiao, Lei Guo, Qinbo Zhou, Taylor Hartshorne, Dawn Garcia, Korri Weldon, Trevor Holland, Abhik Bandyopadhyay, Luz Perez Prado, Shidan Wang, Donghan M. Yang, Anne-Marie Langevan, Yi Zou, Allison C. Grimes, Chatchawin Assanasen, Vinod Gidvani-Diaz, Siyuan Zheng, Zhao Lai, Yidong Chen, Yang Xie, Gail E. Tomlinson, Stephen X. Skapek, Raushan T. Kurmasheva, Peter J. Houghton, Lin Xu
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108171- (2023)
Summary: Patient-derived xenografts (PDX) remain valuable models for understanding the biology and for developing novel therapeutics. To expand current PDX models of childhood leukemia, we have developed new PDX models from Hispanic patients, a subgr
Externí odkaz:
https://doaj.org/article/22cacf03f3b04f17bc8080bce501067f
Autor:
Shidan Wang, Ruichen Rong, Donghan M. Yang, Junya Fujimoto, Justin A. Bishop, Shirley Yan, Ling Cai, Carmen Behrens, Lynne D. Berry, Clare Wilhelm, Dara Aisner, Lynette Sholl, Bruce E. Johnson, David J. Kwiatkowski, Ignacio I. Wistuba, Paul A. Bunn Jr., John Minna, Guanghua Xiao, Mark G. Kris, Yang Xie
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 2 (2023)
Tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR) are effective for many patients with lung cancer with EGFR mutations. However, not all patients are responsive to EGFR TKIs, including even those harboring EGFR-sensi
Externí odkaz:
https://doaj.org/article/4e4ef4f0039849eba1811dda587ccb82
Autor:
Liuzhuo Zhang, Ruichen Rong, Qiwei Li, Donghan M. Yang, Bo Yao, Danni Luo, Xiong Zhang, Xianfeng Zhu, Jun Luo, Yongquan Liu, Xinyue Yang, Xiang Ji, Zhidong Liu, Yang Xie, Yan Sha, Zhimin Li, Guanghua Xiao
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract This study aims to develop an artificial intelligence (AI)-based model to assist radiologists in pneumoconiosis screening and staging using chest radiographs. The model, based on chest radiographs, was developed using a training cohort and v
Externí odkaz:
https://doaj.org/article/db1cc265bd9a4042b7367f6d6b28f345
Autor:
Shidan Wang, Tao Wang, Lin Yang, Donghan M. Yang, Junya Fujimoto, Faliu Yi, Xin Luo, Yikun Yang, Bo Yao, ShinYi Lin, Cesar Moran, Neda Kalhor, Annikka Weissferdt, John Minna, Yang Xie, Ignacio I. Wistuba, Yousheng Mao, Guanghua Xiao
Publikováno v:
EBioMedicine, Vol 50, Iss , Pp 103-110 (2019)
Background: The spatial distributions of different types of cells could reveal a cancer cell's growth pattern, its relationships with the tumor microenvironment and the immune response of the body, all of which represent key “hallmarks of cancer”
Externí odkaz:
https://doaj.org/article/b463a51364b84fa1b460a2894fa8bb21
Autor:
Xiaopeng He, Shen Yin, Hongyu Liu, Rong Lu, Kemp Kernstine, David E. Gerber, Yang Xie, Donghan M. Yang
Publikováno v:
Frontiers in Surgery, Vol 8 (2021)
Background: Current treatment guidelines for stage IV non-small cell lung cancer (NSCLC) with brain metastases recommend brain treatments, including surgical resection and radiotherapy (RT), in addition to resection of the primary lung tumor. Here, w
Externí odkaz:
https://doaj.org/article/3e36cb4a6ce54e599fef9d472ca53e04
Autor:
Ruichen Rong, Shidan Wang, Xinyi Zhang, Zhuoyu Wen, Xian Cheng, Liwei Jia, Donghan M. Yang, Yang Xie, Xiaowei Zhan, Guanghua Xiao
Publikováno v:
The American Journal of Pathology. 193:404-416
Autor:
Zhuoyu Wen, Shidan Wang, Donghan M. Yang, Yang Xie, Mingyi Chen, Justin Bishop, Guanghua Xiao
Publikováno v:
Seminars in Diagnostic Pathology. 40:109-119