Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Donggi, Paik"'
Autor:
Jinzhi Duan, Juan D. Matute, Lukas W. Unger, Thomas Hanley, Alexandra Schnell, Xi Lin, Niklas Krupka, Paul Griebel, Conner Lambden, Brandon Sit, Joep Grootjans, Michal Pyzik, Felix Sommer, Sina Kaiser, Maren Falk-Paulsen, Helmut Grasberger, John Y. Kao, Tobias Fuhrer, Hai Li, Donggi Paik, Yunjin Lee, Samuel Refetoff, Jonathan N. Glickman, Adrienne W. Paton, Lynn Bry, James C. Paton, Uwe Sauer, Andrew J. Macpherson, Philip Rosenstiel, Vijay K. Kuchroo, Matthew K. Waldor, Jun R. Huh, Arthur Kaser, Richard S. Blumberg
Publikováno v:
Immunity, 56(5), 1115-1131.e9. Cell Press
Intestinal IL-17-producing T helper (Th17) cells are dependent on adherent microbes in the gut for their development. However, how microbial adherence to intestinal epithelial cells (IECs) promotes Th17 cell differentiation remains enigmatic. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcd3323c2cd92a9cd5fa93839796145
Autor:
Donggi Paik, Lina Yao, Yancong Zhang, Sena Bae, Gabriel D. D’Agostino, Minghao Zhang, Eunha Kim, Eric A. Franzosa, Julian Avila-Pacheco, Jordan E. Bisanz, Christopher K. Rakowski, Hera Vlamakis, Ramnik J. Xavier, Peter J. Turnbaugh, Randy S. Longman, Michael R. Krout, Clary B. Clish, Fraydoon Rastinejad, Curtis Huttenhower, Jun R. Huh, A. Sloan Devlin
Publikováno v:
Nature
The microbiota modulates gut immune homeostasis. Bacteria influence the development and function of host immune cells, including T helper cells expressing interleukin-17A (T(H)17 cells). We previously reported that the bile acid (BA) metabolite 3-oxo
Autor:
Ravi Bharadwaj, Christina F. Lusi, Siavash Mashayekh, Abhinit Nagar, Malireddi Subbarao, Griffin I. Kane, Kimberly Wodzanowski, Ashley Brown, Kendi Okuda, Amanda Monahan, Donggi Paik, Anubhab Nandy, Madison Anonick, William E. Goldman, Thirumala-Devi Kanneganti, Megan H. Orzalli, Catherine Leimkuhler Grimes, Prabhani U. Atukorale, Neal Silverman
SummaryCytosolic innate immune sensing is critical for protecting barrier tissues. NOD1 and NOD2 are cytosolic sensors of small peptidoglycan fragments (muropeptides) derived from the bacterial cell wall. These muropeptides enter cells, especially ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f06a72355307ae7569241110405574d
https://doi.org/10.1101/2022.09.29.509906
https://doi.org/10.1101/2022.09.29.509906
Autor:
Ravi Bharadwaj, Christina F. Lusi, Siavash Mashayekh, Abhinit Nagar, Malireddi Subbarao, Griffin I. Kane, Kimberly A. Wodzanowski, Ashley R. Brown, Kendi Okuda, Amanda Monahan, Donggi Paik, Anubhab Nandy, Madison V. Anonick, William E. Goldman, Thirumala-Devi Kanneganti, Megan H. Orzalli, Catherine Leimkuhler Grimes, Prabhani U. Atukorale, Neal Silverman
Publikováno v:
Immunity. 56:998-1012.e8
Autor:
Eunha Kim, Donggi Paik, Ricardo N. Ramirez, Delaney G. Biggs, Youngjun Park, Ho-Keun Kwon, Gloria B. Choi, Jun R. Huh
Publikováno v:
Immunity
Children with autism spectrum disorders often display dysregulated immune responses and related gastrointestinal symptoms. However, the underlying mechanisms leading to the development of both phenotypes have not been elucidated. Here, we showed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1546cdf19dadb50cb0487e68535c02a5
https://europepmc.org/articles/PMC8755621/
https://europepmc.org/articles/PMC8755621/
Autor:
A. Sloan Devlin, Clary B. Clish, Randy S. Longman, Christopher K. Rakowski, Gabriel D. D’Agostino, Eunha Kim, Julian Avila-Pacheco, Peter J. Turnbaugh, Michael R. Krout, Jun R. Huh, Sena Bae, Hera Vlamakis, Ramnik J. Xavier, Donggi Paik, Eric A. Franzosa, Yancong Zhang, Lina Yao, Jordan E. Bisanz, Curtis Huttenhower
The microbiota plays a pivotal role in gut immune homeostasis. Bacteria influence the development and function of host immune cells, including T helper cells expressing interleukin-17a (TH17 cells). We previously reported that the bile acid metabolit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::648626da8ec6bb0afee511e2627766f3
https://doi.org/10.1101/2021.01.08.425913
https://doi.org/10.1101/2021.01.08.425913
Autor:
Donggi, Paik, Lina, Yao, Yancong, Zhang, Sena, Bae, Gabriel D, D'Agostino, Minghao, Zhang, Eunha, Kim, Eric A, Franzosa, Julian, Avila-Pacheco, Jordan E, Bisanz, Christopher K, Rakowski, Hera, Vlamakis, Ramnik J, Xavier, Peter J, Turnbaugh, Randy S, Longman, Michael R, Krout, Clary B, Clish, Fraydoon, Rastinejad, Curtis, Huttenhower, Jun R, Huh, A Sloan, Devlin
Publikováno v:
Nature. 603(7903)
The microbiota modulates gut immune homeostasis. Bacteria influence the development and function of host immune cells, including T helper cells expressing interleukin-17A (T
Autor:
Ashley H. Vernon, Donggi Paik, Scott T. Weiss, David A. Harris, Jun R. Huh, Hassan Aliakbarian, Ayşe Kılıç, Renuka Subramaniam, A. Sloan Devlin, Eric G. Sheu, Arijit A. Adhikari, Snehal N. Chaudhari, Lina Yao, James N. Luo
Publikováno v:
Cell hostmicrobe. 29(3)
Bariatric surgery is the most effective treatment for type 2 diabetes and is associated with changes in gut metabolites. Previous work uncovered a gut-restricted TGR5 agonist with anti-diabetic properties-cholic acid-7-sulfate (CA7S)-that is elevated
Autor:
Michael A. Fischbach, Ye Zheng, Lina Yao, Jun R. Huh, Fraydoon Rastinejad, A. Sloan Devlin, Samantha P. Kelly, Dan R. Littman, Jingping Lu, Randy S. Longman, Saiyu Hang, Eunha Kim, Soyoung Ha, Donggi Paik, Michael R. Krout, Brandon N. Nelson, Jamma Trinath, Lin Wu
Bile acids are abundant in the mammalian gut, where they undergo bacteria-mediated transformation to generate a large pool of bioactive molecules. Although bile acids are known to affect host metabolism, cancer progression and innate immunity, it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e6ca6e8892e89ae36b99e90f5f6de3
https://doi.org/10.1038/s41586-019-1785-z
https://doi.org/10.1038/s41586-019-1785-z
Autor:
Saiyu, Hang, Donggi, Paik, Lina, Yao, Eunha, Kim, Jamma, Trinath, Jingping, Lu, Soyoung, Ha, Brandon N, Nelson, Samantha P, Kelly, Lin, Wu, Ye, Zheng, Randy S, Longman, Fraydoon, Rastinejad, A Sloan, Devlin, Michael R, Krout, Michael A, Fischbach, Dan R, Littman, Jun R, Huh
Publikováno v:
Nature
Bile acids are abundant in the mammalian gut where they undergo bacteria-mediated transformation, generating a large pool of bioactive molecules. Although bile acids are known to affect host metabolism, cancer progression and innate immunity, it is u