Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Dongdi Li"'
Autor:
Deyun Qiu, Jinxin V. Pei, James E. O. Rosling, Vandana Thathy, Dongdi Li, Yi Xue, John D. Tanner, Jocelyn Sietsma Penington, Yi Tong Vincent Aw, Jessica Yi Han Aw, Guoyue Xu, Abhai K. Tripathi, Nina F. Gnadig, Tomas Yeo, Kate J. Fairhurst, Barbara H. Stokes, James M. Murithi, Krittikorn Kümpornsin, Heath Hasemer, Adelaide S. M. Dennis, Melanie C. Ridgway, Esther K. Schmitt, Judith Straimer, Anthony T. Papenfuss, Marcus C. S. Lee, Ben Corry, Photini Sinnis, David A. Fidock, Giel G. van Dooren, Kiaran Kirk, Adele M. Lehane
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
In a recent clinical trial for oral administration of cipargamin in individuals with malaria, there was an emergence of recrudescent parasites with a G358S mutation in PfATP4. In this work, the authors investigate the effect of this mutation on the f
Externí odkaz:
https://doaj.org/article/7abacde286514d8b929ffa3fbc4d3a0f
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 14, Iss C, Pp 341-349 (2016)
Membrane fatty acid desaturases are a diverse superfamily of enzymes that catalyze the introduction of double bonds into fatty acids. They are essential in a range of metabolic processes, such as the production of omega-3 fatty acids. However, our st
Externí odkaz:
https://doaj.org/article/df3d91aad97345059a23f3580d3227c8
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107162 (2014)
This study aimed to investigate the virological status in liver (both tumor and adjacent non-tumor tissue), the clinical features and the contribution of occult HBV infection (OBI) to postoperative prognosis in HBeAg-negative(-) hepatocellular carcin
Externí odkaz:
https://doaj.org/article/38a773dcdcc645cbb8a83ed8c21b089e
Autor:
Colin J. Jackson, James Robertson Petrie, Thomas Vanhercke, Dongdi Li, Adam M. Damry, Surinder P. Singh
Publikováno v:
Biochemistry. 59:1398-1409
Marine algae are a major source of ω-3 long-chain polyunsaturated fatty acids (ω3-LCPUFAs), which are conditionally essential nutrients in humans and a target for industrial production. The biosynthesis of these molecules in marine algae requires t
Autor:
Deyun Qiu, Jinxin V. Pei, James E. O. Rosling, Dongdi Li, Yi Xue, Jocelyn Sietsma Penington, Krittikorn Kümpornsin, Yi Tong Vincent Aw, Jessica Yi Han Aw, Heath Hasemer, Adelaide S. M. Dennis, Melanie C. Ridgway, Anthony T. Papenfuss, Marcus C. S. Lee, Giel G. van Dooren, Kiaran Kirk, Adele M. Lehane
Small-molecule inhibitors of PfATP4, a Plasmodium falciparum protein that is believed to pump Na+ out of the parasite while importing H+, are on track to become much-needed new antimalarial drugs. The spiroindolone cipargamin is poised to become the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60fbce80d8893b9d3de3dceeed4f1978
https://doi.org/10.1101/2022.01.11.475938
https://doi.org/10.1101/2022.01.11.475938
Autor:
Xueru Wang, Kanglei Zhang, Waseem Ali, Jiahui Li, Qing Huang, Dongdi Liu, Gang Liu, Di Ran, Zongping Liu
Publikováno v:
Poultry Science, Vol 103, Iss 7, Pp 103817- (2024)
Cadmium (Cd) is a common environmental pollutant associated with an increased incidence of renal metabolic diseases. Luteolin (Lut), a natural flavonoid, is widely used for its multifaceted therapeutic properties in inflammatory diseases. However, wh
Externí odkaz:
https://doaj.org/article/9d9dfb46110d4ed59b8aa7a2c22d4805
Autor:
Dongdi Li, Farid Rahimi, Katherine O. Bray, Adelaide S. M. Dennis, Kiaran Kirk, Christopher J. Tonkin, Adele M. Lehane, Giel G. van Dooren, Hillary M. McArthur, Markus Winterberg, Esther Rajendran, James M. McCoy
The Plasmodium falciparum ATPase PfATP4 is the target of a diverse range of antimalarial compounds, including the clinical drug candidate cipargamin. PfATP4 was originally annotated as a Ca2+ transporter, but recent evidence suggests that it is a Na+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c8f2bca6ccf2513a50523e53615ecb
https://doi.org/10.1074/jbc.ra118.006706
https://doi.org/10.1074/jbc.ra118.006706
Autor:
Jan Schröder, Leonard J. Foster, Nichollas E. Scott, Anthony T. Papenfuss, Alessandro D. Uboldi, Adele M. Lehane, Christopher J. Tonkin, James M. McCoy, Dongdi Li, Rebecca Stewart
Toxoplasma gondii, like all apicomplexan parasites, uses Ca2+ signaling pathways to activate gliding motility to power tissue dissemination and host cell invasion and egress. A group of "plant-like" Ca2+-dependent protein kinases (CDPKs) transduces c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b7e5f92af7f1d759dd269e1edbc0ac
https://europepmc.org/articles/PMC5418062/
https://europepmc.org/articles/PMC5418062/
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107162 (2014)
PLoS ONE
PLoS ONE
This study aimed to investigate the virological status in liver (both tumor and adjacent non-tumor tissue), the clinical features and the contribution of occult HBV infection (OBI) to postoperative prognosis in HBeAg-negative(-) hepatocellular carcin
Autor:
Lehane, Adele M.1 adele.lehane@anu.edu.au, Dennis, Adelaide S. M.1, Bray, Katherine O.1, Dongdi Li1, Rajendran, Esther1, McCoy, James M.2,3, McArthur, Hillary M.1, Winterberg, Markus1, Rahimi, Farid1, Tonkin, Christopher J.2,3, Kirk, Kiaran1 kiaran.kirk@anu.edu.au, van Dooren, Giel G.1 giel.vandooren@anu.edu.au
Publikováno v:
Journal of Biological Chemistry. 4/5/2019, Vol. 294 Issue 14, p5720-5734. 15p.