Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Dongchao Lu"'
Autor:
Ke Xiao, Dongchao Lu, Jeannine Hoepfner, Laura Santer, Shashi Gupta, Angelika Pfanne, Sabrina Thum, Malte Lenders, Eva Brand, Peter Nordbeck, Thomas Thum
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Fabry disease is an X-linked deficiency of the lysosomal hydrolase alpha-galactosidase A (alpha-Gal). This results in an accumulation of globotriaosylceramide (GL-3/Gb3) in a variety of cells with subsequent functional impairment. The contin
Externí odkaz:
https://doaj.org/article/875154d0910d4335b4c8cf600b0c2de4
Autor:
Yihua Bei, Dongchao Lu, Christian Bär, Shambhabi Chatterjee, Alessia Costa, Isabelle Riedel, Frank C. Mooren, Yujiao Zhu, Zhenzhen Huang, Meng Wei, Meiyu Hu, Sunyi Liu, Pujiao Yu, Kun Wang, Thomas Thum, Junjie Xiao
Publikováno v:
Mol Ther
Exercise and its regulated molecules have myocardial protective effects against cardiac ischemia/reperfusion (I/R) injury. The muscle-enriched miR-486 was previously identified to be upregulated in the exercised heart, which prompted us to investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b870f415ae170196e32ab03e437fcd6d
https://doi.org/10.1016/j.ymthe.2022.01.031
https://doi.org/10.1016/j.ymthe.2022.01.031
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789811956416
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b567a2f404b66af57d2505b8efbdb8f
https://doi.org/10.1007/978-981-19-5642-3_16
https://doi.org/10.1007/978-981-19-5642-3_16
Publikováno v:
Advances in experimental medicine and biology. 1396
Cardiovascular diseases (CVDs) are the leading causes of death globally and urgently require new novel therapeutic strategies. Gene therapy is the application of gene modulation technology to treat abnormal gene expression under disease conditions. V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8af398a26317ae4c863dd8bc460363a8
https://pubmed.ncbi.nlm.nih.gov/36454471
https://pubmed.ncbi.nlm.nih.gov/36454471
Autor:
Sarah Cushman, Arne Schmidt, Ke Xiao, Dongchao Lu, Cheng-Kai Huang, Naisam Abbas, Christian Bär, Thomas Thum
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:59-60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afeecaf2143b2a4038823ad7a1358eca
https://doi.org/10.1016/j.yjmcc.2022.08.117
https://doi.org/10.1016/j.yjmcc.2022.08.117
Autor:
Sarah Cushman, Arne Schmidt, Dongchao Lu, Ke Xiao, Cheng-Kai Huang, Naisam Abbas, Thomas Thum, Christian Baer
Publikováno v:
Circulation Research. 131
Introduction: A subtype of non-coding RNA, circular RNAs (circRNAs), formed through backsplicing, are emerging as important regulators of cardiac development and cardiovascular diseases. CircRNAs are known to regulate gene expression through a multit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cdfb8a943b23d92fc82466912105a7a
https://doi.org/10.1161/res.131.suppl_1.p2063
https://doi.org/10.1161/res.131.suppl_1.p2063
Autor:
Yibin Wang, Shambhabi Chatterjee, Roger Foo, Ke Xiao, Dongchao Lu, Thomas Thum, Isabelle Riedel, Christian Bär
Publikováno v:
Journal of Molecular and Cellular Cardiology
The World Health Organization (WHO) declared coronavirus disease 2019 (COVID-19) as a public health emergency of international concern as more than 15 million cases were reported by 24th July 2020. Angiotensin-converting enzyme 2 (ACE2) is a COVID-19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444714f2c41146e2ed53d4720299cb6e
http://europepmc.org/articles/PMC7470794
http://europepmc.org/articles/PMC7470794
Autor:
Ariana Foinquinos, Hannah J. Hunkler, Julia Leonardy, Kumarswamy Regalla, Thomas Thum, Stefan Engelhardt, Dongchao Lu, Christian Bär, Kevin Schmidt, Ke Xiao, Jeannine Hoepfner, Sinje Biß, Deepak Ramanujam
Publikováno v:
Mol Ther
Physiological and pathological cardiovascular processes are tightly regulated by several cellular mechanisms. Non-coding RNAs, including long non-coding RNAs (lncRNAs), represent one important class of molecules involved in regulatory processes withi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db86b035730ae513030207654472331d
https://europepmc.org/articles/PMC8899598/
https://europepmc.org/articles/PMC8899598/
Autor:
Shashi Kumar Gupta, Emiliano Bolesani, Thomas Thum, Shambhabi Chatterjee, Katrin Streckfuss-Bömeke, Alessia Costa, Christian Bär, Diego Megias, Dongchao Lu, Sandor Batkai, Christina Brandenberger, Teresa Hofer, Robert Zweigerdt
Publikováno v:
Molecular Therapy
Mol Ther
Mol Ther
Doxorubicin is one of the most potent chemotherapeutic agents. However, its clinical use is restricted due to the severe risk of cardiotoxicity, partially attributed to elevated production of reactive oxygen species (ROS). Telomerase canonically main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0b903eea91b1502be49b6336b111f9
Autor:
Angelika Pfanne, Malte Lenders, Shashi Kumar Gupta, Sabrina Thum, Peter Nordbeck, Dongchao Lu, Thomas Thum, Jeannine Hoepfner, Eva Brand, Laura Santer, Ke Xiao
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Fabry disease is an X-linked deficiency of the lysosomal hydrolase alpha-galactosidase A (alpha-Gal). This results in an accumulation of globotriaosylceramide (GL-3/Gb3) in a variety of cells with subsequent functional impairment. The continuous prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4c08dc17ac8b6ce6b03339bcea0518
http://europepmc.org/articles/PMC6813291
http://europepmc.org/articles/PMC6813291