Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Dongbo Lu"'
Autor:
Zifeng Dai, Jingwei Li, Ying Li, Rui Wang, Huili Yan, Ziyu Xiong, Shiting Wu, Xi Yang, Dongbo Lu, Dongdong Zhang, Guofu Li, Yuwen Wang, Chunyang Men, Wenzhong Du, Xiangjian Zheng, Changbin Shi
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105642- (2022)
Summary: Cerebral cavernous malformation (CCM) is caused by loss-of-function mutations in CCM1, CCM2, or CCM3 genes of endothelial cells. It is characterized by pericyte deficiency. However, the role of pericytes in CCMs is not yet clarified. We foun
Externí odkaz:
https://doaj.org/article/560453f44d114a23ace36ac49856843b
Autor:
Dongbo Lu, Caroline A. Foley, Shama V. Birla, Austin J. Hepperla, Jeremy M. Simon, Lindsey I. James, Nathaniel A. Hathaway
Publikováno v:
ACS Synth Biol
CRISPR-Cas9 systems have been developed to regulate gene expression by using either fusions to epigenetic regulators or, more recently, through the use of chemically mediated strategies. These approaches have armed researchers with new tools to exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f131191e19babd90ec97027927d87704
https://doi.org/10.1021/acssynbio.1c00606
https://doi.org/10.1021/acssynbio.1c00606
Autor:
Maolin Xiong, Dandan Liang, Xiaoyu He, Jinzhu Zhuang, Fulei Zhang, Li Li, Yi Liu, Yi-Han Chen, Yahan Wu, Ran Duan, Ke Xiong, Dongbo Lu, Hongyu Liu, Liping Zhou, Huixing Zhou
Publikováno v:
Cell Res
The adult mammalian heart is thought to be a terminally differentiated organ given the postmitotic nature of cardiomyocytes. Consequently, the potential for cardiac repair through cardiomyocyte proliferation is extremely limited. Low-density lipoprot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64cd97c890bbb046cdd333e7a4c4f7c3
https://doi.org/10.1038/s41422-020-00411-7
https://doi.org/10.1038/s41422-020-00411-7
Autor:
Dongbo Lu1, Yu Chen1, Shan Liu1, Chao Guo2, Xia Li2,3 xbmeng@bjmu.edu.cn, Zhongjun Li1, Xiangbao Meng1 xiali@sdu.edu.cn
Publikováno v:
Journal of Chinese Pharmaceutical Sciences. Nov2019, Vol. 28 Issue 11, p786-801. 16p.
Autor:
Jian Jin, Dongbo Lu, Anna M. Chiarella, Xufen Yu, Silvia Pomella, Kyle V. Butler, Berkley E. Gryder, Nathaniel A. Hathaway, Tiffany A. Wang, Javed Khan
Publikováno v:
Nature biotechnology
Gene expression can be activated or suppressed using CRISPR–Cas9 systems. However, tools that enable dose-dependent activation of gene expression without the use of exogenous transcription regulatory proteins are lacking. Here we describe chemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7659198c475b74db00d2132fb0b280
http://europepmc.org/articles/PMC6954327
http://europepmc.org/articles/PMC6954327
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 943 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Proper regulation of the chromatin landscape is essential for maintaining eukaryotic cell identity and diverse cellular processes. The importance of the epigenome comes, in part, from the ability to influence gene expression through patterns in DNA m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b71c6de15b286def009fe9108773fdb3
https://www.mdpi.com/1422-0067/21/3/943
https://www.mdpi.com/1422-0067/21/3/943
Autor:
Xiangbao Meng, Shanshan Zhou, Zhongjun Li, Siwang Yu, Liyan Ji, Simin Yang, Jun Yang, Dongbo Lu
Publikováno v:
European Journal of Medicinal Chemistry. 122:488-496
A series of benzenesulfonamide derivatives were synthesized and evaluated for their anti-proliferative activity and interaction with tubulin. These new derivatives showed significant activities against cellular proliferative and tubulin polymerizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3404ca1441262ebf04fc2194ef7ab0af
https://doi.org/10.1016/j.ejmech.2016.07.002
https://doi.org/10.1016/j.ejmech.2016.07.002
Publikováno v:
International journal of radiation biology. 89(5)
The present study was conducted to investigate the effect of a temporally incoherent ('noise') magnetic field (MF) on radiofrequency radiation (RFR)-induced epidermal growth factor (EGF) receptor clustering and phosporylation in cultured cells.Human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2f3232aa096251630437332920e569
https://pubmed.ncbi.nlm.nih.gov/23210629
https://pubmed.ncbi.nlm.nih.gov/23210629
Publikováno v:
International journal of radiation biology. 88(3)
Many studies have shown that exposure to radiofrequency radiation (RFR) could activate cellular signal transduction pathways. In the present research, we investigated the effects of exposure to a 1.8-GHz RFR at different intensities on epidermal grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae544bb8f602185e9abd9b693549c46
https://pubmed.ncbi.nlm.nih.gov/22032630
https://pubmed.ncbi.nlm.nih.gov/22032630