Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Dong-yuan Chang"'
Publikováno v:
Journal of Diabetes, Vol 14, Iss 4, Pp 291-297 (2022)
Abstract Background Although extensive efforts have been paid to identify reliable predictors for renal outcomes of diabetic kidney disease (DKD) patients in type 2 diabetes mellitus (T2DM), there are still only a limited number of predictive factors
Externí odkaz:
https://doaj.org/article/e76babc954d647fda9a69f7e81d9e1c8
Publikováno v:
JCI Insight, Vol 7, Iss 24 (2023)
Accumulating evidence suggests the pathogenic role of immunity and metabolism in diabetic kidney disease (DKD). Herein, we aimed to investigate the effect of complement factor B (CFB) on lipid metabolism in the development of DKD. We found that in pa
Externí odkaz:
https://doaj.org/article/e8b714291f2a454bbe812a9e359c1a70
Publikováno v:
Chinese Medical Journal, Vol 134, Iss 17, Pp 2073-2080 (2021)
Abstract. Background:. Whether there is an association between serum uric acid (SUA) level and risk of mortality in the general population remains unclear. Based on the China National Survey of Chronic Kidney Disease linked to mortality data, a popul
Externí odkaz:
https://doaj.org/article/0d2fe29820eb4d8288c23d0bdf2d4414
Autor:
Zi-Jun Sun, Jin-Wei Wang, Dong-Yuan Chang, Shuo-Hua Chen, Hui-Fen Zhang, Shou-Ling Wu, Kevin He, Lu-Xia Zhang, Min Chen, Ming-Hui Zhao
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-10 (2020)
Abstract Background The association between blood pressure change and kidney damage in patients with abnormal blood glucose remains unclear. The current study aimed to identify systolic blood pressure (SBP) trajectories among the prediabetic populati
Externí odkaz:
https://doaj.org/article/c330e5f2ab9747a5bb296f7aeddaa7d9
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Sodium-glucose cotransporter 2(SGLT2) inhibitors show prominent renal protective effect in diabetic kidney disease (DKD), anti-inflammatory effect being one of its key mechanisms. Over-activation of the complement system, a crucial part of innate imm
Externí odkaz:
https://doaj.org/article/7e654422f0a1407e8e1118e4c7b40110
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
IntroductionAs the most common complication of diabetes mellitus (DM), diabetic nephropathy (DN) was initially considered to begin with proteinuria preceding the progression of renal insufficiency. This clinical paradigm has been questioned in the la
Externí odkaz:
https://doaj.org/article/cbdad821592e4f3592583adada078ebf
Publikováno v:
BMC Nephrology, Vol 18, Iss 1, Pp 1-9 (2017)
Abstract Background Whether persistent hematuria in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) during clinical remission reflects active disease or chronic glomerular injury is uncertain. This study aimed to
Externí odkaz:
https://doaj.org/article/2bc3a855354349c49966f02fa789d3eb
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-11 (2017)
Abstract Background Our previous study found that circulating and urinary levels of high mobility group box-1 (HMGB1) were closely associated with disease activity in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV
Externí odkaz:
https://doaj.org/article/f1218ead77484e87886ba561f5e77709
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123586 (2015)
BackgroundHigh mobility group box-1 (HMGB1), a kind of pro-inflammatory mediator, is associated with inflammatory conditions and tissue damage. Our previous study demonstrated that the circulating levels of HMGB1 correlated with disease activity of a
Externí odkaz:
https://doaj.org/article/28ae815e105849e4947ad5a0d59a42f6
Autor:
Jiahao, Liu, Viji, Nair, Yi-Yang, Zhao, Dong-Yuan, Chang, Christine, Limonte, Nisha, Bansal, Damian, Fermin, Felix, Eichinger, Emily C, Tanner, Keith A, Bellovich, Susan, Steigerwalt, Zeenat, Bhat, Jennifer J, Hawkins, Lalita, Subramanian, Sylvia E, Rosas, John R, Sedor, Miguel A, Vasquez, Sushrut S, Waikar, Markus, Bitzer, Subramaniam, Pennathur, Frank C, Brosius, Ian, De Boer, Min, Chen, Matthias, Kretzler, Wenjun, Ju, Kalyani, Perumal
Publikováno v:
Diabetes. 71:2664-2676
Diabetic kidney disease (DKD) is the leading cause of end-stage kidney disease (ESKD). Prognostic biomarkers reflective of underlying molecular mechanisms are critically needed for effective management of DKD. A three-marker panel was derived from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7841f9d9796e4e43ed1c57e8210f76c
https://doi.org/10.2337/db22-0169
https://doi.org/10.2337/db22-0169