Výsledky vyhledávání - "Dong-xue Zhang"

Akademický článek

NLRP3–GABA signaling pathway contributes to the pathogenesis of impulsive-like behaviors and cognitive deficits in aged mice

Autor: Lu-Ying Wang, Xu-Peng Wang, Jin-Meng Lv, Yu-Dong Shan, Shi-Yan Jia, Zhi-Fang Yu, Hui-Tao Miao, Yue Xin, Dong-Xue Zhang, Li-Min Zhang

Publikováno v: Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-15 (2023)

Abstract Background Perioperative neurocognitive disorders (PND), such as delirium and cognitive impairment, are commonly encountered complications in aged patients. The inhibitory neurotransmitter γ-aminobutyric acid (GABA) is aberrantly synthesize

Externí odkaz: https://doaj.org/article/d2d888d2ca6949cea214a6fb24a7803a

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Subanesthetic dose of S-ketamine improved cognitive dysfunction via the inhibition of hippocampal astrocytosis in a mouse model of post-stroke chronic stress

Autor: Li-Min Zhang, Zhi-You Wu, Ji-Zhen Liu, Yan Li, Jin-Meng Lv, Lu-Ying Wang, Yu-Dong Shan, Rong-Xin Song, Hui-Tao Miao, Wei Zhang, Dong-Xue Zhang

Publikováno v: Journal of Psychiatric Research. 158:1-14

Post-stroke chronic stress (PSCS) is generally associated with the poorer recovery and more pronounced cognitive dysfunction. Recent evidence has implied that S-ketamine can reduce suicidal ideation in treatment-resistant depression. In this current

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fd32f5f26260b94a5aed05af71f7fc
https://doi.org/10.1016/j.jpsychires.2022.12.010

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IL-18BP Alleviates Anxiety-Like Behavior Induced by Traumatic Stress via Inhibition of the IL-18R-NLRP3 Signaling Pathway in a Mouse Model of Hemorrhagic Shock and Resuscitation

Autor: Li-Min Zhang, Dong-Xue Zhang, Rong-Xin Song, Jin-Meng Lv, Lu-Ying Wang, Zhi-You Wu, Hui-Tao Miao, Yan-Bo Zhou, Wei Zhang, Yue Xin, Yan Li

Publikováno v: Molecular Neurobiology. 60:382-394

Psychological distress and posttraumatic stress, including anxiety, severely influence life quality. Previously, we reported that interleukin-18 (IL-18) was involved in pyroptosis-induced emotional changes in a rodent model of hemorrhagic shock and r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::561402b15e218e84e7e747f083a6663d
https://doi.org/10.1007/s12035-022-03085-x

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STING mediates neuroinflammatory response by activating NLRP3-related pyroptosis in severe traumatic brain injury

Autor: Li‐Min Zhang, Yue Xin, Zhi‐You Wu, Rong‐Xin Song, Hui‐Tao Miao, Wei‐Chao Zheng, Yan Li, Dong‐Xue Zhang, Xiao‐Chun Zhao

Publikováno v: Journal of neurochemistryREFERENCES. 162(5)

Long-term neurological deficits after severe traumatic brain injury (TBI), including cognitive dysfunction and emotional impairments, can significantly impair rehabilitation. Glial activation induced by inflammatory response is involved in the neurol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde4ef54bf08907355d9cfeb8665f75f
https://pubmed.ncbi.nlm.nih.gov/35892155

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S-ketamine administration in pregnant mice induces ADHD- and depression-like behaviors in offspring mice

Autor: Li-Min Zhang, Na-Na Liu, Lu Cao, Yue Xin, Dong-Xue Zhang, Yang Bai, Wei-Chao Zheng, Xin-Ying Bi, Bao-Heng Xing, Wei Zhang

Publikováno v: Behavioural brain research. 433

Anesthesia and psychotropic drugs in pregnant women may cause long-term effects on the brain development of unborn babies. The authors set out to investigate the neurotoxicity of S-ketamine, which possesses anesthetic and antidepressant effects and m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d4a9c5e73af32f229d355923e64dc6
https://pubmed.ncbi.nlm.nih.gov/35817136

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