Zobrazeno 1 - 10
of 717
pro vyhledávání: '"Dong-qing Wei"'
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Identification of interactions between chemical compounds and proteins is crucial for various applications, including drug discovery, target identification, network pharmacology, and elucidation of protein functions. Deep neural network-base
Externí odkaz:
https://doaj.org/article/dc654e51e3e14b6893e5e697fb4fdfbe
Autor:
Muhammad Suleman, Abduh Murshed, Kashif Imran, Abbas Khan, Zafar Ali, Norah A. Albekairi, Dong-Qing Wei, Hadi M. Yassine, Sergio Crovella
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-13 (2024)
Abstract The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has led to over six million deaths worldwide. In human immune system, the type 1 interferon (IFN) pathway plays a crucial role in fighting viral infections. However, the ORF8 protein of
Externí odkaz:
https://doaj.org/article/d7b019d7d78f4ee49ec445d873693c47
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102208- (2024)
Externí odkaz:
https://doaj.org/article/4cec6c427c5b4cd38bb92165a6e43cef
Autor:
Bowen Zhao, Jing Zhao, Muyao Wang, Yangfan Guo, Aamir Mehmood, Weibin Wang, Yi Xiong, Shenggan Luo, Dong-Qing Wei, Xin-Qing Zhao, Yanjing Wang
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Microproteins, prevalent across all kingdoms of life, play a crucial role in cell physiology and human health. Although global gene transcription is widely explored and abundantly available, our understanding of microprotein functions using
Externí odkaz:
https://doaj.org/article/061121b7779342ac896cee2e9ac9491f
Autor:
Muhammad Suleman, Muhammad Tahir ul Qamar, Kiran, Samreen Rasool, Aneela Rasool, Aqel Albutti, Noorah Alsowayeh, Ameen S. S. Alwashmi, Mohammad Abdullah Aljasir, Sajjad Ahmad, Zahid Hussain, Muhammad Rizwan, Syed Shujait Ali, Abbas Khan, Dong-Qing Wei
Publikováno v:
Vaccines, Vol 12, Iss 8, p 920 (2024)
The authors would like to make the following correction to this published paper [...]
Externí odkaz:
https://doaj.org/article/fb07759bf59c444198b97816e916987e
Autor:
Chen Zhang, Junhui Gao, Hong-Yu Chen, Lingxin Kong, Guangshuo Cao, Xiangyu Guo, Wei Liu, Bin Ren, Dong-Qing Wei
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 2, p e1011935 (2024)
Spatial transcriptomic (ST) clustering employs spatial and transcription information to group spots spatially coherent and transcriptionally similar together into the same spatial domain. Graph convolution network (GCN) and graph attention network (G
Externí odkaz:
https://doaj.org/article/d2fb7af679884f70ba285b525d58f980
Autor:
Nimra Aftab, Fahad Masood, Sajjad Ahmad, Saqib Shahid Rahim, Samira Sanami, Bilal Shaker, Dong-Qing Wei
Publikováno v:
Informatics in Medicine Unlocked, Vol 48, Iss , Pp 101526- (2024)
Blood-brain barrier (BBB) permeability prediction plays a pivotal role in drug discovery for neurological disorders which is essential for the development of central nervous system (CNS) drugs. Compounds having high permeability must be found to synt
Externí odkaz:
https://doaj.org/article/cf237b7ff74c446c8b8b0a2a01e7009c
Autor:
Muhammad Suleman, Tanveer Ahmad, Khadim shah, Norah A. Albekairi, Abdulrahman Alshammari, Abbas Khan, Dong-Qing Wei, Hadi M. Yassine, Sergio Crovella
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Amid the ongoing monkeypox outbreak, there is an urgent need for the rapid development of effective therapeutic interventions capable of countering the immune evasion mechanisms employed by the monkeypox virus (MPXV). The evasion strategy involves th
Externí odkaz:
https://doaj.org/article/9fc2a6ea185e47b5b825b7c3ef46099a
Autor:
Abbas Khan, Ayesha Liaqat, Adan Masood, Syed Shujait Ali, Liaqat Ali, Abdulrahman Alshammari, Abdullah F. Alasmari, Anwar Mohammad, Yasir Waheed, Dong-Qing Wei
Publikováno v:
Saudi Pharmaceutical Journal, Vol 31, Iss 10, Pp 101775- (2023)
The growing concerns and cases of COVID-19 with the appearance of novel variants i.e., BA.2.75. BA.5 and XBB have prompted demand for more effective treatment options that could overcome the risk of immune evasion. For this purpose, discovering novel
Externí odkaz:
https://doaj.org/article/01d3c8e28e284ba59606e320ea432219
Publikováno v:
Journal of Cheminformatics, Vol 14, Iss 1, Pp 1-12 (2022)
Abstract The joint use of multiple drugs may cause unintended drug-drug interactions (DDIs) and result in adverse consequence to the patients. Accurate identification of DDI types can not only provide hints to avoid these accidental events, but also
Externí odkaz:
https://doaj.org/article/b265213e1052499b8dafb2cd8dd01650