Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Dong-ik Lee"'
Autor:
Sean A. Murphy, Matthew Miyamoto, Anaïs Kervadec, Suraj Kannan, Emmanouil Tampakakis, Sandeep Kambhampati, Brian Leei Lin, Sam Paek, Peter Andersen, Dong-Ik Lee, Renjun Zhu, Steven S. An, David A. Kass, Hideki Uosaki, Alexandre R. Colas, Chulan Kwon
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Cardiomyocyte maturation and the acquisition of phenotypes is poorly understood at the single cell level. Here, the authors analyse the transcriptome of single cells from neonatal to adult heart and reveal that peroxisome proliferator-activated recep
Externí odkaz:
https://doaj.org/article/e529861439104233888f042c1cc8bff3
Autor:
Lincoln T Shenje, Peter Andersen, Hideki Uosaki, Laviel Fernandez, Peter P Rainer, Gun-sik Cho, Dong-ik Lee, Weimin Zhong, Richard P Harvey, David A Kass, Chulan Kwon
Publikováno v:
eLife, Vol 3 (2014)
Cardiac progenitor cells (CPCs) must control their number and fate to sustain the rapid heart growth during development, yet the intrinsic factors and environment governing these processes remain unclear. Here, we show that deletion of the ancient ce
Externí odkaz:
https://doaj.org/article/28fce4bb0d45423fb9e788b539632d97
Publikováno v:
Applied Sciences, Vol 12, Iss 15, p 7418 (2022)
Polyurethane composite foams were prepared by adding three different types of silica materials as a filler to improve the mechanical and thermal insulation properties. The first type of filler consists of silica aerogels with high-volume pores, with
Externí odkaz:
https://doaj.org/article/e604f25e93a549888f19bf7296e0124d
Autor:
Hideyuki Sasaki, Robert M. Blanton, Kazutaka Ueda, Richard H. Karas, Dong Ik Lee, Nazareno Paolocci, Brian O'Rourke, Michael E. Mendelsohn, Masaki Hashimoto, David A. Kass, Guangshuo Zhu, Yuan Yuan, Masayuki Sasaki, Eiki Takimoto, Djahida Bedja, Taro Kariya, Manling Zhang, Matthew Gabrielson, Nina Kaludercic
Publikováno v:
FEBS Lett
Phosphodiesterase 5 inhibition (PDE5i) activates cGMP-dependent protein kinase (PKG) and ameliorates heart failure; however, its impact on cardiac mitochondrial regulation has not been fully determined. Here, we investigated the role of the mitochond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca2e5243ebd6fb35e736a6cfc5be429
https://doi.org/10.1002/1873-3468.14228
https://doi.org/10.1002/1873-3468.14228
Autor:
Renjun Zhu, Dong Ik Lee, Suraj Kannan, Hideki Uosaki, Steven S. An, Sean Murphy, Sam Paek, Emmanouil Tampakakis, Sandeep Kambhampati, David A. Kass, Alexandre R. Colas, Brian L. Lin, Matthew Miyamoto, Anaïs Kervadec, Chulan Kwon, Peter Andersen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
Cardiomyocytes undergo significant structural and functional changes after birth, and these fundamental processes are essential for the heart to pump blood to the growing body. However, due to the challenges of isolating single postnatal/adult myocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0b4417c51fc055c6538ed73497a81a
https://doaj.org/article/e529861439104233888f042c1cc8bff3
https://doaj.org/article/e529861439104233888f042c1cc8bff3
Autor:
Masayuki Sasaki, Christian U. Oeing, Dong Ik Lee, Djahida Bedja, Mark J. Ranek, Taishi Nakamura, Jonathan D. Powell, Jennifer E. Van Eyk, Chirag H. Patel, Anna Chen, Miguel Pinilla Vera, Ronald J. Holewinski, Kristen M. Kokkonen-Simon, Guangshuo Zhu, David A. Kass, Brittany Dunkerly-Eyring
Publikováno v:
Nature
The mechanistic target of rapamycin complex-1 (mTORC1) coordinates regulation of growth, metabolism, protein synthesis and autophagy1. Its hyperactivation contributes to disease in numerous organs, including the heart1,2, although broad inhibition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963ccf5739aaa5a72e9b1e7524e814d8
https://doi.org/10.1038/s41586-019-0895-y
https://doi.org/10.1038/s41586-019-0895-y
Autor:
Soohwan Oh, Hye Yeon Shin, Bomi Ahn, Ji-Young Lee, Yun Sik Seo, Dong Ik Lee, Byoung-Uk Kim, Ji-Hae Kim, Jung Yoon Cha, Yoo-Sook Joung, Jeong-Yi Kwon
Publikováno v:
BMC Pediatrics
BMC Pediatrics, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Pediatrics, Vol 21, Iss 1, Pp 1-9 (2021)
Background Attention problems and decreased quality of life are frequently accompanied in Cerebral Palsy (CP), which can negatively affect rehabilitation of physical disability. However, the majority of affected children remain untreated in the aspec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3009d9cc4d44b17c4c3cd602ce93b8b7
https://pubmed.ncbi.nlm.nih.gov/33740922
https://pubmed.ncbi.nlm.nih.gov/33740922
Autor:
Djahida Bedja, Taishi Nakamura, Dong Ik Lee, Mark J. Ranek, Brian L. Lin, Brittany Dunkerly-Eyring, Guangshuo Zhu, Kristen M. Kokkonen-Simon, Christian U. Oeing, Shi Pan, David A. Kass, Anna Chen, Sumita Mishra
Publikováno v:
Circ Res
Rationale: Stimulated PKG1α (protein kinase G-1α) phosphorylates TSC2 (tuberous sclerosis complex 2) at serine 1365, potently suppressing mTORC1 (mechanistic [mammalian] target of rapamycin complex 1) activation by neurohormonal and hemodynamic str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68348e928f0a927a2982088bab4928f4
https://pubmed.ncbi.nlm.nih.gov/32393148
https://pubmed.ncbi.nlm.nih.gov/32393148
Autor:
Sam Paek, Emmanouil Tampakakis, Renjun Zhu, Anaïs Kervadec, Chulan Kwon, David A. Kass, Sean Murphy, Brian L. Lin, Sandeep Kambhampati, Matthew Miyamoto, Suraj Kannan, Hideki Uosaki, Steven S. An, Peter Andersen, Alexandre R. Colas, Dong Ik Lee
Cardiomyocytes undergo significant levels of structural and functional changes after birth—fundamental processes essential for the heart to produce the volume and contractility to pump blood to the growing body. However, due to the challenges in is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231c5b6539f836a543e61227f5eadf99
Autor:
Dong Ik Lee
Publikováno v:
Journal of Contemporary Society and Safety Culture. 1:52-68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcb115f1b858fcadf0471717349220f3
https://doi.org/10.33090/ksci.1.2.4
https://doi.org/10.33090/ksci.1.2.4