Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Dong-Yan Tsai"'
Publikováno v:
Vaccines, Vol 11, Iss 4, p 735 (2023)
Rapid mutations within SARS-CoV-2 are driving immune escape, highlighting the need for in-depth and routine analysis of memory B cells (MBCs) to complement the important but limited information from neutralizing antibody (nAb) studies. In this study,
Externí odkaz:
https://doaj.org/article/4c1be2019fa44063bc6fa601c49928a8
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-13 (2019)
Abstract Terminally differentiated B cell, the plasma cell, is the sole cell type capable of producing antibodies in our body. Over the past 30 years, the identification of many key molecules controlling B cell activation and differentiation has eluc
Externí odkaz:
https://doaj.org/article/a206491393354751b3064786a1f85d3b
Autor:
Ying-Hsiu Wang, Dong-Yan Tsai, Yi-An Ko, Tsan-Tzu Yang, I-Ying Lin, Kuo-Hsuan Hung, Kuo-I Lin
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Regulatory B cells (Bregs) are a B cell subset that plays a suppressive role in immune responses. The CD19+CD1dhiCD5+ Bregs that can execute regulatory functions via secreting IL-10 are defined as B10 cells. Bregs suppress autoimmune and inflammatory
Externí odkaz:
https://doaj.org/article/e8786aae2f3c4453a9c772ee49c3f335
Autor:
Jung-Lin Wu, Hsin-Yi Wu, Dong-Yan Tsai, Ming-Feng Chiang, Yi-Ju Chen, Shijay Gao, Chun-Cheng Lin, Chun-Hung Lin, Kay-Hooi Khoo, Yu-Ju Chen, Kuo-I. Lin
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
B cell receptor (BCR) activation can trigger signalling causing apoptosis in order to eliminate auto-reactive B cells. Here the authors show that the O-GlcNAcylation and phosphorylation of lymphocyte-specific protein-1 are involved in a switch that r
Externí odkaz:
https://doaj.org/article/f4ea53b30f1641559ce4aa1a196ad329
Autor:
Dong-Yan Tsai, 蔡東諺
106
MicroRNAs (miRNAs) are the classes of short endogenous small noncoding RNA molecules that play a crucial role as the key negative regulator in the post-transcriptional regulation. These molecules initiate inhibition of translation or degrada
MicroRNAs (miRNAs) are the classes of short endogenous small noncoding RNA molecules that play a crucial role as the key negative regulator in the post-transcriptional regulation. These molecules initiate inhibition of translation or degrada
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/94d326
Autor:
Dong-Yan Tsai, 蔡東諺
98
Hepatocyte nuclear factor 1 ( HNF1 ) is a group of phylogenetically related transcriptional factors that regulate the transcription of a diverse group of genes in human liver, kidney, small intestines, brain, and ovary tissue. These proteins
Hepatocyte nuclear factor 1 ( HNF1 ) is a group of phylogenetically related transcriptional factors that regulate the transcription of a diverse group of genes in human liver, kidney, small intestines, brain, and ovary tissue. These proteins
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/91503209468903399248
Publikováno v:
Journal of Biomedical Science
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-13 (2019)
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-13 (2019)
Terminally differentiated B cell, the plasma cell, is the sole cell type capable of producing antibodies in our body. Over the past 30 years, the identification of many key molecules controlling B cell activation and differentiation has elucidated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f921b681293189113649d35ae904fbf3
http://europepmc.org/articles/PMC6717636
http://europepmc.org/articles/PMC6717636
Autor:
Shii-Yi Yang, Shin-Tang Su, Yi-Kai Chiu, Kuo-I Lin, I-Ying Lin, Kuan-Hsiung Wang, Yi-Ting Hsieh, Dong-Yan Tsai
Publikováno v:
The Journal of Immunology. 193:2207-2217
Ag-primed B cells that result from an immune response can form either memory B cells or Ab-secreting plasma cells; however, the molecular machinery that controls this cellular fate is poorly understood. In this study, we show that activated B cell fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845e1a04f13d8f4b8fb208fc4b49485d
https://doi.org/10.4049/jimmunol.1400411
https://doi.org/10.4049/jimmunol.1400411
Autor:
Hsin-Yi Wu, Chun-Hung Lin, Yu-Ju Chen, Kuo-I Lin, Kay-Hooi Khoo, Ming-Feng Chiang, Dong-Yan Tsai, Chun-Cheng Lin, Shijay Gao, Yi-Ju Chen, Jung-Lin Wu
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Crosslinking of B-cell receptor (BCR) sets off an apoptosis programme, but the underlying pathways remain obscure. Here we decipher the molecular mechanisms bridging B-cell activation and apoptosis mediated by post-translational modification (PTM). W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5a561d3538ada85d29ccaae0d1a6e9
http://europepmc.org/articles/PMC4999498
http://europepmc.org/articles/PMC4999498
Autor:
Cheng-Han Chung, Kuo-I Lin, Kuo-Hsuan Hung, Tong-Cheng Wang, I-Ying Lin, Shih-Ying Wu, Shin-Tang Su, Dong-Yan Tsai, Wen-Hsiung Li, Arthur Chun-Chieh Shih
Publikováno v:
Scientific Reports
Using genome-wide approaches, we studied the microRNA (miRNA) expression profile during human plasma cell (PC) differentiation induced by stimulation of human blood B cells with T follicular helper cell–dependent signals. Combining the profiles of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf2012e9e4365ee46f9dfa6bf25224f
https://pubmed.ncbi.nlm.nih.gov/26655851
https://pubmed.ncbi.nlm.nih.gov/26655851