Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Dong-Ya Zhu"'
Autor:
Shi-Ying Cao, Di Yang, Zhen-Quan Huang, Yu-Hui Lin, Hai-Yin Wu, Lei Chang, Chun-Xia Luo, Yun Xu, Yan Liu, Dong-Ya Zhu
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Stroke usually causes prolonged or lifelong disability, owing to the permanent loss of infarcted tissue. Although a variety of stem cell transplantation has been explored to improve neuronal defect behavior by enhancing neuroplasticity, it r
Externí odkaz:
https://doaj.org/article/92f4f211d6c3472e94cd40b65b5d2cbb
Autor:
Yu-Hui Lin, Di Yang, Huan-Yu Ni, Xiu-Mei Xu, Feng Wu, Long Lin, Jie Chen, Yan-Yu Sun, Zhen-Quan Huang, Shi-Yi Li, Pei-Lin Jiang, Hai-Yin Wu, Lei Chang, Bo Hu, Chun-Xia Luo, Jin Wu, Dong-Ya Zhu
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112294- (2023)
Summary: Stroke is a leading cause of adult disability worldwide, and better drugs are needed to promote functional recovery after stroke. Growing evidence suggests the critical role of network excitability during the repair phase for stroke recovery
Externí odkaz:
https://doaj.org/article/1af3e2ee9fd64c7b8a7d822d072834ac
Autor:
Yan Luo, Hang Yang, Yan Wan, Sibo Yang, Jiehong Wu, Shengcai Chen, Yanan Li, Huijuan Jin, Quanwei He, Dong-Ya Zhu, Yifan Zhou, Bo Hu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-13 (2022)
Abstract Blood–brain barrier (BBB) dysfunction has been recognized as an early pathological feature and contributing factor in multiple sclerosis. Endothelial-to-mesenchymal transition is a process associated with endothelial dysfunction leading to
Externí odkaz:
https://doaj.org/article/4a50df7698aa4f859353fafd86097cf6
Autor:
Hai-Ying Liang, Zhi-Jin Chen, Hui Xiao, Yu-Hui Lin, Ying-Yi Hu, Lei Chang, Hai-Yin Wu, Peng Wang, Wei Lu, Dong-Ya Zhu, Chun-Xia Luo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Chronic pain usually induces anxiety. Here, the authors report that vmPFC nNOS-expressing neurons are activated by excitatory inputs from pPVT during chronic pain and subsequently induce anxiety-like behaviors in mice through promoting AMPAR traffick
Externí odkaz:
https://doaj.org/article/8f56e6d3aab84052a130814cd8153048
Publikováno v:
IBRO Reports, Vol 5, Iss , Pp 116-132 (2018)
Affective disorders including major depressive disorder (MDD), bipolar disorder (BPD), and general anxiety affect more than 10% of population in the world. Notably, neuronal nitric oxide synthase (nNOS), a downstream signal molecule of N-methyl-D-asp
Externí odkaz:
https://doaj.org/article/7f1f9f796a354b21a0dd478f97b7513c
Autor:
Qi-Gang Zhou, Meng-Ying Liu, Han-Woong Lee, Fuyuki Ishikawa, Sushil Devkota, Xin-Ru Shen, Xin Jin, Hai-Yin Wu, Zhigang Liu, Xiao Liu, Xun Jin, Hai-Hui Zhou, Eun Jeoung Ro, Jing Zhang, Yu Zhang, Yu-Hui Lin, Hoonkyo Suh, Dong-Ya Zhu
Publikováno v:
Stem Cell Reports, Vol 9, Iss 2, Pp 543-556 (2017)
Summary: The molecular mechanism of memory formation remains a mystery. Here, we show that TERT, the catalytic subunit of telomerase, gene knockout (Tert−/−) causes extremely poor ability in spatial memory formation. Knockdown of TERT in the dent
Externí odkaz:
https://doaj.org/article/c0c9bcb43b7444c38e4a28df9e4787e2
Autor:
Ying Tang, Yu‐Hui Lin, Huan‐Yu Ni, Jian Dong, Hong‐Jin Yuan, Yu Zhang, Hai‐Ying Liang, Meng‐Cheng Yao, Qi‐Gang Zhou, Hai‐Yin Wu, Lei Chang, Chun‐Xia Luo, Dong‐Ya Zhu
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 10 (2017)
BackgroundStroke is a leading cause of long‐term disability worldwide. However, current therapies that promote functional recovery from stroke are limited to physical rehabilitation. No pharmacological therapy is available. Thus, understanding the
Externí odkaz:
https://doaj.org/article/e016ee3809f6489e904c36d7d70a0cb1
Autor:
Li-Juan Zhu, Meng-Ying Liu, Huan Li, Xiao Liu, Chen Chen, Zhou Han, Hai-Yin Wu, Xing Jing, Hai-Hui Zhou, Hoonkyo Suh, Dong-Ya Zhu, Qi-Gang Zhou
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97689 (2014)
Hypothalamus-pituitary-adrenal (HPA) hyperactivity is observed in many patients suffering from depression and the mechanism underling the dysfunction of HPA axis is not well understood. Chronic stress has a causal relationship with the hyperactivity
Externí odkaz:
https://doaj.org/article/0372e1759d094cc099b383fa0a944c46
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 2, Pp o244-o244 (2009)
The asymmetric unit of the title compound, C16H10O8·2H2O, contains one-half of the centrosymmetric organic molecule and one water molecule. The dihedral angles between the carboxylate groups and the adjacent phenyl ring are 71.31 (3) and 16.67 (3)°
Externí odkaz:
https://doaj.org/article/ecdc3afa9e5344378493e11d8146dd71
Autor:
Cheng-Yun Cai, Yan Tao, Ying Zhou, Di Yang, Cheng Qin, Xin-Lan Bian, Jia-Yun Xian, Bo Cao, Lei Chang, Hai-Yin Wu, Chun-Xia Luo, Dong-Ya Zhu
Publikováno v:
Journal of Affective Disorders. 333:181-192
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fc4409260bf913a5f68dca5ea6e5a2a
https://doi.org/10.1016/j.jad.2023.04.049
https://doi.org/10.1016/j.jad.2023.04.049