Gut microbiota controls the development of chronic pancreatitis: A critical role of short-chain fatty acids-producing Gram-positive bacteria

Autor: Li-Long Pan, Zheng-Nan Ren, Jun Yang, Bin-Bin Li, Yi-Wen Huang, Dong-Xiao Song, Xuan Li, Jia-Jia Xu, Madhav Bhatia, Duo-Wu Zou, Chun-Hua Zhou, Jia Sun

Publikováno v: Acta Pharmaceutica Sinica B, Vol 13, Iss 10, Pp 4202-4216 (2023)

Chronic pancreatitis (CP) is a progressive and irreversible fibroinflammatory disorder, accompanied by pancreatic exocrine insufficiency and dysregulated gut microbiota. Recently, accumulating evidence has supported a correlation between gut dysbiosi

Externí odkaz: https://doaj.org/article/7efe2393fcc446ba994388aca2ac8442

Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

Autor: Ollila, Hanna M., Sharon, Eilon, Lin, Ling, Sinnott-Armstrong, Nasa, Ambati, Aditya, Yogeshwar, Selina M., Hillary, Ryan P., Jolanki, Otto, Faraco, Juliette, Einen, Mali, Luo, Guo, Zhang, Jing, Han, Fang, Yan, Han, Dong, Xiao Song, Li, Jing, Zhang, Jun, Hong, Seung Chul, Kim, Tae Won, Dauvilliers, Yves, Barateau, Lucie, Lammers, Gert Jan, Fronczek, Rolf, Mayer, Geert, Santamaria, Joan, Arnulf, Isabelle, Knudsen-Heier, Stine, Bredahl, May Kristin Lyamouri, Thorsby, Per Medbøe, Plazzi, Giuseppe, Pizza, Fabio, Moresco, Monica, Crowe, Catherine, Van den Eeden, Stephen K., Lecendreux, Michel, Bourgin, Patrice, Kanbayashi, Takashi, Martínez-Orozco, Francisco J., Peraita-Adrados, Rosa, Benetó, Antonio, Montplaisir, Jacques, Desautels, Alex, Huang, Yu Shu

Publikováno v: Ollila, H M, Sharon, E, Lin, L, Sinnott-Armstrong, N, Ambati, A, Yogeshwar, S M, Hillary, R P, Jolanki, O, Faraco, J, Einen, M, Luo, G, Zhang, J, Han, F, Yan, H, Dong, X S, Li, J, Zhang, J, Hong, S C, Kim, T W, Dauvilliers, Y, Barateau, L, Lammers, G J, Fronczek, R, Mayer, G, Santamaria, J, Arnulf, I, Knudsen-Heier, S, Bredahl, M K L, Thorsby, P M, Plazzi, G, Pizza, F, Moresco, M, Crowe, C, Van den Eeden, S K, Lecendreux, M, Bourgin, P, Kanbayashi, T, Martínez-Orozco, F J, Peraita-Adrados, R, Benetó, A, Montplaisir, J, Desautels, A, Huang, Y S & FinnGen 2023, ' Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy ', Nature Communications, vol. 14, no. 1, 2709 . https://doi.org/10.1038/s41467-023-36120-z

Narcolepsy type 1 (NT1) is caused by a loss of hypocretin/orexin transmission. Risk factors include pandemic 2009 H1N1 influenza A infection and immunization with Pandemrix®. Here, we dissect disease mechanisms and interactions with environmental tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::39e1eabe7d8f72d282ed43f20d5dc32e
https://pure.au.dk/portal/da/publications/narcolepsy-risk-loci-outline-role-of-t-cell-autoimmunity-and-infectious-triggers-in-narcolepsy(b7bb4c2b-0872-4f14-91c5-e8b0d1f9ee3d).html

A novel resveratrol analog upregulates sirtuin 1 and inhibits inflammatory cell infiltration in acute pancreatitis

Autor: Jia Sun, Xun Sun, Yi-Wen Huang, Zhengnan Ren, Meng-Ya Zhang, Li-Long Pan, Dong-Xiao Song, Jun Yang

Publikováno v: Acta Pharmacol Sin

Acute pancreatitis (AP), an inflammatory disorder of the pancreas, is a complicated disease without specific drug therapy. (R)-4,6-dimethoxy-3-(4-methoxy phenyl)-2,3-dihydro-1H-indanone [(R)-TML104] is a synthesized analog of the natural product resv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ed0f27cfa0272057de371eb0db2a48
https://doi.org/10.1038/s41401-021-00744-y

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Acute severe asthma with thyroid crisis and myasthenia: a case report and literature review.

Autor: Gong, Pi‐Hua¹, Dong, Xiao‐Song¹, Li, Chun¹, Bao, Jing¹, Cao, Zhao‐Long¹, Yuan, Yun², Zheng, Ya‐Li³, Gao, Zhan‐Cheng¹ zcgao@bjmu.edu.cn

Publikováno v: Clinical Respiratory Journal. Nov2017, Vol. 11 Issue 6, p671-676. 6p.