Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Dong-Soo Im"'
Autor:
Jung Hwa Lim, Hee Won Shin, Kyung-Sook Chung, Nam-Soon Kim, Ju Hee Kim, Hong-Ryul Jung, Dong-Soo Im, Cho-Rok Jung
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163710 (2016)
Here, we show that E2-EPF ubiquitin carrier protein (UCP) elongated E3-independent polyubiquitin chains on the lysine residues of von Hippel-Lindau protein (pVHL) and its own lysine residues both in vitro and in vivo. The initiation of the ubiquitin
Externí odkaz:
https://doaj.org/article/7effc4b7dccb4f3cb2e463904971335d
Autor:
Cho-Rok Jung, Dong-Soo Im, Kyung Hee Noh, Hyun Mi Kang, Dae-Yeul Yu, Dae-Soo Kim, Dae-Ghon Kim, Dongmin Park, Jung Hwa Lim, Tae Kyung Chang
Publikováno v:
Cellular and Molecular Life Sciences
Hepatitis B virus (HBV) X protein (HBx) is associated with hepatocarcinogenesis. E2-EPF ubiquitin carrier protein (UCP) catalyzes ubiquitination of itself and von Hippel–Lindau protein (pVHL) for degradation and associates with tumor growth and met
Autor:
Hyun Mi Kang, Kyung-Sook Chung, Dong-Soo Im, Kyung Hee Noh, Ho-Joon Lee, Hong Ryul Jung, Nam-Soon Kim, Jung Hwa Lim, Jea Woon Ryu, Dae-Soo Kim, Hyun-Soo Cho, Cho Rok Jung, Eun Su Kim
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
SCIENTIFIC REPORTS(7)
Scientific Reports
SCIENTIFIC REPORTS(7)
We fabricated a spheroid-forming unit (SFU) for efficient and economic production of cell spheroids. We optimized the protocol for generating large and homogenous liver cancer cell spheroids using Huh7 hepatocellular carcinoma (HCC) cells. The large
Autor:
Yoon Jung Choi, Jung Hwa Lim, Dae-Ghon Kim, Koo Jeong Kang, Cho-Rok Jung, Dong-Soo Im, Seung-Moo Noh
Publikováno v:
Journal of Clinical Investigation. 120:4493-4506
The human E3 ubiquitin ligase murine double minute 2 (MDM2) targets the tumor suppressor p53 for ubiquitination and degradation but also promotes its own ubiquitination and subsequent degradation. As the balance between MDM2 and p53 levels plays a cr
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1780:1062-1069
Protein arginine methyltransferase 3 (PRMT3) comprises a region not required for catalytic activity in its amino-terminus and the core domain catalyzing protein arginine methylation. PRMT3 has been shown to interact with the 40S ribosomal protein S2
Autor:
Cho Rok Jung, Jinsang Yoo, Kyung Sun Hwang, Dong Soo Im, Woo Ho Kim, Won-Kyung Cho, Jin Man Kim
Publikováno v:
Nature Medicine. 12:809-816
The von Hippel-Lindau tumor suppressor, pVHL, forms part of an E3 ubiquitin ligase complex that targets specific substrates for degradation, including hypoxia-inducible factor-1alpha (HIF-1alpha), which is involved in tumor progression and angiogenes
Publikováno v:
Virology. 313(2):364-376
Interaction between the adenoassociated virus (AAV) replication proteins, Rep68 and 78, and the viral terminal repeats (TRs) is mediated by a DNA sequence termed the Rep-binding element (RBE). This element is necessary for Rep-mediated unwinding of d
Publikováno v:
Vaccine. 19:2955-2964
The E1 and E2 proteins of hepatitis C virus (HCV) are believed to be the viral envelope glycoproteins that are major candidate antigens for HCV vaccine development. We reported previously that the replication-competent recombinant adenovirus encoding
Publikováno v:
Journal of Biological Chemistry. 276:11393-11401
We found that JBP1, known as a human homolog (Skb1Hs) of Skb1 of fission yeast, interacts with NS3 of the hepatitis C virus in a yeast two-hybrid screen. Amino acid sequence analysis revealed that Skb1Hs/JBP1 contains conserved motifs ofS-adenosyl-l-
Publikováno v:
Journal of Virological Methods. 59:13-21
A full-length and a truncated gene for the core protein of hepatitis C virus (HCV) were linked to the gene for glutathione S-transferase (GST), and the expression of each GST-HCV core fusion protein was analyzed. The truncated GST-HCV core (1-123) fu