Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Dong-Seok Cha"'
Publikováno v:
Applied Sciences, Vol 11, Iss 19, p 9125 (2021)
A concise synthesis of the proposed structure of aaptoline B, a pyrroloquinoline derived from a marine sponge, was accomplished. A key feature of this synthesis is the versatile transition metal-catalyzed cycloisomerization of N-propargylaniline to c
Externí odkaz:
https://doaj.org/article/c157efc170444c20b431da3ef66fbb9a
Publikováno v:
Molecules, Vol 29, Iss 19, p 4531 (2024)
Alcohol use disorder (AUD) is the most common substance use disorder and poses a significant global health challenge. Despite pharmacological advances, no single drug effectively treats all AUD patients. This study explores the protective potential o
Externí odkaz:
https://doaj.org/article/cb17a6939530400f99062eb1d213aef4
Publikováno v:
Journal of HerbMed Pharmacology, Vol 12, Iss 3, Pp 356-361 (2023)
Introduction: As a traditional medicine, the aerial parts of Leonurus japonicus Houtt. (Lamiaceae), aka motherwort, have been extensively used to treat gynecological diseases. The current study was designed to investigate the longevity properties of
Externí odkaz:
https://doaj.org/article/4c7f3d7f6833471da1c5df85fcdf865f
Publikováno v:
Pharmaceutical Biology, Vol 55, Iss 1, Pp 481-486 (2017)
Context: The twigs of Sorbus alnifolia (Sieb. et Zucc.) K. Koch (Rosaceae) have been used to treat neurological disorders as a traditional medicine in Korea. However, there are limited data describing the efficacy of S. alnifolia in Parkinson’s dis
Externí odkaz:
https://doaj.org/article/4adba2bc014142c594505f3a56c1e7fb
Publikováno v:
Journal of HerbMed Pharmacology, Vol 10, Iss 2, Pp 226-231 (2021)
Introduction: Previous studies have suggested that high glucose (HG) condition shortens the lifespan of worms by increasing glycolytic flux followed by accelerating reactive oxygen species (ROS) production, termed glucose toxicity. This study was des
Publikováno v:
Applied Sciences, Vol 9, Iss 19, p 4014 (2019)
Plant-derived antioxidants have been widely used as supplementary health foods, as well as having been regarded as drug candidates for aging and aging-associated diseases. Oleracones, a novel series of flavonoids isolated from Portulaca oleracea L.,
Externí odkaz:
https://doaj.org/article/6a330adfa92c4ec6b44331435d3330db
Publikováno v:
Chemistrybiodiversity. 19(5)
Evodileptin B (1) is a natural anthranilate derivative isolated from the ethanol extract of the aerial parts of Evodia lepta (Spreng.) Merr., a traditional medicinal plant of the family Rutaceae. We readily synthesized 1 via the amidation of phloreti
Publikováno v:
Molecules
Volume 26
Issue 19
Molecules, Vol 26, Iss 5964, p 5964 (2021)
Volume 26
Issue 19
Molecules, Vol 26, Iss 5964, p 5964 (2021)
A concise and efficient synthesis of the proposed structure of aaptoline A, a 7,8-dihydroxyquinoline derived from a marine sponge, was accomplished in seven steps with a 52% overall yield. A key feature of the synthesis is the high-yielding Ag(I)-cat
Publikováno v:
Neuroscience letters. 747
In this study, we evaluated the protective effects of damaurone D (DaD), a dihydropyranoaurone compound, on dopaminergic (DA) neurodegeneration in Caenorhabditis elegans. The results showed that DaD treatment could successfully increase the survival
Publikováno v:
BioFactors (Oxford, England)REFERENCES. 46(6)
In this study, we investigated the longevity effects of hispidol, a 6,4'-dihydroxyaurone, using the Caenorhabditis elegans model system. Our lifespan assay data revealed that hispidol could prolong the lifespan of wild-type worms under normal culture