Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Dong-Hyun Yun"'
Autor:
Anna Bianchi-Smiraglia, David W. Wolff, Daniel J. Marston, Zhiyong Deng, Zhannan Han, Sudha Moparthy, Rebecca M. Wombacher, Ashley L. Mussell, Shichen Shen, Jialin Chen, Dong-Hyun Yun, Anderson O’Brien Cox, Cristina M. Furdui, Edward Hurley, Maria Laura Feltri, Jun Qu, Thomas Hollis, Jules Berlin Nde Kengne, Bernard Fongang, Rui J. Sousa, Mikhail E. Kandel, Eugene S. Kandel, Klaus M. Hahn, Mikhail A. Nikiforov
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Changes in intracellular GTP levels are not considered as a regulatory event in RAC1 activation in live cells since total GTP levels are substantially higher than the RAC1 GTP dissociation constant determined in vitro. Here, the authors demonstrate t
Externí odkaz:
https://doaj.org/article/8aee079d643942f4a47c971818bffc85
Autor:
Anna Bianchi-Smiraglia, David W. Wolff, Daniel J. Marston, Zhiyong Deng, Zhannan Han, Sudha Moparthy, Rebecca M. Wombacher, Ashley L. Mussell, Shichen Shen, Jialin Chen, Dong-Hyun Yun, Anderson O’Brien Cox, Cristina M. Furdui, Edward Hurley, Maria Laura Feltri, Jun Qu, Thomas Hollis, Jules Berlin Nde Kengne, Bernard Fongang, Rui J. Sousa, Mikhail E. Kandel, Eugene S. Kandel, Klaus M. Hahn, Mikhail A. Nikiforov
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/09f7fc50b96d4098b94d7fd143a62297
Autor:
Thomas Hollis, Maria Laura Feltri, Anderson O’Brien Cox, Jun Qu, Jules Berlin Nde Kengne, Zhiyong Deng, Jialin Chen, Rebecca M. Wombacher, Anna Bianchi-Smiraglia, Mikhail E. Kandel, Klaus M. Hahn, Shichen Shen, Sudha Moparthy, David W. Wolff, Bernard Fongang, Ashley L. Mussell, Eugene S. Kandel, Cristina M. Furdui, Rui J Sousa, Mikhail A. Nikiforov, Daniel J. Marston, Zhannan Han, Dong Hyun Yun, Edward Hurley
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Autor:
Klaus M. Hahn, Shichen Shen, Jules Berlin Nde Kengne, Rebecca M. Wombacher, Anna Bianchi-Smiraglia, Mikhail A. Nikiforov, Jun Qu, Zhiyong Deng, Daniel J. Marston, Eugene S. Kandel, Zhannan Han, Cristina M. Furdui, Bernard Fongang, Dong Hyun Yun, Mikhail E. Kandel, Edward Hurley, Maria Laura Feltri, Anderson O’Brien Cox, Ashley L. Mussell, Jialin Chen, Thomas Hollis, Sudha Moparthy, David W. Wolff, Rui J Sousa
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Physiological changes in GTP levels in live cells have never been considered a regulatory step of RAC1 activation because intracellular GTP concentration (determined by chromatography or mass spectrometry) was shown to be substantially higher than th
Autor:
David W. Wolff, Zhiyong Deng, Anna Bianchi-Smiraglia, Colleen E. Foley, Zhannan Han, Xingyou Wang, Shichen Shen, Masha M. Rosenberg, Sudha Moparthy, Dong Hyun Yun, Jialin Chen, Brian K. Baker, Matthew V. Roll, Andrew J. Magiera, Jun Li, Edward Hurley, Maria Laura Feltri, Anderson O. Cox, Jingyun Lee, Cristina M. Furdui, Liang Liu, Wiam Bshara, Leslie E.W. LaConte, Eugene S. Kandel, Elena B. Pasquale, Jun Qu, Lizbeth Hedstrom, Mikhail A. Nikiforov
Publikováno v:
Cell Chem Biol
Signal transduction pathways post-translationally regulating nucleotide metabolism remain largely unknown. Guanosine monophosphate reductase (GMPR) is a nucleotide metabolism enzyme that decreases GTP pools by converting GMP to IMP. We observed that
Autor:
Anna Bianchi-Smiraglia, Emily E. Fink, Zhannan Han, Sudha Moparthy, Jingyun Lee, Mikhail A. Nikiforov, Adam Utley, David W. Wolff, Cristina M. Furdui, Liang Liu, Brittany C. Lipchick, Kelvin P. Lee, Dong Hyun Yun
Publikováno v:
Blood Adv
Resistance to the proteasome inhibitor bortezomib (BTZ) represents a major obstacle in the treatment of multiple myeloma (MM). The contribution of lipid metabolism in the resistance of MM cells to BTZ is mostly unknown. Here we report that levels of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6519c26a49cbfd2bbc4c6c8f2edb86
https://europepmc.org/articles/PMC8045499/
https://europepmc.org/articles/PMC8045499/
Autor:
Peter Jowdy, Sofia G. Georgieva, Song Liu, Masha Kolesnikova, Leslie M. Paul, Kalyana Moparthy, Shaila Mudambi, A. E. Berman, Eugene S. Kandel, Emily E. Fink, György Paragh, Anthony Polechetti, Brian Wrazen, Archis Bagati, Jianmin Wang, Dong Hyun Yun, Matthew V. Roll, Kateryna Kolesnikova, Galina E. Morozevich, Mikhail A. Nikiforov, David W. Wolff, Neil F. Box, Sudha Moparthy, Anna Bianchi-Smiraglia, Brittany C. Lipchick, Gal Shafirstein
Publikováno v:
Cell Death & Differentiation. 25:1040-1049
Oncogenic transcription factor FOXQ1 has been implicated in promotion of multiple transformed phenotypes in carcinoma cells. Recently, we have characterized FOXQ1 as a melanoma tumor suppressor that acts via repression of N-cadherin gene, and invasio
Autor:
A. E. Berman, Amin Mahpour, Sudha Moparthy, Joseph A. Wawrzyniak, Kateryna Kolesnikova, Jianmin Wang, Nadezhda I. Kozlova, Anthony Polechetti, Michael J. Nemeth, Dong Hyun Yun, Jason Ross, Peter Jowdy, Song Liu, Anna Bianchi-Smiraglia, Masha Kolesnikova, György Paragh, Brittany C. Lipchick, Mikhail A. Nikiforov, Archis Bagati, Emily E. Fink
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2820-2832 (2017)
Opposite lineage-specific regulation of tumor progression by the same transcription factor is an understudied phenomenon. Here, we report that levels of a carcinoma oncogenic transcription factor FOXQ1 are decreased during melanoma progression. Moreo
Autor:
Cesar Rodriguez, David W. Wolff, Wiam Bshara, Eugene S. Kandel, A. E. Berman, Nadezhda I. Kozlova, Zhannan Han, Anna Bianchi-Smiraglia, Brittany C. Lipchick, Sudha Moparthy, Peter Jowdy, Emily E. Fink, Matthew V. Roll, Archis Bagati, Dong Hyun Yun, Maria S. Soengas, Mikhail A. Nikiforov, Olga Udartseva, György Paragh, Neil F. Box, Masha Kolesnikova
Although antioxidants promote melanoma metastasis, the role of reactive oxygen species (ROS) in other stages of melanoma progression is controversial. Moreover, genes regulating ROS have not been functionally characterized throughout the entire tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0786ca3d432b78462458d82736c4e12
https://europepmc.org/articles/PMC6939757/
https://europepmc.org/articles/PMC6939757/
Publikováno v:
The Transactions of The Korean Institute of Electrical Engineers. 64:1543-1550
Ferroresonance is a non-linear vibrational phenomenon that is generated by the electrical interaction of the inductance compon ent with the capacitor component of a certain capacitance as the device of the inductance component such as a transformer i