Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Dong-Hua Chen"'
Publikováno v:
Regenerative Therapy, Vol 25, Iss , Pp 377-386 (2024)
Cerebral small vessel disease (CSVD), as the most common, chronic and progressive vascular disease on the brain, is a serious neurological disease, whose pathogenesis remains unclear. The disease is a leading cause of stroke and vascular cognitive im
Externí odkaz:
https://doaj.org/article/93185f3859114e88982597a1f4dc0703
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionPatients with mitochondrial disorders always show neurological deficits. However, the diversity of clinical manifestations, genetic heterogeneity and threshold effect caused by maternal heredity make its diagnosis very challenging.Case pr
Externí odkaz:
https://doaj.org/article/c91d8458c6e5411ea3a28460ac4f89eb
Autor:
Betty Ha, Kevin P. Larsen, Jingji Zhang, Ziao Fu, Elizabeth Montabana, Lynnette N. Jackson, Dong-Hua Chen, Elisabetta Viani Puglisi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Initiation of HIV-1 reverse transcription occurs at the host tRNALys 3, which forms a complex with the 5’ end of the HIV-1 viral RNA and reverse transcriptase (RT). Here, the authors present the 2.8 Å cryo-EM structure of a minimal HIV-1 RT–vRNA
Externí odkaz:
https://doaj.org/article/428ee5420f604c7da4a4e2a37fe10591
Autor:
Stefan L. Oliver, Yi Xing, Dong-Hua Chen, Soung Hun Roh, Grigore D. Pintilie, David A. Bushnell, Marvin H. Sommer, Edward Yang, Andrea Carfi, Wah Chiu, Ann M. Arvin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Herpesvirus virions have an outer lipid membrane dotted with glycoproteins that enable fusion with cell membranes to initiate entry and establish infection. Here the authors elucidate the structural mechanism of a neutralizing antibody derived from a
Externí odkaz:
https://doaj.org/article/29372bf848da493084861c63723dc16f
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
HCMV is a herpesvirus that infects a large percentage of the adult population and causes significant levels of disease in immunocompromised individuals and birth defects in the developing fetus. The virus encodes a complex protein machinery that coor
Externí odkaz:
https://doaj.org/article/99a3ab6028954f238a25604e90e9a233
Autor:
Dong-Hua Chen, En-Hua Jiang
Publikováno v:
Entropy, Vol 24, Iss 12, p 1756 (2022)
This article investigates two-way communications between an access point (AP) and multiple terminals in low-cost Internet of Things (IoT) networks. The main issues considered are the asymmetric transmission traffic on the uplink (UL) and downlink (DL
Externí odkaz:
https://doaj.org/article/950d9194b5d54770adb3202be3e00744
Autor:
Stefan L Oliver, Yi Xing, Dong-Hua Chen, Soung Hun Roh, Grigore D Pintilie, David A Bushnell, Marvin H Sommer, Edward Yang, Andrea Carfi, Wah Chiu, Ann M Arvin
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1008961 (2021)
Varicella-zoster virus (VZV) is a medically important alphaherpesvirus that induces fusion of the virion envelope and the cell membrane during entry, and between cells to form polykaryocytes within infected tissues during pathogenesis. All members of
Externí odkaz:
https://doaj.org/article/c4890a45b6ac4eeca285c6e266444e51
Autor:
Xuan-shan Liu, Chao-chao Liang, Shu-guo Hou, Xin Wang, Dong-hua Chen, Jian-lin Shen, Wei Zhang, Mei Wang
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Guard cells shrink in response to drought stress and abscisic acid (ABA) signaling, thereby reducing stomatal aperture. Hydrogen peroxide (H2O2) is an important signaling molecule acting to induce stomatal closure. As yet, the molecular basis of cont
Externí odkaz:
https://doaj.org/article/70388c230bde459687ef96720ba71718
Autor:
Wei Kan, Michael D Enos, Elgin Korkmazhan, Stefan Muennich, Dong-Hua Chen, Melissa V Gammons, Mansi Vasishtha, Mariann Bienz, Alexander R Dunn, Georgios Skiniotis, William I Weis
Publikováno v:
eLife, Vol 9 (2020)
In Wnt/β-catenin signaling, the transcriptional coactivator β-catenin is regulated by its phosphorylation in a complex that includes the scaffold protein Axin and associated kinases. Wnt binding to its coreceptors activates the cytosolic effector D
Externí odkaz:
https://doaj.org/article/909d22a097d24da0a1d1f2431d614ce4
Autor:
Chun-Hsiung Wang, Dong-Hua Chen, Shih-Hsin Huang, Yi-Min Wu, Yi-Yun Chen, Yeukuang Hwu, David Bushnell, Roger Kornberg, Wei-Hau Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6859 (2021)
During this global pandemic, cryo-EM has made a great impact on the structure determination of COVID-19 proteins. However, nearly all high-resolution results are based on data acquired on state-of-the-art microscopes where their availability is restr
Externí odkaz:
https://doaj.org/article/1cebfcd4aacc44869e6376e72baa9ae8