Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Dong-Hou Kim"'
Autor:
Ha-Lim Song, Min-Seok Kim, Woo-Young Cho, Ye-Seul Yoo, Jae-You Kim, Tae-Wook Kim, Hyori Kim, Dong-Hou Kim, Seung-Yong Yoon
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/2c5c10c61cc04a19bbd5b890b6dc6095
Autor:
Min-Seok Kim, Kwangmin Cho, Mi-Hyang Cho, Na-Young Kim, Kyunggon Kim, Dong-Hou Kim, Seung-Yong Yoon
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Backgrounds The expression of major histocompatibility complex I (MHC-I) in neurons has recently been shown to regulate neurite outgrowth and synaptic plasticity. However, its contribution to neurodegenerative diseases such as Alzheimer's di
Externí odkaz:
https://doaj.org/article/ddc1c162557a40a6b2cd03383b471841
Autor:
Ha-Lim Song, Na-Young Kim, Jaewan Park, Meong Il Kim, Yu-Na Jeon, Se-Jong Lee, Kwangmin Cho, Young-Lim Shim, Kyoung-Hye Lee, Yeon-Seon Mun, Jung-A Song, Min-Seok Kim, Chan-Gi Pack, Minkyo Jung, Hyemin Jang, Duk L. Na, Minsun Hong, Dong-Hou Kim, Seung-Yong Yoon
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 8 (2023)
The spatiotemporal pattern of the spread of pathologically modified tau through brain regions in Alzheimer’s disease (AD) can be explained by prion-like cell-to-cell seeding and propagation of misfolded tau aggregates. Hence, to develop targeted th
Externí odkaz:
https://doaj.org/article/77c533ffd920419dbb5df9f87c1220e9
Autor:
Atanas Vladimirov Demirev, Ha-Lim Song, Mi-Hyang Cho, Kwangmin Cho, Jong-Jin Peak, Hyun Ju Yoo, Dong-Hou Kim, Seung-Yong Yoon
Publikováno v:
Neurobiology of Disease, Vol 129, Iss , Pp 182-194 (2019)
The link between Val232Met variant of phospholipase D3 (PLD3) and late-onset Alzheimer's disease (AD) is still obscure. While it may not affect directly the amyloid precursor protein function, PLD3 could be regulating multiple cellular compartments.
Externí odkaz:
https://doaj.org/article/9bf34ba05cb8455dbca17351cded7410
Autor:
Kyu-Ho Shim, Soo-Hwan Kim, Joon Hur, Dong-Hou Kim, Atanas Vladimirov Demirev, Seung-Yong Yoon
Publikováno v:
Neurobiology of Disease, Vol 130, Iss , Pp 104519- (2019)
The intraneuronal aggregates of hyperphosphorylated and misfolded tau (neurofibrillary tangles, NFTs) cause a stereotypical spatiotemporal Alzheimer's disease (AD) progression that correlates with the severity of the associated cognitive decline. Kin
Externí odkaz:
https://doaj.org/article/4b3f8c020bb24b61b7a94ca5c0fedea4
Autor:
Dong-Hou Kim, Jae-Wan Huh, Mi Jang, Jung-Hyun Suh, Tae-Wan Kim, Jeong-Su Park, Seung-Yong Yoon
Publikováno v:
Neurobiology of Disease, Vol 46, Iss 1, Pp 52-58 (2012)
Increasing evidence supports an association between Alzheimer's disease (AD) and diabetes. In this context, anti-diabetic agents such as rosiglitazone and glucagon-like peptide (GLP)-1 have been reported to reduce pathologies associated with AD, incl
Externí odkaz:
https://doaj.org/article/38f92839023e4d6b95e9edc685156b5b
Autor:
Seung-Yong Yoon, Jeong-Su Park, Jung-Eun Choi, Jin-Myung Choi, Woo-Je Lee, Seong-Who Kim, Dong-Hou Kim
Publikováno v:
Neurobiology of Disease, Vol 40, Iss 2, Pp 449-455 (2010)
Increasing evidence supports an association between Alzheimer's disease (AD) and diabetes. Rosiglitazone, a peroxisome proliferator-activated receptor-γ (PPARγ) agonist, which is an anti-diabetic agent against type 2 diabetes, is currently in Phase
Externí odkaz:
https://doaj.org/article/2ded1604178e451595b8f92c6829b038
Autor:
Min-Seok Kim, Yeon-Seon Mun, Seung-Eun Lee, Woo-Young Cho, Seung-Hwan Han, Dong-Hou Kim, Seung-Yong Yoon
Publikováno v:
The International journal of neuroscience.
Accumulation of hyperphosphorylated tau is a key pathological finding of Alzheimer's disease. Recently, acetylation of tau is emerging as another key pathogenic modification, especially regarding the acetylation of tau at K280 of the hexapeptideThe h
Autor:
Dong-Hou Kim, Ha-Lim Song, Mi-Hyang Cho, Seung-Yong Yoon, Hyun Ju Yoo, Kwangmin Cho, Atanas Vladimirov Demirev, Jong-Jin Peak
Publikováno v:
Neurobiology of Disease, Vol 129, Iss, Pp 182-194 (2019)
The link between Val232Met variant of phospholipase D3 (PLD3) and late-onset Alzheimer's disease (AD) is still obscure. While it may not affect directly the amyloid precursor protein function, PLD3 could be regulating multiple cellular compartments.
Publikováno v:
Molecular and Cellular Neuroscience. 95:13-24
The number of neurofibrillary tangles containing abnormal hyperphosphorylated tau protein correlates with the degree of dementia in Alzheimer's disease (AD). In addition, autophagosome accumulation and disturbance of autophagy, the process by which t