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pro vyhledávání: '"Dong-Hoon Yeom"'
Autor:
Dong-Hoon Yeom, Yo-Seob Lee, Ilhwan Ryu, Sunju Lee, Byungje Sung, Han-Byul Lee, Dongin Kim, Jin-Hyung Ahn, Eunsin Ha, Yong-Soo Choi, Sang Hoon Lee, Weon-Kyoo You
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 241 (2020)
Delta-like-ligand 4 (DLL4) is a promising target to augment the effects of VEGF inhibitors. A simultaneous blockade of VEGF/VEGFR and DLL4/Notch signaling pathways leads to more potent anti-cancer effects by synergistic anti-angiogenic mechanisms in
Externí odkaz:
https://doaj.org/article/e44b45248cf84ad48a50040e81407fbb
Publikováno v:
Anti-cancer drugs. 18(9)
Trichostatin A and helixor A increased thrombospondin-1 expression by ECV304 cells at both mRNA and protein levels by transcriptional activation through the enhancement of tsp-1 promoter activity. The induction of thrombospondin-1 by these agents pot
Publikováno v:
Experimentalmolecular medicine. 36(4)
Thrombospondin-1 (TSP-1) level is tightly regulated at the transcriptional level. To determine the detailed molecular mechanisms of TSP-1 expression, nine serial 5'-deletion constructs of the human genomic tsp-1 promoter (nucleotides -2,220 to +756)