Zobrazeno 1 - 10
of 283
pro vyhledávání: '"Dong-Gyu Jo"'
Autor:
You Jung Kang, Seung Jae Hyeon, Amanda McQuade, Jiwoon Lim, Seung Hyun Baek, Yen N. Diep, Khanh V. Do, Yeji Jeon, Dong‐Gyu Jo, C. Justin Lee, Mathew Blurton‐Jones, Hoon Ryu, Hansang Cho
Publikováno v:
Advanced Science, Vol 11, Iss 20, Pp n/a-n/a (2024)
Abstract Microglial neuroinflammation appears to be neuroprotective in the early pathological stage, yet neurotoxic, which often precedes neurodegeneration in Alzheimer's disease (AD). However, it remains unclear how the microglial activities transit
Externí odkaz:
https://doaj.org/article/5e189f2581fa4244ab1a0031b7cea481
Autor:
Tai Kyoung Kim, Yongeun Cho, Jaewon Kim, Jeongmi Lee, Ju-Mi Hong, Heewon Cho, Jun-Sik Kim, Yeongyeong Lee, Kyung Hee Kim, Il-Chan Kim, Se Jong Han, Hyuncheol Oh, Dong-Gyu Jo, Joung Han Yim
Publikováno v:
Molecules, Vol 29, Iss 15, p 3701 (2024)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder marked by the accumulation of amyloid-beta plaques and hyperphosphorylated tau proteins, leading to cognitive decline and neuronal death. However, despite extensive research, ther
Externí odkaz:
https://doaj.org/article/8503256eb9b944b28f049e31901f13e6
Publikováno v:
Food Science and Human Wellness, Vol 12, Iss 4, Pp 1287-1299 (2023)
Many approaches to neurodegenerative diseases that focus on amyloid-β clearance and gene therapy have not been successful. Some therapeutic applications focus on enhancing neuronal cell survival during the pathogenesis of neurodegenerative diseases,
Externí odkaz:
https://doaj.org/article/595cbb49ab3e4b289a642ebd2a69ccff
Autor:
Vismitha Rajeev, Yuek Ling Chai, Luting Poh, Sharmelee Selvaraji, David Y. Fann, Dong-Gyu Jo, T. Michael De Silva, Grant R. Drummond, Christopher G. Sobey, Thiruma V. Arumugam, Christopher P. Chen, Mitchell K. P. Lai
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-23 (2023)
Abstract Vascular cognitive impairment (VCI) describes a wide spectrum of cognitive deficits related to cerebrovascular diseases. Although the loss of blood flow to cortical regions critically involved in cognitive processes must feature as the main
Externí odkaz:
https://doaj.org/article/04bdcb4ece6c4c74836318eba6c538d7
Autor:
Thiruma V Arumugam, Asfa Alli-Shaik, Elisa A Liehn, Sharmelee Selvaraji, Luting Poh, Vismitha Rajeev, Yoonsuk Cho, Yongeun Cho, Jongho Kim, Joonki Kim, Hannah LF Swa, David Tan Zhi Hao, Chutima Rattanasopa, David Yang-Wei Fann, David Castano Mayan, Gavin Yong-Quan Ng, Sang-Ha Baik, Karthik Mallilankaraman, Mathias Gelderblom, Grant R Drummond, Christopher G Sobey, Brian K Kennedy, Roshni R Singaraja, Mark P Mattson, Dong-Gyu Jo, Jayantha Gunaratne
Publikováno v:
eLife, Vol 12 (2023)
Intermittent fasting (IF) has been shown to reduce cardiovascular risk factors in both animals and humans, and can protect the heart against ischemic injury in models of myocardial infarction. However, the underlying molecular mechanisms behind these
Externí odkaz:
https://doaj.org/article/77c3c141082e4538bda530d5762d0666
Autor:
Luting Poh, Wei Liang Sim, Dong-Gyu Jo, Quynh Nhu Dinh, Grant R. Drummond, Christopher G. Sobey, Christopher Li-Hsian Chen, Mitchell K. P. Lai, David Y. Fann, Thiruma V. Arumugam
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-28 (2022)
Abstract There is an increasing prevalence of Vascular Cognitive Impairment (VCI) worldwide, and several studies have suggested that Chronic Cerebral Hypoperfusion (CCH) plays a critical role in disease onset and progression. However, there is a limi
Externí odkaz:
https://doaj.org/article/4528faef65554757a2c20a9e14143145
Autor:
Rin Khang, Areum Jo, Hojin Kang, Hanna Kim, Eunsang Kwag, Ji-Yeong Lee, Okjae Koo, Jinsu Park, Hark Kyun Kim, Dong-Gyu Jo, Inwoo Hwang, Jee-Yin Ahn, Yunjong Lee, Jeong-Yun Choi, Yun-Song Lee, Joo-Ho Shin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Although Krüppel-associated box domain-containing zinc-finger proteins (K-ZNFs) may be associated with sophisticated gene regulation in higher organisms, the physiological functions of most K-ZNFs remain unknown. The Zfp212 protein was high
Externí odkaz:
https://doaj.org/article/d066dbca80bf45fa93f045bb7639c08f
Autor:
Ha-Na Woo, Sujeong Park, Hae Lin Kim, Min-Kyo Jung, Chan-Gi Pack, Jinsu Park, Yoonsuk Cho, Dong-Gyu Jo, Dong Kyu Kim, Inhee Mook-Jung, Seong Who Kim, Heuiran Lee
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 643-656 (2021)
Adult hippocampal neurogenesis supports the structural and functional plasticity of the brain, while its decline is associated with neurodegeneration common in Alzheimer’s disease (AD). Although the dysregulation of certain microRNAs (miRNAs) in AD
Externí odkaz:
https://doaj.org/article/e33f82b4b82d41ed8461a078255b6d00
Autor:
Sang Ah Yi, Jieun Lee, Sun Kyu Park, Jeom Yong Kim, Jong Woo Park, Min Gyu Lee, Ki Hong Nam, Jee Hun Park, Hwamok Oh, Saetbyul Kim, Jihoon Han, Bo Kyung Kim, Dong-Gyu Jo, Jeung-Whan Han
Publikováno v:
Journal of Ginseng Research, Vol 44, Iss 1, Pp 58-66 (2020)
Background: The biological and pharmacological effects of BST204, a fermented ginseng extract, have been reported in various disease conditions. However, its molecular action in metabolic disease remains poorly understood. In this study, we identifie
Externí odkaz:
https://doaj.org/article/45d4cdaeb80c4121a470736ef474c600
Autor:
Yiran Liu, David Castano, Francesco Girolamo, Laia Trigueros-Motos, Han-Gyu Bae, Suat Peng Neo, Jeongah Oh, Pradeep Narayanaswamy, Federico Torta, Kerry Anne Rye, Dong-Gyu Jo, Jayantha Gunaratne, Sangyong Jung, Daniela Virgintino, Roshni R. Singaraja
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 1, Pp 100147- (2022)
The myelin sheath, which is wrapped around axons, is a lipid-enriched structure produced by mature oligodendrocytes. Disruption of the myelin sheath is observed in several neurological diseases, such as multiple sclerosis. A crucial component of myel
Externí odkaz:
https://doaj.org/article/622ddf4efa064a70bc8d47a1a10e6767