Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Dong-Chool Kim"'
Publikováno v:
Journal of Pharmaceutical Investigation. 44:339-349
Poly(d,l-lactide-co-glycolide) nanoparticle (PLGA NP) have been broadly studied as a carrier for drug delivery system of peptides and proteins. However, negative surface charge of PLGA NP using only PLGA decreases bioavailability under oral administr
Autor:
Dong-Chool Kim, Won-Sun Oh
Publikováno v:
Management & Information Systems Review. 28:69-98
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 32:512-525
A rapid and sensitive high performance liquid chromatography (HPLC) method has been developed and validated for the quantitative determination of a new molecule, 6-methyl-3-phenethyl-3,4-dihydro-1H-quinazoline-2-thione from solid lipid nanoparticles
Publikováno v:
Drug Delivery. 16:52-56
Non-invasive transdermal delivery using microneedle arrays was recently introduced to deliver a variety of large and hydrophilic compounds into the skin, including proteins and DNA. In this study, a microneedle array was applied to the delivery of a
Publikováno v:
Journal of Korean Pharmaceutical Sciences. 37:131-135
A previous report recently demonstrated that ultrasound-induced hyperthermia (USHT:0.4 watts (W)/ at ) could increase cellular uptake of P-glycoprotein (P-gp) substrates in P-gp expressing cancer cell lines. Since P-gp plays a major role in limiting
Publikováno v:
International Journal of Pharmaceutics. 274:107-117
An orally applicable nifedipine-loaded core tablets was coated using high viscosity grade HPMC (100,000 cps) in ethanol/water cosolvent. The release of coated tablet was evaluated using USP paddle method in 900 ml of simulated gastric fluid (pH 1.2)
Autor:
Dae-Duk Kim, Dong-Chool Kim, Chong-Kook Kim, Jun-Shik Choi, Beom-Jin Lee, Jong-Dal Rhee, Chae Ha Yang, Han-Gon Choi, Chul Soon Yong
Publikováno v:
International Journal of Pharmaceutics. 269:169-176
To improve the bioavailability of poorly water-soluble ibuprofen in the rectum with poloxamer and menthol, the effects of menthol and poloxamer 188 on the aqueous solubility of ibuprofen were investigated. The dissolution and pharmacokinetic study of
Publikováno v:
Journal of Korean Pharmaceutical Sciences. 33:195-199
The objective of this study is to investigate the pharamacokinetic parameters of decursinol following oral administration in Sprague-Dawley rats. The plasma concentration of decursinol was determined by LC/MS with APCI positive mode. The m/z value of
Autor:
Dong-Chool Kim, Chong-Kook Kim, Chul Soon Yong, Han-Gon Choi, Se Hyun Jung, Young Wook Choi, Jong-Dal Rhee, Beom-Jin Lee
Publikováno v:
Drug Delivery. 10:179-183
To improve the solubility and in vitro dissolution of poorly water-soluble ibuprofen with poloxamer and menthol, the effects of menthol and poloxamer 188 on the aqueous solubility of ibuprofen were investigated. The dissolution study of ibuprofen del
Publikováno v:
Journal of Magnetism and Magnetic Materials. 163:373-377
The intrinsic magnetic properties of Sm 2 Fe 17 N 2.8 were investigated by high-field vibrating-sample magnetometer measurements and by calculation in the temperature range 4.2–290 K. From the results, it was found that K 2 is larger than K 1 below