Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dong Zhe Jin"'
Autor:
Srikar Rao, Jeong A. Lee, Dae Hong Shin, Sang Kook Lee, Hea Ok Kim, Moon Woo Chun, Heng T. Duong, Hyung Ryong Moon, Prashantha Gunaga, Ji Young Jung, Zhan-Guo Gao, Dong Zhe Jin, Kenneth A. Jacobson, Lak Shin Jeong, Hyuk Woo Lee
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:4718-4730
A large series of N6-substituted-4′-thioadenosines were synthesized starting from d -gulonic-γ-lactone, and structure–activity relationships were studied at the human A3 and other subtypes of adenosine receptors (ARs). 2-Chloro-substituted and 2
Autor:
Dong Zhe Jin, Hea Ok Kim, Prashantha Gunaga, Moon Woo Chun, Hyung Ryong Moon, Dae-Kee Kim, Sung Hee Kwon, Lak Shin Jeong
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:1101-1109
The present work describes the asymmetric synthesis of D- and L-apio-2',3'-dideoxynucleoside analogues, 4 and 5 with 2'-hydroxyl group via a common intermediate 9, starting from D-galactose. Stereoselective dihydroxylation and deoxygenation through r
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 44(7)
Taking 3'-Me-Ado (3'-methyladenosine) and Cladribine as the leading compounds, seventeen 3'-C-methyl-furanonucleosides were designed and synthesized. All the structures were confirmed by 1H NMR and MS. The target compounds were tested in vitro agains
Autor:
Dae Hong Shin, Kenneth A. Jacobson, Lak Shin Jeong, Dong Zhe Jin, Jeong A. Lee, Hea Ok Kim, Moon Woo Chun, Hyung Ryong Moon, Heng T. Duong, Changrui Lu, Sang Kook Lee, Hyuk Woo Lee, Prashantha Gunaga, Zhan-Guo Gao
Publikováno v:
Journal of medicinal chemistry. 49(1)
We have established structure-activity relationships of novel 4'-thionucleoside analogues as the A(3) adenosine receptor (AR) agonists. Binding affinity, selectivity toward other AR subtypes, and efficacy in inhibition of adenylate cyclase were studi
Autor:
Yong-Chul Kim, Prashantha Gunaga, Dae Hong Shin, Neli Melman, Hyung Ryong Moon, Zhan-Guo Gao, Hea Ok Kim, Moon Woo Chun, Dong Zhe Jin, Kenneth A. Jacobson, Lak Shin Jeong
Publikováno v:
Journal of medicinal chemistry. 46(18)
4'-Thio analogues 3-5 of Cl-IB-MECA (2) (K(i) = 1.0 +/- 0.2 nM at the human A(3) adenosine receptor) were synthesized from d-gulono-gamma-lactone via 4-thioribosyl acetate 14 as the key intermediate. All synthesized 4'-thionucleosides exhibited highe
Publikováno v:
ACM Transactions on Sensor Networks; Aug2023, Vol. 19 Issue 3, p1-23, 23p
Publikováno v:
2016 IEEE International Conference on High Voltage Engineering & Application (ICHVE); 2016, p1-4, 4p
Autor:
Qiu, Miaohan, Li, Yi, Li, Jing, Xu, Kai, Jing, Quanmin, Dong, Shaohong, Jin, Zhe, Zhao, Pitian, Xu, Bo, Han, Yaling
Publikováno v:
Catheterization & Cardiovascular Interventions; Mar2017 Supplement, Vol. 89 Issue S1, p565-573, 9p
Autor:
Qingshan Liu, Hanzi Wang, Zhanyu Ma, Weishi Zheng, Hongbin Zha, Xilin Chen, Liang Wang, Rongrong Ji
The 13-volume set LNCS 14425-14437 constitutes the refereed proceedings of the 6th Chinese Conference on Pattern Recognition and Computer Vision, PRCV 2023, held in Xiamen, China, during October 13–15, 2023. The 532 full papers presented in these v