Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Dong Yun Zhan"'
Autor:
Rajesh Katare, James T. Pearson, Jason Kar-Sheng Lew, Melanie Wei, Hirotsugu Tsuchimouchi, Cheng-Kun Du, Dong-Yun Zhan, Keiji Umetani, Mikiyasu Shirai, Daryl O. Schwenke
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Background: The causal factors underpinning the onset and progression of diabetic heart disease (DHD) remain to be fully elucidated. Myocardial function is critically dependent on optimal coronary blood flow. Considering vascular disease occurs early
Externí odkaz:
https://doaj.org/article/074be22372744553be93780c7e6c2f11
Autor:
Hirotsugu Tsuchimochi, Takashi Sonobe, Keiji Umetani, Amanda J. Edgley, Mikiyasu Shirai, Dong Yun Zhan, Tadakatsu Inagaki, Jennifer P. Ngo, Yutaka Fujii, Hamish P Thambyah, James T. Pearson, Yi Ching Chen, Mark T. Waddingham, Cheng-Kun Du, Connie P. C. Ow, Darren J. Kelly, Vijayakumar Sukumaran
Publikováno v:
Clinical Science. 135:327-346
A high salt intake exacerbates insulin resistance, evoking hypertension due to systemic perivascular inflammation, oxidative-nitrosative stress and endothelial dysfunction. Angiotensin-converting enzyme inhibitor (ACEi) and angiotensin receptor block
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a8c1dd511f90ba30d7f2447eb245e1
https://doi.org/10.1042/cs20201441
https://doi.org/10.1042/cs20201441
Autor:
Melanie Wei, Meihua Jin, Jason Kar Sheng Lew, Eugene Saw, Mikiyasu Shirai, Dong Yun Zhan, Cheng-Kun Du, Keiji Umetani, James T. Pearson, Rajesh Katare, Daryl O. Schwenke, Nilanjan Ghosh, Hirotsugu Tsuchimochi
Publikováno v:
Circ Res
Rationale: Diabetic heart disease (DHD) is a debilitating manifestation of type 2 diabetes mellitus. Exercise has been proposed as a potential therapy for DHD, although the effectiveness of exercise in preventing or reversing the progression of DHD r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21917217592d1aec1176fcf5f289937d
https://doi.org/10.1161/circresaha.120.317604
https://doi.org/10.1161/circresaha.120.317604
Autor:
Masaki Arioka, Tatsuya Yoshihara, Rasha M. S. M. Mohamed, Toshiyuki Sasaguri, Cheng-Kun Du, Dong Yun Zhan, Sachio Morimoto, Islam A.A.E.-H. Ibrahim, Fumi Takahashi-Yanaga
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H1808-H1815
Glycogen synthase kinase-3β (GSK-3β) plays a central role in both cardiac physiology and pathology. Herein we want to clarify the role of GSK-3β in familial dilated cardiomyopathy. We generated a mouse model carrying a heterozygous knockout mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0df1132ecc06e401c3f29d0e36659f
https://doi.org/10.1152/ajpheart.00771.2015
https://doi.org/10.1152/ajpheart.00771.2015
Autor:
Ryo Tanaka, Takuro Arimura, Taisuke Ishikawa, Akinori Kimura, Shu Nakao, Cheng-Kun Du, Dong Yun Zhan, Takeharu Hayashi, Masayoshi Kuwahara, Antoine Muchir, Sachio Morimoto, Yoshihisa Yamane, Noboru Machida
Publikováno v:
AJP-Heart and Circulatory Physiology
AJP-Heart and Circulatory Physiology, 2018, 314 (6), pp.H1192-H1202. ⟨10.1152/ajpheart.00696.2017⟩
AJP-Heart and Circulatory Physiology, 2018, 314 (6), pp.H1192-H1202. ⟨10.1152/ajpheart.00696.2017⟩
Mutations in genes encoding components of the sarcomere cause cardiomyopathy, which is often associated with abnormal Ca2+sensitivity of muscle contraction. We have previously shown that a heart-specific myosin light chain phosphatase small subunit (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e762464fdc55821fe6553f4719d6a9ed
https://hal.science/hal-03859515
https://hal.science/hal-03859515
Autor:
Pearson, James T., Thambyah, Hamish P., Waddingham, Mark T., Inagaki, Tadakatsu, Sukumaran, Vijayakumar, Ngo, Jennifer P., Ow, Connie P. C., Takashi Sonobe, Yi Ching Chen, Edgley, Amanda J., Yutaka Fujii, Cheng-Kun Du, Dong-Yun Zhan, Keiji Umetani, Kelly, Darren J., Hirotsugu Tsuchimochi, Mikiyasu Shirai
Publikováno v:
Clinical Science; Jan2021, Vol. 135 Issue 2, p327-346, 20p
Autor:
Mikiyasu Shirai, Mark T. Waddingham, Takashi Sonobe, Dong Yun Zhan, Yi Ching Chen, Hirotsugu Tsuchimochi, Tadakatsu Inagaki, H Thambyah, Cheng-Kun Du, Amanda J. Edgley, V Sukumaran, James T. Pearson, Keiji Umetani
Publikováno v:
European Heart Journal. 38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f453b3dc7320aba595e2849a6e534860
https://doi.org/10.1093/eurheartj/ehx504.p3478
https://doi.org/10.1093/eurheartj/ehx504.p3478
Publikováno v:
Acta Physiologica. 210:823-831
Aim Calpain activation has a putative role in ischaemia-reperfusion injury of cardiomyocytes. This study clarified the in vivo contribution of calpain to disruption of cardiomyocyte sarcolemma during ischaemia and after reperfusion in anaesthetized r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da809d513c5dfe7a962f0261fc502449
https://doi.org/10.1111/apha.12205
https://doi.org/10.1111/apha.12205
Autor:
Shuji Shimizu, Takashi Sonobe, Dong Yun Zhan, Hirotsugu Tsuchimochi, Toru Kawada, Cheng-Kun Du, Mikiyasu Shirai, Tsuyoshi Akiyama
Publikováno v:
Autonomic Neuroscience. 176:91-94
We applied a microdialysis technique to the left ventricular myocardium of anesthetized mice and tried to monitor acetylcholine (ACh) release from cardiac vagal nerves. Transection of bilateral cervical vagal nerves decreased dialysate ACh concentrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2288b20f7a39724eac145a8010fc1dd2
https://doi.org/10.1016/j.autneu.2013.02.014
https://doi.org/10.1016/j.autneu.2013.02.014
Autor:
Mikiyasu Shirai, Toru Kawada, Shuji Shimizu, Sachio Morimoto, James T. Pearson, Dong Yun Zhan, Tsuyoshi Akiyama, Cheng-Kun Du
Publikováno v:
Autonomic neuroscience : basicclinical. 205
The aim of this study was to evaluate cardiac vagal nerve activity and identify the abnormality of cardiac vagal control in heart failure caused by dilated cardiomyopathy (DCM) using a knock-in mouse model with a ΔK210 mutation in the cardiac tropon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47eff49b1648bafd435d80b738dc36ac
https://pubmed.ncbi.nlm.nih.gov/28344023
https://pubmed.ncbi.nlm.nih.gov/28344023