Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Dong Yun Han"'
Autor:
Ya-Juan Wang, Xiao-Jing Di, Pei-Pei Zhang, Xi Chen, Marnie P Williams, Dong-Yun Han, Raad Nashmi, Brandon J Henderson, Fraser J Moss, Ting-Wei Mu
Publikováno v:
eLife, Vol 13 (2024)
Protein homeostasis (proteostasis) deficiency is an important contributing factor to neurological and metabolic diseases. However, how the proteostasis network orchestrates the folding and assembly of multi-subunit membrane proteins is poorly underst
Externí odkaz:
https://doaj.org/article/3c4e1af339594e16b884f8208cc9c4b6
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207948 (2018)
Biogenesis of membrane proteins is controlled by the protein homeostasis (proteostasis) network. We have been focusing on protein quality control of γ-aminobutyric acid type A (GABAA) receptors, the major inhibitory neurotransmitter-gated ion channe
Externí odkaz:
https://doaj.org/article/d146b7fd7b744215a70ac2a8c47f18c5
Autor:
Ya-Juan Wang, Xiao-Jing Di, Dong-Yun Han, Raad Nashmi, Brandon J. Henderson, Fraser J. Moss, Ting-Wei Mu
Protein homeostasis (proteostasis) deficiency is an important contributing factor to neurodegenerative, neurological, and metabolic diseases. However, how the proteostasis network orchestrates the folding and assembly of multi-subunit membrane protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cfe6d3a7a4ebc3ca4bb34747512832d
https://doi.org/10.1101/2022.10.24.513629
https://doi.org/10.1101/2022.10.24.513629
Autor:
Dong-Yun Han, Etsuko Minobe, Wu-Yang Wang, Feng Guo, Jian-Jun Xu, Li-Ying Hao, Masaki Kameyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 112, Iss 3, Pp 310-319 (2010)
The L-type Ca2+ channel (Ca V 1.2) shows clear Ca2+-dependent facilitation and inactivation. Here we have examined the effects of calmodulin (CaM) and Ca2+ on Ca2+ channel in guinea-pig ventricular myocytes in the inside-out patch mode, where rundown
Externí odkaz:
https://doaj.org/article/9742e5767dff4ab78135ee3d4bf1508e
Autor:
Li-Ying Hao, Wu-Yang Wang, Etsuko Minobe, Dong-Yun Han, Jian-Jun Xu, Asako Kameyama, Masaki Kameyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 111, Iss 4, Pp 416-425 (2009)
In this study, we investigated the roles of calmodulin kinase II (CaMKII) and calmodulin (CaM) in the reversal of run-down of L-type Ca2+ channels. Single Ca2+-channel activities in guinea-pig ventricular myocytes were recorded using the patch-clamp
Externí odkaz:
https://doaj.org/article/57faa8652fe141c281356f308b6de87c
Publikováno v:
Oil Shale. 2018, Vol. 35 Issue 2, p183-194. 12p.
Autor:
Panjamaporn Sangwung, Ting Wei Mu, Renae Brown, Yajuan Wang, Meng Wang, Dong-Yun Han, Angela L. Whittsette, Angelo Keramidas, Edmund Cotter, Xiao-Jing Di, Joseph W. Lynch
Publikováno v:
Cell Chemical Biology. 28:46-59.e7
Proteostasis deficiency in mutated ion channels leads to a variety of ion channel diseases that are caused by excessive endoplasmic reticulum-associated degradation (ERAD) and inefficient membrane trafficking. We investigated proteostasis maintenance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d54f1cf8366c55f3c96f23b636ab3a
https://doi.org/10.1016/j.chembiol.2020.08.012
https://doi.org/10.1016/j.chembiol.2020.08.012
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0207948 (2018)
PLoS ONE, Vol 13, Iss 11, p e0207948 (2018)
Biogenesis of membrane proteins is controlled by the protein homeostasis (proteostasis) network. We have been focusing on protein quality control of γ-aminobutyric acid type A (GABAA) receptors, the major inhibitory neurotransmitter-gated ion channe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051e61be3a5849e9491c2c6aa63faf6e
https://pubmed.ncbi.nlm.nih.gov/30481215
https://pubmed.ncbi.nlm.nih.gov/30481215
Publikováno v:
Journal of Biological Chemistry. 290:325-337
GABAA receptors are the primary inhibitory ion channels in the mammalian central nervous system. The A322D mutation in the α1 subunit results in its excessive endoplasmic reticulum-associated degradation at the expense of plasma membrane trafficking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a406eb705d03c70a616bf8d0e1849178
https://doi.org/10.1074/jbc.m114.580324
https://doi.org/10.1074/jbc.m114.580324
Publikováno v:
The Journal of Membrane Biology. 248:197-204
Ion channel expression and activity may be affected during tumor development and cancer growth. Activation of potassium (K(+)) channels in human breast cancer cells is reported to be involved in cell cycle progression. In this study, we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b93ce834c7a6848b14251d905b5168
https://doi.org/10.1007/s00232-014-9757-6
https://doi.org/10.1007/s00232-014-9757-6