Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Dong Oh Seo"'
Autor:
Dong-oh Seo, David M. Holtzman
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 1, Pp 86-94 (2024)
Abstract Alzheimer’s disease (AD) is a fatal progressive neurodegenerative disease. Despite tremendous research efforts to understand this complex disease, the exact pathophysiology of the disease is not completely clear. Recently, anti-Aβ antibod
Externí odkaz:
https://doaj.org/article/e6605383c6944a45875ab9156245acf5
Autor:
Dong-oh Seo, David O’Donnell, Nimansha Jain, Jason D. Ulrich, Jasmin Herz, Yuhao Li, Mackenzie Lemieux, Jiye Cheng, Hao Hu, Javier R. Serrano, Xin Bao, Emily Franke, Maria Karlsson, Martin Meier, Su Deng, Chandani Desai, Hemraj Dodiya, Janaki Lelwala-Guruge, Scott A. Handley, Jonathan Kipnis, Sangram S. Sisodia, Jeffrey I. Gordon, David M. Holtzman
Publikováno v:
Science. 379
Tau-mediated neurodegeneration is a hallmark of Alzheimer’s disease. Primary tauopathies are characterized by pathological tau accumulation and neuronal and synaptic loss. Apolipoprotein E (ApoE)–mediated neuroinflammation is involved in the prog
Autor:
Dong‐oh Seo, David O'Donnell, Nimansha Jain, Jason D Ulrich, Jasmin Herz, Mackenzie Lemieux, Jack G. Stanley, Emily Franke, Javier R. Serrano, Xin Bao, Maria Karlsson, Marty Meier, Chandani Desai, Janaki Lelwala‐Guruge, Yuhao Li, Yang Shi, Chao Wang, Jiye Cheng, Kalil Alves de Lima, Hemraj B. Dodiya, Matthew Hibberd, Nicholas Griffin, Scott Handley, Jonathan Kipnis, Sangram S. Sisodia, Jeffrey I. Gordon, David M. Holtzman
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Dong‐oh Seo, Jack G. Stanley, Yang Shi, Chao Wang, Javier R. Serrano, Xin Bao, David O'Donnell, Janaki Lelwala‐Guruge, Nicholas Griffin, Marty Meier, Hemraj B. Dodiya, Sangram S. Sisodia, Jeffrey I. Gordon, David M. Holtzman
Publikováno v:
Alzheimer's & Dementia. 17
Autor:
Dong Oh Seo, David M. Holtzman
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
More than 300 years ago, Antony van Leewenhoeck first described observing single-celled microorganisms, which he termed “animalcules,” examining his saliva under a microscope. Although the idea of the coexistence of microorganisms in our body is
Autor:
Adrian M. Gomez, Tammy K. Nguyen, Eric T. Zhang, Bryce K. Kan, Sean C. Piantadosi, Dong Oh Seo, David J. Marcus, Li Xia, Michael R. Bruchas, Laura E. Motard
Publikováno v:
Neuron
Summary Dysregulation in contextual processing is believed to affect several forms of psychopathology, such as post-traumatic stress disorder (PTSD). The dentate gyrus (DG), a subregion of the hippocampus, is thought to be an important brain region f
Autor:
Dong Oh Seo, Michael R. Bruchas
Publikováno v:
Nature Neuroscience. 20:1517-1519
Physiological and optogenetic dissection of discrete locus coeruleus neuronal populations reveals a functional disassociation, with heterogeneous engagement of locus coeruleus neurons in either fear learning or extinction models.
Publikováno v:
Behavioral neuroscience. 132(1)
We examined the enduring effects of predictable versus unpredictable fear conditioning early in life on memory and relearning in adulthood. At postnatal Day 17 or 25 (P17 or P25), rats either remained naive, or were fear conditioned using paired (pre
Autor:
Xing Sheng, Gabe G. Sobczak, Xin Ning, Debashis Chanda, Rongxue Ma, Lan Yin, Luyao Lu, Grace Pakeltis, Dionnet L. Bhatti, Tian Sang, Dong Oh Seo, Mantian Xue, Michael R. Bruchas, Xinying Wang, John A. Rogers, Li Xia, Abraham Vázquez-Guardado, Philipp Gutruf, Xinru Shen, Hao Zhang
Publikováno v:
Proceedings of the National Academy of Sciences. 115
Capabilities for recording neural activity in behaving mammals have greatly expanded our understanding of brain function. Some of the most sophisticated approaches use light delivered by an implanted fiber-optic cable to optically excite genetically
Publikováno v:
Cell Res