Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Dong Ki Choi"'
Autor:
Seung-Min Shin, Dong-Ki Choi, Keunok Jung, Jeomil Bae, Ji-sun Kim, Seong-wook Park, Ki-Hoon Song, Yong-Sung Kim
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Oncogenic RAS mutants are key anti-cancer targets as KRas mutations are very frequent in human cancers. Here, the authors engineer a cytosol-penetrating anti-Ras antibody and demonstrate its ability to block RAS-effector protein interactions inhibiti
Externí odkaz:
https://doaj.org/article/f92bfa18577140acbe2a6429590c88a9
Correlation Between HAZ Microstructure and Low Temperature Impact Toughness of Bainitic Steel Plates
Autor:
Yong Jai Kwon, Jung Gu Lee, Woo Hyuk Choi, Sung Kyu Cho, Dong Ki Choi, Yang Gon Kim, Sang Yong Shin, Hun Lee
Publikováno v:
Journal of Welding and Joining. 39:269-277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e610702bd04d9ec5496c37f4f23e06dc
https://doi.org/10.5781/jwj.2021.39.3.5
https://doi.org/10.5781/jwj.2021.39.3.5
Autor:
James Palacino, Pedro Lee, Hangyeol Jeong, Yeonjoon Kim, Yoojin Song, Uttapol Permpoon, Wesley Wong, Chen Bai, Nathan Fishkin, Khuloud Takouri, Eunjun Yu, Yong Yi, Anna Skaletskaya, Min-Soo Kim, Da-Yeong Kim, Dong-Ki Choi, Peter U. Park
Publikováno v:
Cancer Research. 83:2700-2700
Targeted protein degraders (TPDs) have expanded the breadth of therapeutic options through both their catalytic mechanism of action and ability to degrade previously “undruggable” target proteins. Prior reports of small-molecule GSPT1 degraders s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71b86ce68b21ee643f8dfae287c1ca67
https://doi.org/10.1158/1538-7445.am2023-2700
https://doi.org/10.1158/1538-7445.am2023-2700
Autor:
Joanne Lim, Anna Skaletskaya, Uttapol Permpoon, Yeonjoon Kim, Shikha Saini, Khuloud Takrouri, Zinaida Ribkovskaia, Palash Bhar, Nathan Fishkin, Dong-Ki Choi, Ji Hyun Park, James Palacino, Peter U. Park
Publikováno v:
Cancer Research. 83:4436-4436
It is well-established that T cells play a key role in the success of cancer immunotherapies. The goals of T cell-targeting therapies have been to restore the effector function of tumor-specific T cells that are either dysfunctional due to the immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0ac3320da913310739ac2e45ee0f474
https://doi.org/10.1158/1538-7445.am2023-4436
https://doi.org/10.1158/1538-7445.am2023-4436
Autor:
James Palacino, Pedro Lee, Hangyeol Jeong, Yeonjoon Kim, Yoojin Song, Uttapol Permpoon, Wesley Wong, Chen Bai, Nathan Fishkin, Khuloud Takrouri, Eunjin Yu, Yong Yi, Anna Skaletskaya, Ki-Hwan Chang, Min-Soo Kim, Da-Yeong Kim, Dong-Ki Choi, Peter U Park
Publikováno v:
Blood. 140:3061-3062
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a269d96e6caa27fb8cac688926936eb0
https://doi.org/10.1182/blood-2022-168936
https://doi.org/10.1182/blood-2022-168936
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145349 (2015)
Immunoglobulin Fc heterodimers, which are useful scaffolds for the generation of bispecific antibodies, have been mostly generated through structure-based rational design methods that introduce asymmetric mutations into the CH3 homodimeric interface
Externí odkaz:
https://doaj.org/article/13ca798dcff2483eb9833dfda3577f2d
Autor:
James Palacino, Chen Bai, Yong Yi, Anna Skaletskaya, Khuloud Takrouri, Wesley Wong, Min-Soo Kim, Dong-Ki Choi, Da-Young Kim, Yeonhee Yang, Jiae Kook, Pedro Lee, Hangyeol Jeong, Sang-Mi Jee, Jiyun Park, Ki-Hwan Chang, Nathan Fishkin, Peter U. Park
Publikováno v:
Cancer Research. 82:3933-3933
Targeted protein degradation (TPD) molecules, including IMiD-based molecular glues and heterobifunctional degraders have expanded the breadth of therapeutic options through both their catalytic mechanism of action and ability to degrade previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3721e0df43cd095effb959ab01db3fd9
https://doi.org/10.1158/1538-7445.am2022-3933
https://doi.org/10.1158/1538-7445.am2022-3933
Autor:
Yong Beom Cho, Yong Sung Kim, Seong-Wook Park, Dong-Ki Choi, Sei-Yong Jun, Ji-Sun Kim, Dakeun Lee, Hye-Jin Kweon, Seung-Min Shin
Publikováno v:
Science Advances
We report a potent pan-RAS–targeting antibody and the corresponding therapeutic strategy against RAS mutant tumors.
Oncogenic RAS mutant (RASMUT) proteins have been considered undruggable via conventional antibody regimens owing to the intrace
Oncogenic RAS mutant (RASMUT) proteins have been considered undruggable via conventional antibody regimens owing to the intrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58bc894468003c026b00180512177b8f
http://europepmc.org/articles/PMC6962039
http://europepmc.org/articles/PMC6962039
Autor:
Aeyung Kim, Tae-Hwan Shin, Seung-Min Shin, Chuong D Pham, Dong-Ki Choi, Myung-Hee Kwon, Yong-Sung Kim
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51813 (2012)
Cellular internalization of bacteriophage by surface-displayed cell penetrating peptides has been reported, though the underlying mechanism remains elusive. Here we describe in detail the internalization mechanism and intracellular trafficking and st
Externí odkaz:
https://doaj.org/article/5b6a7e0d38bc4dd4b01403b342287f0d
Autor:
Hyun Woo Kim, Dong-Ki Choi, Eun-Hye Kim, Yong Sung Kim, Edward D. Chan, Siyoung Lee, Areum Kwak, In Ae Kim, Hyunjhung Jhun, Tam T. Nguyen, Xiyuan Bai, Kwang Ha Yoo, Soohyun Kim, Gaae Gil, Sinae Kim, Youngmin Lee
Publikováno v:
Immune Network
The induction of interleukin (IL)-32 in bone marrow (BM) inflammation is crucial in graft versus host disease (GvHD) that is a common side effect of allogeneic BM transplantation. Clinical trials on α-1 antitrypsin (AAT) in patients with GvHD are ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30245bb88e56942ee8472fac74bce5f7
http://europepmc.org/articles/PMC5407983
http://europepmc.org/articles/PMC5407983