Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Dong Ik, Park"'
Autor:
Vanessa Lopes-Rodrigues, Pia Boxy, Eunice Sim, Dong Ik Park, Michael Habeck, Josep Carbonell, Annika Andersson, Diana Fernández-Suárez, Poul Nissen, Anders Nykjær, Lilian Kisiswa
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-13 (2023)
Abstract Cytosine arabinoside (AraC) is one of the main therapeutic treatments for several types of cancer, including acute myeloid leukaemia. However, after a high-dose AraC chemotherapy regime, patients develop severe neurotoxicity and cell death i
Externí odkaz:
https://doaj.org/article/4188c53e5bda44dd986f66f416d2e3a1
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-4 (2020)
Abstract Synaptic proteins play an important role for the regulation of synaptic plasticity. Numerous studies have identified and revealed individual synaptic protein functions using protein overexpression or deletion. In neuropathic pain nociceptive
Externí odkaz:
https://doaj.org/article/761f8e41f7354c25a381da33eb28635d
Publikováno v:
Zoological Research. 44:30-42
Fluoxetine (Prozac™) is the only antidepressant approved by the US Food and Drug Administration (FDA) for the treatment of major depressive disorder (MDD) in children. Despite its considerable efficacy as a selective serotonin reuptake inhibitor, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac26a81a8636c54905f407ee99607b69
https://doi.org/10.24272/j.issn.2095-8137.2022.196
https://doi.org/10.24272/j.issn.2095-8137.2022.196
Autor:
Frederik Dethloff, Fernando Vargas, Emmanuel Elijah, Robert Quinn, Dong Ik Park, David P. Herzog, Marianne B. Müller, Emily C. Gentry, Rob Knight, Antonio Gonzalez, Pieter C. Dorrestein, Christoph W. Turck
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Recent interest in the role of microbiota in health and disease has implicated gut microbiota dysbiosis in psychiatric disorders including major depressive disorder. Several antidepressant drugs that belong to the class of selective serotonin reuptak
Externí odkaz:
https://doaj.org/article/77016f953b8449c68daf47c7328dc1b7
Autor:
Hyoung-Gon Ko, Jun-Hyeok Choi, Dong Ik Park, SukJae Joshua Kang, Chae-Seok Lim, Su-Eon Sim, Jaehoon Shim, Ji-Il Kim, Siyong Kim, Tae-Hyeok Choi, Sanghyun Ye, Jaehyun Lee, Pojeong Park, Somi Kim, Jeehaeh Do, Jihye Park, Md Ariful Islam, Hyun Jeong Kim, Christoph W. Turck, Graham L. Collingridge, Min Zhuo, Bong-Kiun Kaang
Publikováno v:
Cell Reports, Vol 22, Iss 3, Pp 748-759 (2018)
Peripheral nerve injury can induce pathological conditions that lead to persistent sensitized nociception. Although there is evidence that plastic changes in the cortex contribute to this process, the underlying molecular mechanisms are unclear. Here
Externí odkaz:
https://doaj.org/article/ab90b55a2eb741d9829cc87725633ded
Autor:
Anna Tkachev, Elena Stekolshchikova, Daniil M. Bobrovskiy, Nickolay Anikanov, Polina Ogurtsova, Dong Ik Park, Anja K. E. Horn, Daria Petrova, Ekaterina Khrameeva, Mari S. Golub, Christoph W. Turck, Philipp Khaitovich
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8089 (2021)
Fluoxetine is an antidepressant commonly prescribed not only to adults but also to children for the treatment of depression, obsessive-compulsive disorder, and neurodevelopmental disorders. The adverse effects of the long-term treatment reported in s
Externí odkaz:
https://doaj.org/article/f895fec8ff5b457cb67c95f9c71d2310
Autor:
Zuzanna Misiewicz, Stella Iurato, Natalia Kulesskaya, Laura Salminen, Luis Rodrigues, Giuseppina Maccarrone, Jade Martins, Darina Czamara, Mikaela A Laine, Ewa Sokolowska, Kalevi Trontti, Christiane Rewerts, Bozidar Novak, Naama Volk, Dong Ik Park, Eija Jokitalo, Lars Paulin, Petri Auvinen, Vootele Voikar, Alon Chen, Angelika Erhardt, Christoph W Turck, Iiris Hovatta
Publikováno v:
PLoS Genetics, Vol 15, Iss 9, p e1008358 (2019)
Stressful life events are major environmental risk factors for anxiety disorders, although not all individuals exposed to stress develop clinical anxiety. The molecular mechanisms underlying the influence of environmental effects on anxiety are large
Externí odkaz:
https://doaj.org/article/cc92368b12514335bdd3c2981c2821eb
Publikováno v:
Park, D, Novak, B, Yan, Y, Kaya, M E & Turck, C W 2020, ' Paroxetine binding and activation of phosphofructokinase implicates energy metabolism in antidepressant mode of action ', Journal of Psychiatric Research, vol. 129, pp. 8-14 . https://doi.org/10.1016/j.jpsychires.2020.05.033
Selective serotonin reuptake inhibitors (SSRIs) are the predominant drugs prescribed for Major Depressive Disorder. The immediate pharmacological target of SSRIs is the serotonin transporter. However, the delayed therapeutic effect and high rate of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3330127d9c4494f261831bd4830f2c35
https://pubmed.ncbi.nlm.nih.gov/32540574
https://pubmed.ncbi.nlm.nih.gov/32540574
Publikováno v:
Molecular Brain
Molecular Brain, Vol 13, Iss 1, Pp 1-4 (2020)
Molecular Brain, Vol 13, Iss 1, Pp 1-4 (2020)
Synaptic proteins play an important role for the regulation of synaptic plasticity. Numerous studies have identified and revealed individual synaptic protein functions using protein overexpression or deletion. In neuropathic pain nociceptive stimuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c1ebd6404dbb3b255daf1c8dd9f68c
https://doi.org/10.1186/s13041-020-0564-y
https://doi.org/10.1186/s13041-020-0564-y
Autor:
Dong Ik Park
Publikováno v:
Park, D 2020, Genomics, transcriptomics, proteomics and big data analysis in the discovery of new diagnostic markers and targets for therapy development . in M Ilieva & W K-W Lau (eds), Autism . Elsevier, Progress in Molecular Biology and Translational Science, vol. 173, pp. 61-90 . https://doi.org/10.1016/bs.pmbts.2020.04.017
Highly complex endophenotypes and underlying molecular mechanisms have prevented effective diagnosis and treatment of autism spectrum disorder. Despite extensive studies to identify relevant biosignatures, no biomarker and therapeutic targets are ava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed6f37778e9972283dab8f2a5a3cda8
https://pure.au.dk/portal/da/publications/genomics-transcriptomics-proteomics-and-big-data-analysis-in-the-discovery-of-new-diagnostic-markers-and-targets-for-therapy-development(e2da7c36-cf17-4ebe-9b16-a566a63adce7).html
https://pure.au.dk/portal/da/publications/genomics-transcriptomics-proteomics-and-big-data-analysis-in-the-discovery-of-new-diagnostic-markers-and-targets-for-therapy-development(e2da7c36-cf17-4ebe-9b16-a566a63adce7).html
