Výsledky vyhledávání - "Dong Hoon Han"

Akademický článek

Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation

Autor: Won Hoon Choi, Stefanie A. H. de Poot, Jung Hoon Lee, Ji Hyeon Kim, Dong Hoon Han, Yun Kyung Kim, Daniel Finley, Min Jae Lee

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)

The proteasome plays a key role in proteostasis by mediating the degradation of ubiquitinated substrates. Here the authors show that an open-gate mutant of the proteasome is hyperactive towards a subset of substrates and can effectively delay the acc

Externí odkaz: https://doaj.org/article/69d5789905d74b3b8111cc7dc208f815

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Akademický článek

A case of partial trisomy 3p syndrome with rare clinical manifestations

Autor: Dong Hoon Han, Ji Young Chang, Woo In Lee, Chong Woo Bae

Publikováno v: Korean Journal of Pediatrics, Vol 55, Iss 3, Pp 107-110 (2012)

Partial trisomy 3p results from either unbalanced translocation or de novo duplication. Common clinical features consist of dysmorphic facial features, congenital heart defects, psychomotor and mental retardation, abnormal muscle tone, and hypoplasti

Externí odkaz: https://doaj.org/article/8e072f13465c4ae5b53f9c30e13d1587

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Akademický článek

UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells.

Autor: Jee Young An, Euna Kim, Adriana Zakrzewska, Young Dong Yoo, Jun Min Jang, Dong Hoon Han, Min Jae Lee, Jai Wha Seo, Yong Jun Lee, Tae-You Kim, Dirk G de Rooij, Bo Yeon Kim, Yong Tae Kwon

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e37414 (2012)

The N-end rule pathway is a proteolytic system in which its recognition components (N-recognins) recognize destabilizing N-terminal residues of short-lived proteins as an essential element of specific degrons, called N-degrons. The RING E3 ligases UB

Externí odkaz: https://doaj.org/article/d39895ed2bc647f1800886811d1a09d8

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