Výsledky vyhledávání - "Dong Eok Lee"

Differences in Proportion of N-acetyllactosamine and O-acetylated Sialic Acid Have No Significant Effect on the Pharmacokinetics and Biological Activity of Darbepoetin Alfa

Autor: Won Jeong Lee, Hookeun Oh, Inseong Choi, Keunho Lee, Hyunwoo Shin, Yoon Jung Lee, Jeehye Park, Yoo Hee Yang, Gyong-Sik Ha, Dong-Eok Lee, Kang-Yell Choi, Eunyoung Choi

Publikováno v: Biotechnology and Bioprocess Engineering. 27:244-252

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e3dd755fe17c3d23d3e216e7e14ab41
https://doi.org/10.1007/s12257-021-0042-0

Zobrazit plný text záznamu

Purification of antibody fragments for the reduction of charge variants using cation exchange chromatography

Autor: Jung Min Yoo, Mi Kyung Park, Sung-Muk Kang, Dong Eok Lee, Min-A Choi, Hong Jai Lee, Gyong-Sik Ha, Chung Min Lee, Kyung Hwa Kim, Baik Lin Seong

Publikováno v: Journal of Chromatography B. 1080:20-26

Recently, antibody fragments have been studied as therapeutic agents because they lack Fc effector function while having affinity similar to their original monoclonal antibody and can be produced using E. coli. Antibody fragments can be purified usin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c6d45cb0deb0b32dc78453f140a80b
https://doi.org/10.1016/j.jchromb.2018.01.030

Zobrazit plný text záznamu

Enhanced expression of soluble antibody fragments by low-temperature and overdosing with a nitrogen source

Autor: Jae Hee Lee, Gyong Sik Ha, Kim Se Jun, Chung Min Lee, Yong Uk Shin, Lee Jaemin, Sung In Lim, Yoo Hee Yang, Ju Eun Kim, Chan wha Kim, Lee Gyung-Hwa, Dong Eok Lee

Publikováno v: Enzyme and microbial technology. 115

Escherichia coli has been a primary host for the prokaryotic production of antibody fragments (Fabs) and has contributed to several successes in the pharmaceutical industry. Nevertheless, the requirement of disulfide bonds often results in low-yield

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751dc0443e628e98ffb962a71e31a076
https://pubmed.ncbi.nlm.nih.gov/29859607

Zobrazit plný text záznamu

The prolonged half-lives of new erythropoietin derivatives via peptide addition

Autor: Dong Eok Lee, Byung Jhip Ha, Myung Suk Oh, Ook Joon Yoo, Wonseok Son

Publikováno v: Biochemical and Biophysical Research Communications. 339:380-385

Erythropoietin, or Epo, is a hematopoietic cytokine that promotes erythropoiesis, and recombinant human Epo has been used in the treatment of anemia in various chronic diseases. Here, we have constructed novel Epo derivatives with prolonged half-live

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7607864c31fb48f12262b5f812d3c1
https://doi.org/10.1016/j.bbrc.2005.11.034

Zobrazit plný text záznamu

Altered Oral Absorption of Alcohol by Combined Aqueous Extracts of Four Herbal Plants in Rats

Autor: Eun-Seok Park, Kang Ro Lee, Sun Dong Yoo, Hun Jun, Beom Soo Shin, Dong-Eok Lee

Publikováno v: Journal of Toxicology and Environmental Health, Part A. 68:2219-2226

This study examined the effect of combined aqueous extracts (BHR) of Ginko biloba, Mentha arvensis var. piperascens, Citrus unshiu, and Pueraria lobata var. chinensis on oral absorption of alcohol in rats. The rats were pretreated with BHR, placebo s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0abeac8d3cdb9bfe73a4916e539b896
https://doi.org/10.1080/15287390500182081

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání