Výsledky vyhledávání - "Dong‑Hoon Jin"

Akademický článek

Mutant PIK3CA as a negative predictive biomarker for treatment with a highly selective PIM1 inhibitor in human colon cancer

Autor: Yoon Sun Park, Joseph kim, Yea Seong Ryu, Jai-Hee moon, Yu Jin shin, Jeong Hee kim, Seung-Woo hong, Soo-A jung, Seul lee, Seung-Mi kim, Dae Hee lee, Do Yeon kim, Hyeseon yun, Ji-Eun you, Dong Il yoon, Chul Hee kim, Dong-In koh, Dong-Hoon jin

Publikováno v: Cancer Biology & Therapy, Vol 24, Iss 1 (2023)

Significant improvement in targeted therapy for colorectal cancer (CRC) has occurred over the past few decades since the approval of the EGFR inhibitor cetuximab. However, cetuximab is used only for patients possessing the wild-type oncogene KRAS, NR

Externí odkaz: https://doaj.org/article/1768709d29094b5387a1c7c373462d07

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Akademický článek

Effects of the purified dry extract of fermented ginseng BST204 on muscle fiber regeneration

Autor: Su In Jo, Yoon Sun Park, Yeeun Chang, Jai-Hee Moon, Slee Lee, Hyejin Lee, MiYeon Kim, Do Yeon Kim, SangMun Bae, Se Yeong Park, Hyeseon Yun, Ji-Eun You, Minju Im, Hae-Jung Han, Sang-Yeob Kim, Dong-Hoon Jin

Publikováno v: Biochemistry and Biophysics Reports, Vol 35, Iss , Pp 101525- (2023)

Background: Sarcopenia and muscular dystrophy are two muscle diseases. In cancer patients, cancer cachexia induces continuous weight loss and muscle loss due to the disease itself or the use of anticancer drugs. Cachexia occurs in up to 80% of cancer

Externí odkaz: https://doaj.org/article/fb152ed74c6649cf9379918e08401b26

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Akademický článek

Epigenetic regulation of miR-29a/miR-30c/DNMT3A axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cells

Autor: Yi-deun Jung, Seul-Ki Park, Dayeon Kang, Supyong Hwang, Myoung-Hee Kang, Seung-Woo Hong, Jai-Hee Moon, Jae-Sik Shin, Dong-Hoon Jin, Dalsan You, Joo-Yong Lee, Yun-Yong Park, Jung Jin Hwang, Choung Soo Kim, Nayoung Suh

Publikováno v: Redox Biology, Vol 37, Iss , Pp 101716- (2020)

The use of human mesenchymal stem cells (hMSCs) in clinical applications requires large-scale cell expansion prior to administration. However, the prolonged culture of hMSCs results in cellular senescence, impairing their proliferation and therapeuti

Externí odkaz: https://doaj.org/article/d7bdcda2461b48568d4becadd31fe34a

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Akademický článek

Bay 61-3606 Sensitizes TRAIL-Induced Apoptosis by Downregulating Mcl-1 in Breast Cancer Cells.

Autor: So-Young Kim, Sang Eun Park, Sang-Mi Shim, Sojung Park, Kyung Kon Kim, Seong-Yun Jeong, Eun Kyung Choi, Jung Jin Hwang, Dong-Hoon Jin, Christopher Doosoon Chung, Inki Kim

Publikováno v: PLoS ONE, Vol 10, Iss 12, p e0146073 (2015)

Breast cancer cells generally develop resistance to TNF-Related Apoptosis-Inducing Ligand (TRAIL) and, therefore, assistance from sensitizers is required. In our study, we have demonstrated that Spleen tyrosine kinase (Syk) inhibitor Bay 61-3606 was

Externí odkaz: https://doaj.org/article/28588cff911a4253acff81e091dad37e

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Akademický článek

Increased expression of ATG10 in colorectal cancer is associated with lymphovascular invasion and lymph node metastasis.

Autor: Yoon Kyung Jo, Seung Cheol Kim, In Ja Park, So Jung Park, Dong-Hoon Jin, Seung-Woo Hong, Dong-Hyung Cho, Jin Cheon Kim

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e52705 (2012)

BACKGROUND:Autophagy has paradoxical and complex functions in cancer development, and autophagy-related genes (ATG) are key regulators in autophagy. Until now, more than 30 different ATG proteins have been identified in yeast, and their mammalian cou

Externí odkaz: https://doaj.org/article/cd641435fab24ac1ac53b916f7738d39

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