Efficacy and safety of vunakizumab in moderate-to-severe chronic plaque psoriasis: A randomized, double-blind, placebo-controlled phase 3 trial

Autor: Yan, Kexiang, Li, Fuqiu, Bi, Xiaodong, Han, Ling, Zhang, Zhenghua, Chen, Rixin, Li, Yuye, Zhang, Litao, Wang, Xiaohua, Li, Linfeng, Lu, Jianyun, Xu, Ai'e, Yang, Sen, Lu, Yan, Sun, Jianfang, Li, Zhiming, Zhu, Xiaohong, Jiang, Meiying, Zhang, Siping, Wang, Wenqing, Li, Yanling, Meng, Zudong, Li, Hongyi, Mou, Kuanhou, Han, Xiuping, Li, Shanshan, Chen, Aijun, Li, Xin, Liu, Donghua, Zhang, Chunlei, Ji, Chao, Wang, Yu, Cheng, Hao, Cui, Xiaojing, Yao, Xiaoyan, Bai, Xiaoyan, Dong, Guangchao, Xu, Jinhua

Publikováno v: In Journal of the American Academy of Dermatology January 2025 92(1):92-99

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Ivarmacitinib, a selective Janus kinase 1 inhibitor, in patients with moderate-to-severe active rheumatoid arthritis and inadequate response to conventional synthetic DMARDs: results from a phase III randomised clinical trial.

Autor: Liu J; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Beijing, China., Jiang Y; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Beijing, China., Zhang S; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Beijing, China., Liu S; Department of Rheumatology & Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Su J; Department of Rheumatology & Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Lin C; Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China., He X; Department of Rheumatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, China., Wu R; Department of Rheumatology and Immunology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China., Yang L; Department of Rheumatology and Immunology, Zhengzhou Central Hospital, Zhengzhou, China., Liu H; Rheumatology Department, Qilu Hospital of Shandong University, Jinan, China., Duan X; Rheumatology and Immunology, The Second Affiliated Hospital of Nanchang University, Nanchang, China., Xu S; Rheumatology and Immunology Department, The First Affiliated Hospital of Anhui Medical University, Hefei, China., Luo H; Department of Rheumatology and Immunology, Xiangya Hospital, Central South University, Changsha, China., Liu J; Department of Rheumatology and Immunology Research Institute, Affiliated Hospital of North Sichuan Medical College, Nanchong, China., Xie Q; Department of Rheumatology and Immunology, West China Hospital of Sichuan University, Chengdu, China., Mi C; Department of Rheumatology and Clinical Immunology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China., Chen L; Department of Rheumatic Immunity, Jilin Province People's Hospital, Changchun, China., Zhang N; Rheumatology, Shengjing Hospital Affiliated to China Medical University, Shenyang, China., Gong H; Department of Rheumatology and Clinical Immunology, Peace Hospital Affiliated to Changzhi Medical College, Changzhi, China., Zhu J; Department of Rheumatology and Immunology, Sichuan Provincial People's Hospital, Chengdu, China., Li Y; Department of Rheumatology and Clinical Immunology, Zhejiang Provincial People's Hospital, Hangzhou, China., Wei H; Rheumatology and Immunology Department, Northern Jiangsu People's Hospital, Yangzhou, China., Qian L; Department of Rheumatology and Clinical Immunology, The Second Hospital of Anhui Medical University, Anhui, China., Wang J; Department of Rheumatology and Clinical Immunology, The First Affiliated Hospital of Bengbu Medical College, Anhui, China., Shi X; Department of Rheumatology and Clinical Immunology, The First Affiliated Hospital of Henan University of Science & Technology, Luoyang, China., Jin H; Department of Rheumatology and Immunology, The Second Hospital of Hebei Medical University, Shijiazhuang, China., Jiang Z; Department of Rheumatic Immunity, The First Hospital of Jilin University, Changchun, China., Xie X; Department of Clinical Immunology, The Second Xiangya Hospital of Central South University, Changsha, China., Zhan F; Department of Rheumatology and Immunology, Hainan General Hospital, Haikou, China., Geng X; Department of Rheumatology and Immunology, Xinxiang Central Hospital, Xinxiang, China., Zheng Z; Department of Clinical Immunology, Xijing Hospital, the Fourth Military Medical University, Xi'an, China., Du Z; Department of Rheumatology and Immunology, Yuncheng Central Hospital, Yuncheng, China., Dong G; Clinical Research & Development, Jiangsu Hengrui Pharmaceuticals, Shanghai, China., Sun Y; Biometric Department, Jiangsu Hengrui Pharmaceuticals, Shanghai, China., Zeng X; Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Beijing, China zengxfpumc@163.com xiaofeng.zeng@cstar.org.cn.

Publikováno v: Annals of the rheumatic diseases [Ann Rheum Dis] 2024 Nov 27. Date of Electronic Publication: 2024 Nov 27.