Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Donato Santovito"'
Autor:
Svenja Adam, Sanne L. Maas, Rosanna Huchzermeier, Leonida Rakateli, Kathrin Abschlag, Mathias Hohl, Liangliang Liao, Matthias Bartneck, Margee Teunissen, Kristiaan Wouters, Donato Santovito, Joachim Jankowski, Erik A.L. Biessen, Emiel P.C. van der Vorst
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105293- (2024)
Summary: Background: Female mice are more resistant to obesogenic effects of a high-fat diet (HFD), compared to male mice. Although the underlying mechanisms are poorly understood, sex hormones seem to play an important role. Interestingly, the activ
Externí odkaz:
https://doaj.org/article/5c34e5143fad4d869b8e96f2511c8b5a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Autophagy is an evolutionarily conserved mechanism of cell adaptation to metabolic and environmental stress. It mediates the disposal of protein aggregates and dysfunctional organelles, although non-conventional features have recently emerged to broa
Externí odkaz:
https://doaj.org/article/3ebdfda9aa6548f4875619417a500e53
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/a2687f58c60848b49a94d88e16e34ad7
Autor:
Donato Santovito, Lisa Toto, Velia De Nardis, Pamela Marcantonio, Rossella D’Aloisio, Alessandra Mastropasqua, Domenico De Cesare, Marco Bucci, Camilla Paganelli, Lucia Natarelli, Christian Weber, Agostino Consoli, Rodolfo Mastropasqua, Francesco Cipollone
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Diabetic retinopathy (DR) is a leading cause of vision loss and disability. Effective management of DR depends on prompt treatment and would benefit from biomarkers for screening and pre-symptomatic detection of retinopathy in diabetic patie
Externí odkaz:
https://doaj.org/article/35cd4b47215748fbab275edf21118cab
Autor:
Isabell Bernlochner, Melissa Klug, Ditya Larasati, Moritz Von Scheidt, Donato Santovito, Michael Hristov, Christian Weber, Karl-Ludwig Laugwitz, Dario Bongiovanni
Publikováno v:
Platelets, Vol 32, Iss 1, Pp 113-119 (2021)
Reticulated Platelets (RPs) are large, RNA-rich, prothrombotic and hyperactive platelets known to be elevated in high-risk populations such as diabetics and patients with acute coronary syndrome. High levels of RPs correlate with mortality and advers
Externí odkaz:
https://doaj.org/article/c8825c22545d411185406daf60f62f42
Autor:
Donato Santovito, Christian Weber
Publikováno v:
EBioMedicine, Vol 67, Iss , Pp 103366- (2021)
Externí odkaz:
https://doaj.org/article/df05fc86b0a74075bb190af77b261e9c
Autor:
Linsey J. F. Peters, Constance C. F. M. J. Baaten, Sanne L. Maas, Chang Lu, Magdolna Nagy, Natalie J. Jooss, Kiril Bidzhekov, Donato Santovito, Daniel Moreno-Andrés, Joachim Jankowski, Erik A. L. Biessen, Yvonne Döring, Johan W. M. Heemskerk, Christian Weber, Marijke J. E. Kuijpers, Emiel P. C. van der Vorst
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 983 (2022)
Platelets are key regulators of haemostasis, making platelet dysfunction a major driver of thrombosis. Numerous processes that determine platelet function are influenced by microRNAs (miRs). MiR-26b is one of the highest-expressed miRs in healthy pla
Externí odkaz:
https://doaj.org/article/f0a6572391d844a89382e9f7e97577a0
Autor:
Linsey J. F. Peters, Erik A. L. Biessen, Mathias Hohl, Christian Weber, Emiel P. C. van der Vorst, Donato Santovito
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
MicroRNAs (miRNAs) are short sequences of non-coding RNA that play an important role in the regulation of gene expression and thereby in many physiological and pathological processes. Furthermore, miRNAs are released in the extracellular space, for e
Externí odkaz:
https://doaj.org/article/4e51a0338aa641f580a9a917197320b9
Publikováno v:
Cells, Vol 10, Iss 3, p 625 (2021)
Atherosclerosis is a chronic inflammatory disease of the arterial vessel wall and underlies the development of cardiovascular diseases, such as myocardial infarction and ischemic stroke. As such, atherosclerosis stands as the leading cause of death a
Externí odkaz:
https://doaj.org/article/a31bea0a76ef4dd7b2e18b59204d2b92
Autor:
Zhihua Wang, Xi Zhang, Shu Lu, Chuankai Zhang, Zhe Ma, Rui Su, Yuanfang Li, Ting Sun, Yutao Li, Mingyang Hong, Xinyi Deng, Mohammad Rafiee Monjezi, Michael Hristov, Sabine Steffens, Donato Santovito, Klaus Dornmair, Klaus Ley, Christian Weber, Sarajo K. Mohanta, Andreas J. R. Habenicht, Changjun Yin
Publikováno v:
Nature Cardiovascular Research. 2:290-306
Atherosclerotic plaques form in the inner layer of arteries triggering heart attacks and strokes. Although T cells have been detected in atherosclerosis, tolerance dysfunction as a disease driver remains unexplored. Here we examine tolerance checkpoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e118fe6e94bdfea636e11d488e190ba9
https://doi.org/10.1038/s44161-023-00218-w
https://doi.org/10.1038/s44161-023-00218-w