Výsledky vyhledávání - "Donato Barbato"

Akademický článek

Preclinical Validation of Tc–Annexin A5–128 in Experimental Autoimmune Myocarditis and Infective Endocarditis: Comparison with Tc–HYNIC–Annexin A5

Autor: Khadija Benali, Liliane Louedec, Rana Ben Azzouna, Olivier Merceron, Pierre Nassar, Faisal Al Shoukr, Anne Petiet, Donato Barbato, Jean-Baptiste Michel, Laure Sarda-Mantel, Dominique Le Guludec, Francois Rouzet

Publikováno v: Molecular Imaging, Vol 14 (2015)

Hydrazinonicotinamide–annexin A5 (HYNIC-Anx), a 99m technetium ( 99m Tc)-labeled agent targeting phosphatidylserine, proved to be sensitive for the detection of apoptosis and thrombosis but is no longer available for clinical use. A mutant of human

Externí odkaz: https://doaj.org/article/0fd1db2324bc45ed870166983e9481ec

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Akademický článek

NeoBOMB1, a GRPR-Antagonist for Breast Cancer Theragnostics: First Results of a Preclinical Study with [67Ga]NeoBOMB1 in T-47D Cells and Tumor-Bearing Mice

Autor: Aikaterini Kaloudi, Emmanouil Lymperis, Athina Giarika, Simone Dalm, Francesca Orlandi, Donato Barbato, Mattia Tedesco, Theodosia Maina, Marion de Jong, Berthold A. Nock

Publikováno v: Molecules, Vol 22, Iss 11, p 1950 (2017)

Background: The GRPR-antagonist-based radioligands [67/68Ga/111In/177Lu]NeoBOMB1 have shown excellent theragnostic profiles in preclinical prostate cancer models, while [68Ga]NeoBOMB1 effectively visualized prostate cancer lesions in patients. We wer

Externí odkaz: https://doaj.org/article/2fd91a26029645ea860c5bc702710e95

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In Vivo Biodistribution and Efficacy Evaluation of NeoB, A Radiotracer Targeted to GRPR, in Mice Bearing Gastrointestinal Stromal Tumor

Autor: Christopher, Montemagno, Florian, Raes, Mitra, Ahmadi, Sandrine, Bacot, Marlène, Debiossat, Julien, Leenhardt, Jean, Boutonnat, Francesca, Orlandi, Donato, Barbato, Mattia, Tedesco, Catherine, Ghezzi, Pascale, Perret, Alexis, Broisat

Publikováno v: Cancers
Cancers, Vol 13, Iss 1051, p 1051 (2021)
Volume 13
Issue 5

NeoB is a radiotracer targeting the gastrin-releasing peptide receptor (GRPR), a G-protein–coupled receptor expressed in various cancers. The aim of the present study was to evaluate the biodistribution and efficacy of this new therapeutic agent in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::06b90edaf8381b18955f80c13e2d04d6
http://europepmc.org/articles/PMC7958597

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COVID-19 Patient Management in Outpatient Setting: A Population-Based Study from Southern Italy

Autor: Salvatore Crisafulli, Valentina Ientile, Luca L’Abbate, Andrea Fontana, Claudio Linguiti, Sonia Manna, Mariangela Mercaldo, Claudia Pagliaro, Michele Vezzaro, Katia Santacà, Riccardo Lora, Ugo Moretti, Chiara Reno, Maria Pia Fantini, Salvatore Corrao, Donato Barbato, Michele Tari, Gianluca Trifirò, the ITA-COVID: COV-OUT Group

Publikováno v: Journal of Clinical Medicine; Volume 11; Issue 1; Pages: 51
Journal of Clinical Medicine, Vol 11, Iss 51, p 51 (2022)
Journal of Clinical Medicine

Evidence on treatments for early-stage COVID-19 in outpatient setting is sparse. We explored the pattern of use of drugs prescribed for COVID-19 outpatients’ management in Southern Italy in the period February 2020–January 2021. This population-b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab05f7ec0a923d06e282d3c591e8cec
https://doi.org/10.3390/jcm11010051

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Ga-68/Lu-177-NeoBOMB1, a Novel Radiolabeled GRPR Antagonist for Theranostic Use in Oncology

Autor: Erik de Blois, Donato Barbato, Mark Konijnenberg, Mattia Tedesco, Berthold A. Nock, Gabriela N. Doeswijk, Francesca Orlandi, Theodosia Maina, Marion de Jong, Simone U. Dalm, Ingrid L. Bakker

Publikováno v: Journal of Nuclear Medicine, 58(2), 293-299. Society of Nuclear Medicine and Molecular Imaging

Because overexpression of the gastrin-releasing peptide receptor (GRPR) has been reported on various cancer types, for example, prostate cancer and breast cancer, targeting this receptor with radioligands might have a significant impact on staging an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b8e227e79ff1e62215ace276fccd9c
https://pure.eur.nl/en/publications/ba104ddc-789c-407b-b6f2-99705703c725

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NeoBOMB1, a GRPR-Antagonist for Breast Cancer Theragnostics: First Results of a Preclinical Study with [67Ga]NeoBOMB1 in T-47D Cells and Tumor-Bearing Mice

Autor: Donato Barbato, Berthold A. Nock, Theodosia Maina, Athina Giarika, Simone U. Dalm, Marion de Jong, Emmanouil Lymperis, Aikaterini Kaloudi, Francesca Orlandi, Mattia Tedesco

Publikováno v: Molecules; Volume 22; Issue 11; Pages: 1950
Molecules, 22(11):1950. Multidisciplinary Digital Publishing Institute (MDPI)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 22, Iss 11, p 1950 (2017)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb11933b69246c2b7fc81a471c5bce2

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Preclinical validation of 99mTc-annexin A5-128 in experimental autoimmune myocarditis and infective endocarditis: comparison with 99mTc-HYNIC-annexin A5

Autor: Khadija Benali, Laure Sarda-Mantel, Anne Petiet, Dominique Le Guludec, Olivier Merceron, Liliane Louedec, François Rouzet, Pierre Nassar, Jean-Baptiste Michel, Faisal Al Shoukr, Donato Barbato, Rana Ben Azzouna

Publikováno v: Molecular imaging. 13

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e6c981c3e90a7848746a3d1ced2b4f
https://pubmed.ncbi.nlm.nih.gov/25431156

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