Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Donatella Valenti"'
Autor:
Ines Castangia, Matteo Aroffu, Mohamad Allaw, Matteo Perra, Biancamaria Baroli, Iris Usach, José Esteban Peris, Donatella Valenti, Octavio Diez-Sales, Amparo Ruiz Sauri, Amparo Nacher, Xavier Fernàndez-Busquets, Maria Manconi, Maria Letizia Manca
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116998- (2024)
Inflammatory skin disorders are the fourth leading cause of chronic non-fatal conditions, which have a serious impact on the patient quality of life. Due to their treatment with conventional corticosteroids, which often result in poor therapeutic eff
Externí odkaz:
https://doaj.org/article/e62e448d8d9d4f83b0ea69e6a4502a2d
Autor:
Luca Casula, Rosa Pireddu, Maria Cristina Cardia, Elena Pini, Donatella Valenti, Michele Schlich, Chiara Sinico, Salvatore Marceddu, Nina Dragićević, Anna Maria Fadda, Francesco Lai
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2308 (2023)
Applying a formulation on the skin represents a patient-acceptable and therapeutically effective way to administer drugs locally and systemically. However, the stratum corneum stands as an impermeable barrier that only allows a very limited number of
Externí odkaz:
https://doaj.org/article/2b2326eefe3d41fa8c845a2b030e602d
Autor:
Michele Schlich, Luca Casula, Aurora Musa, Rosa Pireddu, Giulia Pitzanti, Maria Cristina Cardia, Donatella Valenti, Salvatore Marceddu, Anna Maria Fadda, Maria Antonietta De Luca, Chiara Sinico, Francesco Lai
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1085 (2022)
Needle-free liquid jet injectors are medical devices used to administer pharmaceutical solutions through the skin. Jet injectors generate a high-speed stream of liquid medication that can puncture the skin and deliver the drug to the underlying tissu
Externí odkaz:
https://doaj.org/article/4318cd979142402593fb507e131a1410
Autor:
Luca Casula, Francesco Lai, Elena Pini, Donatella Valenti, Chiara Sinico, Maria Cristina Cardia, Salvatore Marceddu, Giorgia Ailuno, Anna Maria Fadda
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1300 (2021)
Curcumin has shown a potential extraordinary activity as an add-on ingredient in asthma treatment, due to its immunomodulatory and anti-inflammatory mechanism of action. However, its low water solubility and bioavailability lead to a poor therapeutic
Externí odkaz:
https://doaj.org/article/5bd777547c0c49cf87fff4f6fcfb38e2
Autor:
Lucia Montenegro, Ludovica Maria Santagati, Maria Grazia Sarpietro, Francesco Castelli, Annamaria Panico, Edy Angela Siciliano, Francesco Lai, Donatella Valenti, Chiara Sinico
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 1027 (2021)
Lipid nanoparticles (LNPs) have been proposed as carriers for drug skin delivery and targeting. As LNPs effectiveness could be increased by the addition of chemical penetration enhancers (PE), in this work, the feasibility of incorporating PE into LN
Externí odkaz:
https://doaj.org/article/48c9ae988df44e79814e8f99a05bf620
Autor:
Maria Letizia Manca, Maria Ferraro, Elisabetta Pace, Serena Di Vincenzo, Donatella Valenti, Xavier Fernàndez-Busquets, Catalina Anisoara Peptu, Maria Manconi
Publikováno v:
Nanomaterials, Vol 11, Iss 4, p 850 (2021)
In this work beclomethasone dipropionate was loaded into liposomes and hyalurosomes modified with mucin to improve the ability of the payload to counteract the oxidative stress and involved damages caused by cigarette smoke in the airway. The vesicle
Externí odkaz:
https://doaj.org/article/04258860ba5d45a18dd662ff5dd6e162
Autor:
Rosa Pireddu, Michele Schlich, Salvatore Marceddu, Donatella Valenti, Elena Pini, Anna Maria Fadda, Francesco Lai, Chiara Sinico
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1140 (2020)
Topical application of the anti-inflammatory drug diclofenac (DCF) reduces the severity of systemic unwanted effects compared to its oral administration. A number of transdermal formulations are available on the market and routinely used in clinical
Externí odkaz:
https://doaj.org/article/71d35a53a4cb43dea63233bd7c974ab3
Autor:
Giulia Pitzanti, Antonella Rosa, Mariella Nieddu, Donatella Valenti, Rosa Pireddu, Francesco Lai, Maria Cristina Cardia, Anna Maria Fadda, Chiara Sinico
Publikováno v:
Pharmaceutics, Vol 12, Iss 10, p 973 (2020)
Topical psoralens plus ultraviolet A radiation (PUVA) therapy consists in the topical application of 8-methoxypsoralen (8-MOP) followed by the skin irradiation with ultraviolet A radiation. The employment of classical 8-MOP vehicles in topical PUVA t
Externí odkaz:
https://doaj.org/article/92af2c44cdc94197a057e4b0832a4f7a
Autor:
Maria Letizia Manca, Iris Usach, José Esteban Peris, Antonella Ibba, Germano Orrù, Donatella Valenti, Elvira Escribano-Ferrer, Juan Carmelo Gomez-Fernandez, Francisco José Aranda, Anna Maria Fadda, Maria Manconi
Publikováno v:
Pharmaceutics, Vol 11, Iss 6, p 263 (2019)
New three-dimensionally-structured hybrid phospholipid vesicles, able to load clotrimazole in a high amount (10 mg/mL), were obtained for the first time in this work by significantly reducing the amount of water (≤10%), which was replaced with a mi
Externí odkaz:
https://doaj.org/article/6ce65282c34e40799531caf99c5a7159
Autor:
Maria Manconi, Anna Maria Fadda, Chiara Sinico, Donatella Valenti, Carla Caddeo, Maura Chessa
Publikováno v:
Pharmaceutics, Vol 3, Iss 3, Pp 497-509 (2011)
Quercetin (3,3′,4′,5,7-pentahydroxyflavone) exerts multiple pharmacological effects: anti-oxidant activity, induction of apoptosis, modulation of cell cycle, anti-mutagenesis, and anti-inflammatory effect. In topical formulations quercetin inhibi
Externí odkaz:
https://doaj.org/article/5046502c325b4466803443d44b32b59a