Výsledky vyhledávání - "Donatella Pietrangelo"

Akademický článek

Early and late gut microbiota signatures of stroke in high salt-fed stroke-prone spontaneously hypertensive rats

Autor: Silvia Bencivenni, Sara Roggiani, Augusta Zannoni, Gabriele Conti, Marco Fabbrini, Maria Cotugno, Rosita Stanzione, Donatella Pietrangelo, Margherita Litterio, Maurizio Forte, Carla Letizia Busceti, Francesco Fornai, Massimo Volpe, Silvia Turroni, Patrizia Brigidi, Monica Forni, Speranza Rubattu, Federica D’Amico

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Abstract The high salt-fed stroke-prone spontaneously hypertensive rat (SHRSP) is a suitable tool to study the mechanisms underlying stroke pathogenesis. Salt intake modifies the gut microbiota (GM) in rats and humans and alterations of the GM have p

Externí odkaz: https://doaj.org/article/90c4a6fbb86c477f9c96d026967c9231

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Akademický článek

Molecular mechanisms of naringenin modulation of mitochondrial permeability transition acting on F1FO-ATPase and counteracting saline load-induced injury in SHRSP cerebral endothelial cells

Autor: Salvatore Nesci, Cristina Algieri, Matteo Antonio Tallarida, Rosita Stanzione, Saverio Marchi, Donatella Pietrangelo, Fabiana Trombetti, Luca D’Ambrosio, Maurizio Forte, Maria Cotugno, Ilaria Nunzi, Rachele Bigi, Loredana Maiuolo, Antonio De Nino, Paolo Pinton, Giovanni Romeo, Speranza Rubattu

Publikováno v: European Journal of Cell Biology, Vol 103, Iss 2, Pp 151398- (2024)

Naringenin (NRG) was characterized for its ability to counteract mitochondrial dysfunction which is linked to cardiovascular diseases. The F1FO-ATPase can act as a molecular target of NRG. The interaction of NRG with this enzyme can avoid the energy

Externí odkaz: https://doaj.org/article/fa6f92a0d76e4bf882977013dbb4485a

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Akademický článek

Role of autophagy in ischemic stroke: insights from animal models and preliminary evidence in the human disease

Autor: Rosita Stanzione, Donatella Pietrangelo, Maria Cotugno, Maurizio Forte, Speranza Rubattu

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 12 (2024)

Stroke represents a main cause of death and permanent disability worldwide. The molecular mechanisms underlying cerebral injury in response to the ischemic insults are not completely understood. In this article, we summarize recent evidence regarding

Externí odkaz: https://doaj.org/article/401aad731ccf494cbcd9ad0eeed374b3

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