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Retinoid-related orphan receptor γ (RORγ) adult induced knockout mice develop lymphoblastic lymphoma
Autor:
Camilla Johansson, Magnus Söderberg, Jenny Börjesson, Jorrit J. Hornberg, Marie Ramnegård, Maria Rehnberg, Maria Liljevald, Donatella Luciani, Johan Jirholt, Ulf Andersson, Lena Brändén, David J. Keeling, Anna-Karin Sjögren, Xiufeng Xu, Nina Krutrök, Mikael Bjursell
Publikováno v:
Autoimmunity Reviews. 15:1062-1070
RORγ is a nuclear hormone receptor which controls polarization of naive CD4+ T-cells into proinflammatory Th17 cells. Pharmacological antagonism of RORγ has therapeutic potential for autoimmune diseases; however, this mechanism may potentially carr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32327bd242dabcc76c9a6e58cd89b0d
https://doi.org/10.1016/j.autrev.2016.07.036
https://doi.org/10.1016/j.autrev.2016.07.036
