Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Donatella Carpi"'
Autor:
Francesca Pistollato, Emilio Mendoza de Gyves, Donatella Carpi, Stephanie K. Bopp, Carolina Nunes, Andrew Worth, Anna Bal-Price
Publikováno v:
Environmental Health, Vol 19, Iss 1, Pp 1-26 (2020)
Abstract Background In light of the vulnerability of the developing brain, mixture risk assessment (MRA) for the evaluation of developmental neurotoxicity (DNT) should be implemented, since infants and children are co-exposed to more than one chemica
Externí odkaz:
https://doaj.org/article/e6f721fffcac4e86bba91ff628913776
Autor:
Julia M. Malinowska, Taina Palosaari, Jukka Sund, Donatella Carpi, Gavin R. Lloyd, Ralf J. M. Weber, Maurice Whelan, Mark R. Viant
Publikováno v:
Metabolites, Vol 12, Iss 1, p 52 (2022)
Regulatory bodies have started to recognise the value of in vitro screening and metabolomics as two types of new approach methodologies (NAMs) for chemical risk assessments, yet few high-throughput in vitro toxicometabolomics studies have been report
Externí odkaz:
https://doaj.org/article/94462e96c0024fd68ed3af5b611bcd89
Autor:
Carolina Nunes, Gabriela Gorczyca, Emilio Mendoza-deGyves, Jessica Ponti, Alessia Bogni, Donatella Carpi, Anna Bal-Price, Francesca Pistollato
Publikováno v:
Reproductive Toxicology. 110:124-140
Human induced pluripotent stem cell (iPSC)-derived neuronal and glial cell models are suitable to assess the effects of environmental chemicals on the developing brain. Such test systems can recapitulate several key neurodevelopmental features, such
Publikováno v:
Journal of Alzheimer's Disease. 86:1427-1457
Background: A complex network of aging-related homeostatic pathways that are sensitive to further deterioration in the presence of genetic, systemic, and environmental risk factors, and lifestyle, is implicated in the pathogenesis of progressive neur
Autor:
Francesca Pistollato, Ragnhild E. Paulsen, Anna Bal-Price, Erik Ropstad, Hubert Dirven, Donatella Carpi, Hanne Friis Berntsen, Nichlas Davidsen, Anna Jacobsen Lauvås, Emilio Mendoza-de Gyves, Oddvar Myhre
Publikováno v:
Reproductive Toxicology (Elmsford, N.y.)
Reproductive Toxicology
Reproductive Toxicology
Highlights • Mixtures of 29 halogenated POPs were reconstructed based on human blood levels. • In vitro assays permitted to evaluate DNT effects in human iPSC-derived NSCs. • POPs at human blood levels increased proliferating NSCs and decreased
Autor:
Alicia Paini, Emilio Mendoza-de Gyves, Stephanie K. Bopp, Anna Bal-Price, Andrew Worth, Donatella Carpi, Francesca Pistollato
Publikováno v:
Reproductive Toxicology (Elmsford, N.y.)
Highlights • Mixtures of similar MoA chemicals increased BDNF levels and neurite outgrowth. • Mixtures of similar MoA chemicals decreased synapse formation and electrical activity. • Synergistic effects on synaptogenesis features was predicted
Autor:
Emilio Mendoza-de Gyves, Andrew Worth, Donatella Carpi, Anna Bal-Price, Stephanie K. Bopp, Carolina Nunes, Francesca Pistollato
Publikováno v:
Environmental Health, Vol 19, Iss 1, Pp 1-26 (2020)
Environmental Health
Environmental Health
Background In light of the vulnerability of the developing brain, mixture risk assessment (MRA) for the evaluation of developmental neurotoxicity (DNT) should be implemented, since infants and children are co-exposed to more than one chemical at a ti
Autor:
Pietro Invernizzi, Alessio Gerussi, Luigi Muratori, Anna Torri, Sergio Abrignani, Antonia Sinisi, Jens Geginat, Mariacristina Crosti, Francesca Bernuzzi, Donatella Carpi, Monica Moro, Chiara Cordiglieri, Elisa Pesce, Renata Grifantini, Mauro Bombaci, Manuela Lanzafame, Luigi Terracciano
Publikováno v:
Liver international : official journal of the International Association for the Study of the LiverREFERENCES. 39(11)
Background and aims: Primary biliary cholangitis is an autoimmune biliary disease characterized by injury of bile ducts, eventually leading to cirrhosis and death. In most cases, anti-mitochondrial antibodies and persistently elevated serum alkaline
Autor:
Giulia Casorati, Paola de Candia, Valentina Viganò, Paolo Dellabona, Massimiliano Pagani, Maya Fedeli, Anna Torri, Sergio Abrignani, Donatella Carpi, Tatiana Gorletta
Publikováno v:
Europe PubMed Central
Upon activation, lymphocytes release vesicles containing microRNAs (miRNAs). However, little is known as to whether this release results in modulation of circulating miRNAs (the miRNome) in the serum. The present work aims to identify lymphocyte subs
Autor:
Donatella Carpi, Riccardo L. Rossi, Sergio Abrignani, Massimiliano Pagani, Raoul J. P. Bonnal, Valeria Ranzani
Publikováno v:
Nucleic Acids Research
The miRBase is the official miRNA repository which keeps the annotation updated on newly discovered miRNAs: it is also used as a reference for the design of miRNA profiling platforms. Nomenclature ambiguities generated by loosely updated platforms an